PhD ceremony: Ms. B.T.F. van der Gun, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Regulation and epigenetic modulation of EpCAM gene expression in ovarian cancer
Promotor(s): prof. M.G. Rots, prof. L.F.M.H. de Leij
Faculty: Medical Sciences
The Epithelial Cell Adhesion Molecule (EpCAM) is a protein that is abundantly present on the surface of tumor cells of almost all carcinoma types. Inhibition of the production of this protein decreases aggressiveness of the tumor cells in some carcinoma types, for example in breast cancer. However, until now, protein production can only be reduced transiently. In this research the regulation of the gene which encodes for the EpCAM protein is studied and three methods has been developed to silence EpCAM gene expression in a permanent manner.
4 to 5.30 p.m.
The 51st edition of KEI week is devoted to the theme of sustainability. On Monday 12 August, around 6,000 KEI participants and KEI leaders were handed cloth bags instead of plastic ones and a KEI wristband with a chip enabling digital payments. A vegetarian...
Recent studies into the relationship between decreases in sea ice in the Arctic and ice-cold winters in the mid-latitudes, like the Polar Vortex cold waves in North America, seem to suggest that such a connection does indeed exist. However, the mechanisms...