PhD ceremony: Ms. T.M. Geel, 14.45 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Pompe disease: towards gene correction using targeted nucleases
Promotor(s): prof. M.G. Rots
Faculty: Medical Sciences
Pompe disease is an inherited metabolic disorder caused by a mutation in the gene encoding the enzyme acid-α-glucosidase (GAA). In this dissertation, novel strategies were investigated to improve the treatment of Pompe disease. The only currently available therapy (Enzyme Replacement Therapy) is hampered by several disadvantages such as inefficient uptake of the enzyme. We demonstrated that a known efficient DNA carrier (SAINT) could also be used to effectively deliver proteins, including lysosomal enzymes and restriction enzymes.
Virtueel zwemmen met dolfijnen of een wandelen door het bos: uit onderzoek van het UMCG blijkt dat IC-verpleegkundigen hierdoor 40% minder stress ervaren.
Different from previous years but still surprising, fun, healthy, and for the whole family: join Groningen’s take on this year’s national weekend of science, organized by the University of Groningen (UG) and Hanze University of Applied Sciences...
Northern Netherlands Top Dutch Solar Racing team joins forces to prepare for solar race in Morocco.
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