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How to find us prof. dr. W. (Wijnand) Helfrich
University Medical Center Groningen

prof. dr. W. (Wijnand) Helfrich

Publications

Publications

Synthesis and evaluation of 18F-enzalutamide, a new radioligand for PET Imaging of Androgen Receptors: A comparison with 16β-18F-fluoro-5α-dihydrotestosterone

Farinha Antunes, I. , Dost, R., Hoving, H. D. , van Waarde, A. , Dierckx, R. A. , Samplonius, D. F. , Helfrich, W. , Elsinga, P. H. , de Vries, E. F. & de Jong, I. J. , 1-Feb-2021 , In: Journal of Nuclear Medicine. 62 , 2

Research output: Contribution to journal › Article › Academic › peer-review

Bispecific antibody approach for EGFR-directed blockade of the CD47-SIRP alpha "don't eat me" immune checkpoint promotes neutrophil-mediated trogoptosis and enhances antigen cross-presentation

Hendriks, M. A. J. M., Ploeg, E. M. , Koopmans, I. , Britsch, I. , Ke, X. , Samplonius, D. F. & Helfrich, W. , 2020 , In: OncoImmunology. 9 , 1 , p. 1-12 12 p. , 1824323.

Research output: Contribution to journal › Article › Academic › peer-review

Modular Medical Imaging Agents Based on Azide-Alkyne Huisgen Cycloadditions: Synthesis and Pre-Clinical Evaluation of(18)F-Labeled PSMA-Tracers for Prostate Cancer Imaging

Böhmer, V. I., Szymanski, W. , van den Berg, K-O., Mulder, C., Kobauri, P. , Helbert, H. , van den Born, D., Reeβing, F., Huizing, A., Klopstra, M., Samplonius, D. F. , Antunes, I. F. , Sijbesma, J. W. A., Luurtsema, G. , Helfrich, W. , Visser, T. J., Feringa, B. L. & Elsinga, P. H. , 21-Jul-2020 , In: Chemistry. 26 , 47 , p. 10871-10881 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

A light-responsive liposomal agent for MRI contrast enhancement and monitoring of cargo delivery

Reeßing, F., Stuart, M. C. A. , Samplonius, D. F. , Dierckx, R. A. J. O. , Feringa, B. L. , Helfrich, W. & Szymanski, W. , 16-Sep-2019 , In: Chemical communications (Cambridge, England). 55 , 72 , p. 10784-10787 4 p.

Research output: Contribution to journal › Article › Academic › peer-review

Bispecific Antibody Approach for Improved Melanoma-Selective PD-L1 Immune Checkpoint Blockade

Koopmans, I. , Hendriks, M. A. J. M., van Ginkel, R. J. , Samplonius, D. F. , Bremer, E. & Helfrich, W. , Nov-2019 , In: Journal of Investigative Dermatology. 139 , 11 , p. 2343-+ 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Development of Bispecific Antibody Derivatives for Cancer Immunotherapy

He, Y., Helfrich, W. & Bremer, E. , 2019 , Cancer Immunosurveillance: Methods and Protocols. Humana Press , p. 335-347 13 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Quantitative proteomics analysis identifies MUC1 as an effect sensor of EGFR inhibition

de Boer, H. R. , Pool, M., Joosten, E., Everts, M. , Samplonius, D. F. , Helfrich, W. , Groen, H. J. M. , van Cooten, S., Fusetti, F., Fehrmann, R. S. N. , de Vries, E. G. E. & van Vugt, M. A. T. M. , 28-Feb-2019 , In: ONCOGENE. 38 , 9 , p. 1477-1488 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

A novel bispecific antibody for EGFR-directed blockade of the PD-1/PD-L1 immune checkpoint

Koopmans, I. , Hendriks, D., Samplonius, D. F. , van Ginkel, R. J. , Heskamp, S., Wierstra, P. J., Bremer, E. & Helfrich, W. , 2018 , In: OncoImmunology. 7 , 8 , 11 p. , 1466016.

Research output: Contribution to journal › Article › Academic › peer-review

Antigen-specific active immunotherapy for ovarian cancer

Paijens, S. T. , Leffers, N., Daemen, T. , Helfrich, W. , Boezen, H. M. , Cohlen, B. J., Melief, C. J., de Bruyn, M. & Nijman, H. W. , 10-Sep-2018 , (E-pub ahead of print) In: Cochrane database of systematic reviews (Online). 9 , 151 p. , CD007287.

Research output: Contribution to journal › Review article › peer-review

CD20-selective inhibition of CD47-SIRP alpha "don't eat me" signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab

van Bommel, P. E., He, Y., Schepel, I., Hendriks, M. A. J. M., Wiersma, V. R. , van Ginkel, R. J. , van Meerten, T. , Ammatuna, E. , Huls, G. , Samplonius, D. F. , Helfrich, W. & Bremer, E. , 2018 , In: OncoImmunology. 7 , 2 , 8 p. , e1386361.

Research output: Contribution to journal › Article › Academic › peer-review

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