PhD ceremony: ms. N. Hsiao, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Characterization of key proteins involved in the SCB signalling system for secondary metabolism in Streptomyces coelicolor
Promotor(s): prof. L. Dijkhuizen
Faculty: Mathematics and Natural Sciences
Nai-Hua Hsiao investigated the enzymatic role of ScbA in the biosynthetic pathway of
-butyrolactones in Streptomyce coelicolor which is strongly suggested by active site mutagenesis. In addition to the enzymatic function, ScbA may also possess a role in the regulation of antibiotic production and morphological differentiation. It seems that ScbA has dual function in S. coelicolor concludes Hsiao.
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