dr. ir. N.M. (Marianna) Sijtsema

Medical Physicist

Faculty of Medical Sciences

Telephone:

+31 6 2110 2076

Secretary:

+31 50 361 3674

E-mail:

n.m.sijtsema umcg.nl

ORCID Research Portal

Research interests

Radiotherapy, Adaptive Radiotherapy (ART), Image Biomarkers, Radiomics, Adaptive Proton Therapy

Publications

A multi-toxicity deep learning approach for normal tissue complication probability modelling in head and neck cancer patients receiving radiotherapy

MacRae, D. C., van der Hoek, L., de Vette, S. P. M., Neh, H., Moreno, A. C., Fuller, C. D., Langendijk, J. A., Valdenegro-Toro, M. A., Sijtsema, N. M., van Ooijen, P. M. A. & van Dijk, L. V., 17-Mar-2026, (E-pub ahead of print) In: Radiotherapy and Oncology. p. 111486

Research output: Contribution to journal › Article › Academic › peer-review

An evaluation of uncertainty quantification methods and measures for deep learning outcome prediction models in head and neck cancer radiotherapy

MacRae, D. C., van der Hoek, L., van Aalst, J. E., de Vette, S. P. M., van der Wal, R., Neh, H., Ma, B., Sijtsema, N. M., Valdenegro-Toro, M. A., van Ooijen, P. M. A. & van Dijk, L. V., May-2026, In: Physics and imaging in radiation oncology. 39, p. 100978

Research output: Contribution to journal › Article › Academic › peer-review

Dosimetric comparison of the shoulder region between paired photon and proton plans in breast cancer patients

Liang, Y., Verhoeven, K., Vilches-Freixas, G., Bosma, S. C. J., Canters, R., Froklage, F. E., Houben, R., Maduro, J. H., Overbosch, J., Penninkhof, J. J., Sattler, M. G. A., Simons, J. M., Sijtsema, N. M., Vliegenthart, R., Crijns, A. P. G., Rivera, S. & Boersma, L. J., Jun-2026, In: Technical Innovations and Patient Support in Radiation Oncology. 38, 6 p., 100393.

Research output: Contribution to journal › Article › Academic › peer-review

In response to Liu et al

de Vette, S. P. M., Langendijk, J. A., Sijtsema, N. M. & van Dijk, L. V., Mar-2026, In: Radiotherapy and Oncology. 216, 2 p., 111353.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Prediction of treatment outcome in nasopharyngeal carcinoma patients

Zhou, G., Sijtsema, N. M., Li, Y., Zhai, T., Xi, L., Li, J., van der Schaaf, A., van Dijk, L. V., Shi, Y., Yang, P. & Langendijk, J. A., Dec-2026, In: BMC Cancer. 26, 1, 11 p., 585.

Research output: Contribution to journal › Article › Academic › peer-review

2019 Integrating CT image features improves clinical prediction models for outcome in nasopharyngeal carcinoma patients treated with (chemo)radiation

Zhou, G., Ma, B., Li, Y., yang, P., Shi, Y., van der Schaaf, A., van Dijk, L. V., Langendijk, J. A. & Sijtsema, N. M., May-2025, In: Radiotherapy and Oncology. 206, p. S1010-S1011 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

2480 Towards a multi-toxicity NTCP modelling approach for head and neck cancer

MacRae, D., der Hoek, L. V., de Vette, S. P. M., Neh, H., van Ooijen, P. M. A., Sijtsema, N. M., Moreno, A. C., Fuller, C. D., Langendijk, J. A., Toro, M. V. & van Dijk, L. V., May-2025. 3 p.

Research output: Contribution to conference › Abstract › Academic

"AI tumor delineation for all breathing phases in early-stage NSCLC"

de la O Arevalo, L. R., Sijtsema, N. M., van Dijk, L. V., Langendijk, J. A., Wijsman, R. & van Ooijen, P. M. A., Oct-2025, In: Radiotherapy and Oncology. 211, 7 p., 111095.

Research output: Contribution to journal › Article › Academic › peer-review

Association between dose to cardiac structures and overall survival: A multivariable analysis in a large, multi-institutional database of stage III NSCLC patients with external validation

Garrett Fernandes, M., Bussink, J., Wijsman, R., Gouw, Z., Weiß, A., Sijtsema, N. M., Canters, R., Hope, A., De Ruysscher, D., Troost, E. G. C., Sonke, J. J., Stam, B. & Monshouwer, R., May-2025, In: Radiotherapy and Oncology. 206, 9 p., 110821.

Research output: Contribution to journal › Article › Academic › peer-review

Deep learning-based prediction of radiation pneumonitis in advanced stage lung cancer using average 4D CT, 3D dose, and lung segmentations

van der Wal, R., de la O Arevalo, L. R., van der Hoek, L., de Vette, S. P. M., Neh, H., MacRae, D. C., Langendijk, J. A., Sijtsema, N. M., van Ooijen, P., Wijsman, R. & van Dijk, L. V., May-2025, In: Radiotherapy and Oncology. 206, Supplement 1, p. S3784-S3786 3 p.

Research output: Contribution to journal › Meeting Abstract › Academic

All (165) publications

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dr. ir. N.M. (Marianna) Sijtsema

Research interests

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