J. (Joram) Mooiweer

PhD-studentHe/him

Faculty of Medical Sciences

E-mail:

j.mooiweer umcg.nl

ORCID Research Portal

Publications

Gene expression profiling reveals enhanced nutrient and drug metabolism and maturation of hiPSC-derived intestine-on-chip relative to organoids and Transwells

Moerkens, R., Mooiweer, J., Smits, E., Berg, M., Ramírez-Sánchez, A. D., Modderman, R., Puschhof, J., Pleguezuelos-Manzano, C., Barrett, R. J., Wijmenga, C., Jonkers, I. H. & Withoff, S., 9-Dec-2025, In: Stem Cell Reports. 20, 12, 15 p., 102715.

Research output: Contribution to journal › Article › Academic › peer-review

Human organoids and organ-on-chips in coeliac disease research

Simpson, H. L., Smits, E., Moerkens, R., Wijmenga, C., Mooiweer, J., Jonkers, I. H. & Withoff, S., Feb-2025, In: Trends in Molecular Medicine. 31, 2, p. 117-137 21 p.

Research output: Contribution to journal › Review article › peer-review

An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells

Moerkens, R., Mooiweer, J., Ramírez-Sánchez, A. D., Oelen, R., Franke, L., Wijmenga, C., Barrett, R. J., Jonkers, I. H. & Withoff, S., 23-Jul-2024, In: Cell reports. 43, 7, 26 p., 114247.

Research output: Contribution to journal › Article › Academic › peer-review

Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

Research output: Working paper › Preprint › Academic

Standardizing designed and emergent quantitative features in microphysiological systems

Nahon, D. M., Moerkens, R., Aydogmus, H., Lendemeijer, B., Martínez-Silgado, A., Stein, J. M., Dostanić, M., Frimat, J.-P., Gontan, C., de Graaf, M. N. S., Hu, M., Kasi, D. G., Koch, L. S., Le, K. T. T., Lim, S., Middelkamp, H. H. T., Mooiweer, J., Motreuil-Ragot, P., Niggl, E. & Pleguezuelos-Manzano, C., Puschhof, J., Revyn, N., Rivera-Arbelaez, J. M., Slager, J., Windt, L. M., Zakharova, M., van Meer, B. J., Orlova, V. V., de Vrij, F. M. S., Withoff, S., Mastrangeli, M., van der Meer, A. D. & Mummery, C. L., 2024, In: Nature biomedical engineering. 8, p. 941–962 22 p.

Research output: Contribution to journal › Review article › peer-review

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFN gamma Signaling in Celiac Disease

BIOS Consortium, van der Graaf, A., Zorro, M. M., Claringbould, A., Vosa, U., Aguirre-Gamboa, R., Li, C., Mooiweer, J., Ricano-Ponce, I., Borek, Z., Koning, F., Kooy-Winkelaar, Y., Sollid, L. M., Qiao, S.-W., Kumar, V., Li, Y., Franke, L., Withoff, S., Wijmenga, C. & Sanna, S., Jonkers, I., 25-Jan-2021, In: Frontiers in Genetics. 11, p. 562434 16 p., 562434.

Research output: Contribution to journal › Article › Academic › peer-review

Celiac disease-on-chip: Modeling a multifactorial disease in vitro

Moerkens, R., Mooiweer, J., Withoff, S. & Wijmenga, C., 1-May-2019, In: United European Gastroenterology Journal. 7, 4, p. 467-476 10 p.

Research output: Contribution to journal › Review article › peer-review

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation

Adam, I., Dewi, D. L., Mooiweer, J., Sadik, A., Mohapatra, S. R., Berdel, B., Keil, M., Sonner, J. K., Thedieck, K., Rose, A. J., Platten, M., Heiland, I., Trump, S. & Opitz, C. A., 2018, In: OncoImmunology. 7, 12, 14 p., 1486353.

Research output: Contribution to journal › Article › Academic › peer-review