1. Cholangiopathy and biliary fibrosis in Cyp2c70-deficient mice are fully reversed by ursodeoxycholic acid

   de Boer, J. F., de Vries, H. D., Palmiotti, A., Li, R., Doestzada, M., Hoogerland, J. A., Fu, J., La Rose, A. M., Westerterp, M., Mulder, N. L., Hovingh, M. V., Koehorst, M., Kloosterhuis, N. J., Wolters, J. C., Bloks, V. W., Haas, J. T., Dombrowicz, D., Staels, B., van de Sluis, B. & Kuipers, F., 10-Dec-2020, In : Cellular and molecular gastroenterology and hepatology.

   Research output: Contribution to journal › Article › Academic › peer-review

2. A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

   de Boer, J. F., Verkade, E., Mulder, N. L., de Vries, H. D., Huijkman, N. C., Koehorst, M., Boer, T., Wolters, J. C., Bloks, V. W., van de Sluis, B. & Kuipers, F., Mar-2020, In : Journal of Lipid Research. 61, 3, p. 291-305 15 p.

   Research output: Contribution to journal › Article › Academic › peer-review

3. A HUMAN-LIKE COMPOSITION OF THE CIRCULATING BILE ACID POOL IMPACTS ON PLASMA LDL CHOLESTEROL IN MICE

   De Boer, J. F., de Vries, H. D., Palmiotti, A., Li, R., Mulder, N. L., Hovingh, M. V., Koehorst, M., Kloosterhuis, N. J., Bloks, V. W., van de Sluis, B. & Kuipers, F., Aug-2019, In : ATHEROSCLEROSIS. 287, p. E14-E14 1 p.

   Research output: Contribution to journal › Meeting Abstract › Academic

4. Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease

   van Zutphen, T., Bertolini, A., de Vries, H. D., Bloks, V. W., de Boer, J. F., Jonker, J. W. & Kuipers, F., 25-Jun-2019, Bile Acids and Their Receptors. Springer, p. 207-234 28 p. (Handbook of Experimental Pharmacology).

   Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

5. A humanized bile acid pool induced by somatic CRISPR/Cas9-mediated deletion of Cyp2c70 modulates effects of pharmacological FXR activation in mice

   de Boer, J. F., Verkade, E., Mulder, N. L., de Vries, H. D., Huijkman, N., Koehorst, M., Boer, T., Wolters, J. C., Bloks, V. W., van de Sluis, B. & Kuipers, F., Apr-2019, In : Journal of Hepatology. 70, p. E25-E26 2 p.

   Research output: Contribution to journal › Meeting Abstract › Academic

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