Skip to ContentSkip to Navigation
About us Practical matters How to find us I. Manfredonia, MSc

Research interests

PhD project:  RNA secondary structures in the evolution of Flaviviruses

Thanks to their error-prone RNA polymerases, Flaviviruses exist in their hosts as genetically diversified populations of related genomes. In arthropod-borne flaviviruses (ssRNA+ viruses) which normally switch between arthropod and human hosts, the viral population is cyclically exposed to different and strong evolutionary forces. Among all the factors contributing to viral evolution, I’m interested in RNA secondary structures. 

Publications

Genome-scale deconvolution of RNA structure ensembles

RNA Post-Transcriptional Modification Mapping Data Analysis Using RNA Framework

Structure and regulation of coronavirus genomes: State-of-the-art and novel insights from SARS-CoV-2 studies

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

Read more