R.I. Seinstra

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 6538

E-mail:

r.i.seinstra umcg.nl

Research Portal

Publicaties

In Vivo Nanodiamond Quantum Sensing of Free Radicals in Caenorhabditis elegans Models

Fan, S., Zhang, Y., Ainslie, A. P., Seinstra, R., Zhang, T., Nollen, E. & Schirhagl, R., 10-apr.-2025, In: Advanced science. 12, 14, 9 blz., 2412300.

Onderzoeksoutput: Article › › peer review

Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43 toxicity

Koopman, M., Güngördü, L., Janssen, L., Seinstra, R. I., Richmond, J. E., Okerlund, N., Wardenaar, R., Islam, P., Hogewerf, W., Brown, A. E. X., Jorgensen, E. M. & Nollen, E. A. A., 28-mei-2024, In: Cell reports. 43, 5, 27 blz., 114204.

Onderzoeksoutput: Article › › peer review

Neuronal overexpression of hTDP-43 in Caenorhabditis elegans impairs different neuronally controlled behaviors anddecreases fecundity.

Koopman, M., Güngördü, L., Seinstra, R. I. & Nollen, E. A. A., 19-apr.-2023, In: microPublication biology. 2023, 5 blz.

Onderzoeksoutput: Article › › peer review

Neuronal overexpression of hTDP-43 in Caenorhabditis elegans impairs motor function.

Koopman, M., Güngördü, L., Seinstra, R. I. & Nollen, E. A. A., 19-apr.-2023, In: microPublication biology. 2023, 5 blz.

Onderzoeksoutput: Article › › peer review

Neuronal overexpression of hTDP-43 in Caenorhabditis elegans mimics the cellular pathology commonly observed in TDP-43 proteinopathies.

Koopman, M., Güngördü, L., Seinstra, R. I., Hogewerf, W. & Nollen, E. A. A., 19-apr.-2023, In: microPublication biology. 2023, 7 blz.

Onderzoeksoutput: Article › › peer review

Neuronal overexpression of human TDP-43 in Caenorhabditis elegans causes a range of sensorimotor phenotypes.

Koopman, M., Güngördü, L., Seinstra, R. I. & Nollen, E. A. A., 19-apr.-2023, In: microPublication biology. 2023, 5 blz.

Onderzoeksoutput: Article › › peer review

Alpha-Synuclein Lowering and Rescue of Motor Phenotype by miRNA-Based AAV Gene Therapy in In Vivo Parkinson's Disease Models

Broekmans, S. A., Tornero, C. V., Toonen, L., Valls, M., Erbrink, R., Ronde, K. E., Hogewerf, W., Tolsma, L. E. D., Seinstra, R. I., Janssen, L. L. S., Nollen, E. A. A. & Valles, A., apr.-2022, In: Molecular Therapy. 30, 4, blz. 10-10 1 blz.

Onderzoeksoutput: Meeting Abstract ›

Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease

Perni, M., van der Goot, A., Limbocker, R., van Ham, T. J., Aprile, F. A., Xu, C. K., Flagmeier, P., Thijssen, K., Sormanni, P., Fusco, G., Chen, S. W., Challa, P. K., Kirkegaard, J. B., Laine, R. F., Ma, K. Y., Müller, M. B. D., Sinnige, T., Kumita, J. R., Cohen, S. I. A. & Seinstra, R., Kaminski Schierle, G. S., Kaminski, C. F., Barbut, D., De Simone, A., Knowles, T. P. J., Zasloff, M., Nollen, E. A. A., Vendruscolo, M. & Dobson, C. M., 22-mrt.-2021, In: Frontiers in Cell and Developmental Biology. 9, 10 blz., 552549.

Onderzoeksoutput: Article › › peer review

Dose dependent lowering of alpha-synuclein and rescue of motor phenotype by miRNA-based AAV gene therapy

Broekmans, S. A., Tornero, C. V., Akyol, F., Toonen, L., Kieper, S., Ronde, K. E., Hogewerf, W., Tolsma, E. D., Seinstra, R. I., Janssen, L. L. S., Nolen, E. A. A. & Valles, A., okt.-2021, In: Human Gene Therapy. 32, 19-20, blz. A51-A51 1 blz.

Onderzoeksoutput: Meeting Abstract ›

The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation

Pras, A., Houben, B., Aprile, F. A., Seinstra, R., Gallardo, R., Janssen, L., Hogewerf, W., Gallrein, C., De Vleeschouwer, M., Mata-Cabana, A., Koopman, M., Stroo, E., de Vries, M., Edwards, S. L., Kirstein, J., Vendruscolo, M., Falsone, S. F., Rousseau, F., Schymkowitz, J. & Nollen, E. A. A., 2-nov.-2021, In: The EMBO Journal. 40, 21, 18 blz., e107568.

Onderzoeksoutput: Article › › peer review

Alle (20) publicaties

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