J. (Joram) Mooiweer

PhD-studentHij/hem

Faculteit Medische Wetenschappen/UMCG

E-mail:

j.mooiweer umcg.nl

Research Portal

Publicaties

Gene expression profiling reveals enhanced nutrient and drug metabolism and maturation of hiPSC-derived intestine-on-chip relative to organoids and Transwells

Moerkens, R., Mooiweer, J., Smits, E., Berg, M., Ramírez-Sánchez, A. D., Modderman, R., Puschhof, J., Pleguezuelos-Manzano, C., Barrett, R. J., Wijmenga, C., Jonkers, I. H. & Withoff, S., 9-dec.-2025, In: Stem Cell Reports. 20, 12, 15 blz., 102715.

Onderzoeksoutput: Article › › peer review

Human organoids and organ-on-chips in coeliac disease research

Simpson, H. L., Smits, E., Moerkens, R., Wijmenga, C., Mooiweer, J., Jonkers, I. H. & Withoff, S., feb.-2025, In: Trends in Molecular Medicine. 31, 2, blz. 117-137 21 blz.

Onderzoeksoutput › peer review

An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells

Moerkens, R., Mooiweer, J., Ramírez-Sánchez, A. D., Oelen, R., Franke, L., Wijmenga, C., Barrett, R. J., Jonkers, I. H. & Withoff, S., 23-jul.-2024, In: Cell reports. 43, 7, 26 blz., 114247.

Onderzoeksoutput: Article › › peer review

Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

Onderzoeksoutput: Voordruk ›

Standardizing designed and emergent quantitative features in microphysiological systems

Nahon, D. M., Moerkens, R., Aydogmus, H., Lendemeijer, B., Martínez-Silgado, A., Stein, J. M., Dostanić, M., Frimat, J.-P., Gontan, C., de Graaf, M. N. S., Hu, M., Kasi, D. G., Koch, L. S., Le, K. T. T., Lim, S., Middelkamp, H. H. T., Mooiweer, J., Motreuil-Ragot, P., Niggl, E. & Pleguezuelos-Manzano, C., Puschhof, J., Revyn, N., Rivera-Arbelaez, J. M., Slager, J., Windt, L. M., Zakharova, M., van Meer, B. J., Orlova, V. V., de Vrij, F. M. S., Withoff, S., Mastrangeli, M., van der Meer, A. D. & Mummery, C. L., 2024, In: Nature biomedical engineering. 8, blz. 941–962 22 blz.

Onderzoeksoutput › peer review

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFN gamma Signaling in Celiac Disease

BIOS Consortium, van der Graaf, A., Zorro, M. M., Claringbould, A., Vosa, U., Aguirre-Gamboa, R., Li, C., Mooiweer, J., Ricano-Ponce, I., Borek, Z., Koning, F., Kooy-Winkelaar, Y., Sollid, L. M., Qiao, S.-W., Kumar, V., Li, Y., Franke, L., Withoff, S., Wijmenga, C. & Sanna, S., Jonkers, I., 25-jan.-2021, In: Frontiers in Genetics. 11, blz. 562434 16 blz., 562434.

Onderzoeksoutput: Article › › peer review

Celiac disease-on-chip: Modeling a multifactorial disease in vitro

Moerkens, R., Mooiweer, J., Withoff, S. & Wijmenga, C., 1-mei-2019, In: United European Gastroenterology Journal. 7, 4, blz. 467-476 10 blz.

Onderzoeksoutput › peer review

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation

Adam, I., Dewi, D. L., Mooiweer, J., Sadik, A., Mohapatra, S. R., Berdel, B., Keil, M., Sonner, J. K., Thedieck, K., Rose, A. J., Platten, M., Heiland, I., Trump, S. & Opitz, C. A., 2018, In: OncoImmunology. 7, 12, 14 blz., 1486353.

Onderzoeksoutput: Article › › peer review