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ing. R. van Merkerk

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Faculteit Science and Engineering

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Publicaties

Access to nitrogen-nitrogen bond-containing heterocycles through substrate promiscuity of piperazate synthases

Li, Y., Osipyan, A., de Kok, N. A. W., Schröder, S., Founti, M., Fodran, P., van Merkerk, R., Maier, A., Tischler, D. & Schmidt, S., 17-feb.-2025, (Submitted) ChemRxiv.

Onderzoeksoutput: Voordruk ›

Access to Nitrogen − nitrogen Bond-Containing Heterocycles Through Substrate Promiscuity of Piperazate Synthases

Li, Y., Osipyan, A., Kok, N. A. W. D., Schröder, S., Founti, M., Fodran, P., Merkerk, R. V., Maier, A., Tischler, D. & Schmidt, S., 6-jun.-2025, In: ACS Catalysis. 15, 11, blz. 8846-8854 9 blz.

Onderzoeksoutput › › peer review

Correction to “Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells”Article link copied!

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 27-mrt.-2025, In: Journal of Medicinal Chemistry. 68, 6, blz. 6844-6845 2 blz.

Onderzoeksoutput

High-throughput excipient screening using 384-well plates and a pipetting robot: assessing protein stability after freeze-drying to pre-select viable formulations

Zillen, D., van der Ploeg, N. N., van Merkerk, R., Poelarends, G. J., Frijlink, H. W. & Hinrichs, W. L. J., 10-nov.-2025, (E-pub ahead of print) In: Drug Development and Industrial Pharmacy. 7 blz.

Onderzoeksoutput › › peer review

Improved taxadiene production by optimizing DXS expression and fusing short-chain prenyltransferases

He, S., Bekhof, A. S. M. W., Popova, E. Z., van Merkerk, R. & Quax, W. J., 25-nov.-2024, In: New Biotechnology. 83, blz. 66-73 8 blz.

Onderzoeksoutput › › peer review

Insights into taxadiene synthase catalysis and promiscuity facilitated by mutability landscape and molecular dynamics

He, S., Abdallah, I. I., van Merkerk, R. & Quax, W. J., 9-mrt.-2024, In: Planta. 259, 4, 14 blz., 87.

Onderzoeksoutput › › peer review

The Promiscuity of Squalene Synthase-Like Enzyme: Dehydrosqualene Synthase, a Natural Squalene Hyperproducer?

Guan, Z., Song, Y., de Vries, M., Permentier, H., Tepper, P., van Merkerk, R., Setroikromo, R. & Quax, W. J., 14-feb.-2024, In: Journal of Agricultural and Food Chemistry. 72, 6, blz. 3017-3024 8 blz.

Onderzoeksoutput › › peer review

Tailored photoenzymatic systems for selective reduction of aliphatic and aromatic nitro compounds fueled by light

Luján, A. P., Bhat, M. F., Tsaturyan, S., van Merkerk, R., Fu, H. & Poelarends, G. J., 6-sep.-2023, In: Nature Communications. 14, 1, 10 blz., 5442.

Onderzoeksoutput › › peer review

Development and application of CRISPR-based genetic tools in Bacillus species and Bacillus phages

Song, Y., He, S., Jopkiewicz, A., Setroikromo, R., van Merkerk, R. & Quax, W. J., okt.-2022, In: Journal of Applied Microbiology. 133, 4, blz. 2280-2298 19 blz.

Onderzoeksoutput › peer review

Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d -Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 10-feb.-2022, In: Journal of Medicinal Chemistry. 65, 3, blz. 2059-2077

Onderzoeksoutput › › peer review

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