R. Oelen

Faculty of Medical Sciences

Telephone:

+31 50 361 5685

E-mail:

r.oelen umcg.nl

ORCID Research Portal

Publications

Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases

de Klein, N., Tsai, E. A., Vochteloo, M., Baird, D., Huang, Y., Chen, C. Y., van Dam, S., Oelen, R., Deelen, P., Bakker, O. B., El Garwany, O., Ouyang, Z., Marshall, E. E., Zavodszky, M. I., van Rheenen, W., Bakker, M. K., Veldink, J., Gaunt, T. R., Runz, H., Franke, L., & 1 othersWestra, H. J., Mar-2023, In: Nature genetics. 55, 3, p. 377-388 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

BIOS Consortium, sc-eQTLgen Consortium, Li, S., Schmid, K. T., de Vries, D. H., Korshevniuk, M., Losert, C., Oelen, R., van Blokland, I. V., Groot, H. E., Swertz, M. A., van der Harst, P., Westra, H. J., van der Wijst, M. G. P., Heinig, M. & Franke, L., 18-Apr-2023, In: Genome Biology. 24, 37 p., 80.

Research output: Contribution to journal › Article › Academic › peer-review

Integration of Candida albicans-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation

Boahen, C. K., Oelen, R., Le, K., Netea, M. G., Franke, L., Wijst, M. G. P. V. D. & Kumar, V., 14-Feb-2023, In: Frontiers in Immunology. 14, 13 p., 1069379.

Research output: Contribution to journal › Article › Academic › peer-review

KidneyNetwork: Using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease

Genomics England Research Consortium, Boulogne, F., Claus, L. R., Wiersma, H., Oelen, R., Schukking, F., de Klein, N., Li, S., Westra, H. J., van der Zwaag, B., van Reekum, F., Sierks, D., Schönauer, R., Li, Z., Bijlsma, E. K., Bos, W. J. W., Halbritter, J., Knoers, N. V. A. M., Besse, W., Deelen, P., & 2 othersFranke, L. & van Eerde, A. M., Nov-2023, In: European Journal of Human Genetics. 31, p. 1300–1308 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Multi-Omic Factor Analysis uncovers immunological signatures with pathophysiologic and clinical implications in coronary syndromes

Pekayvaz, K., Losert, C., Knottenberg, V., van Blokland, I. V., Oelen, R., Groot, H. E., Benjamins, J. W., Brambs, S., Kaiser, R., Eivers, L., Polewka, V., Escaig, R., Joppich, M., Janjic, A., Popp, O., Petzold, T., Zimmer, R., Enard, W., Saar, K., Mertins, P., & 8 othersHuebner, N., van der Harst, P., Franke, L. H., van der Wijst, M. G. P., Massberg, S., Heinig, M., Nicolai, L. & Stark, K., 3-May-2023, (Submitted) MedRxiv.

Research output: Working paper › Preprint › Academic

Single-cell dissection of the immune response after acute myocardial infarction

van Blokland, I. V., Oelen, R., Groot, H. E., Benjamins, J. W., Pekayvaz, K., Losert, C., Knottenberg, V., Heinig, M., Nicolai, L., Stark, K., van der Harst, P., Franke, L. H. & van der Wijst, M. G. P., 2-May-2023, MedRxiv.

Research output: Working paper › Preprint › Academic

Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure

Single-Cell EQTLGen Consortium, Bios Consortium , Oelen, R., de Vries, D. H., Brugge, H., Gordon, M. G., Vochteloo, M., Ye, C. J., Westra, H-J., Franke, L. & van der Wijst, M. G. P., 7-Jun-2022, In: Nature Communications. 13, 1, 15 p., 3267.

Research output: Contribution to journal › Article › Academic › peer-review

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

BIOS Consortium, i2QTL Consortium, Võsa, U., Claringbould, A., Westra, H-J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Yazar, S., Brugge, H., Oelen, R., de Vries, D. H., van der Wijst, M. G. P., Kasela, S., Pervjakova, N., Alves, I., Fave, M-J., & 32 othersAgbessi, M., Christiansen, M. W., Jansen, R., Seppala, I., Tong, L., Teumer, A., Schramm, K., Hemani, G., Verlouw, J., Yaghootkar, H., Flitman, R. S., Brown, A., Kukushkina, V., Kalnapenkis, A., Rueger, S., Porcu, E., Kronberg, J., Kettunen, J., Lee, B., Zhang, F., Qi, T., Hernandez, J. A., Arindrarto, W., Beutner, F., Dmitrieva, J., Li, S., Penninx, B. W. J. H., Veldink, J. H., Warmerdam, R., Wijmenga, C., Swertz, M. & Franke, L., Sept-2021, In: Nature Genetics. 53, 9, p. 1300-1310 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Multi-infusion with integrated multiple pressure sensing allows earlier detection of line occlusions

Doesburg, F., Oelen, R., Renes, M. H., Lourenço, P. M., Touw, D. J. & Nijsten, M. W., 28-Oct-2021, In: BMC Medical Informatics and Decision Making. 21, 12 p., 295.

Research output: Contribution to journal › Article › Academic › peer-review

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

BIOS Consortium, Aguirre-Gamboa, R., de Klein, N., di Tommaso, J., Claringbould, A., van der Wijst, M. G. P., de Vries, D., Brugge, H., Oelen, R., Vosa, U., Zorro, M. M., Chu, X., Bakker, O. B., Borek, Z., Ricano-Ponce, I., Deelen, P., Xu, C-J., Swertz, M., Jonkers, I., Withoff, S., & 9 othersJoosten, I., Sanna, S., Kumar, V., Koenen, H. J. P. M., Joosten, L. A. B., Netea, M. G., Wijmenga, C., Franke, L. & Li, Y., 12-Jun-2020, In: Bmc Bioinformatics. 21, 1, 23 p., 243.

Research output: Contribution to journal › Article › Academic › peer-review

All (11) publications

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