H.D. de Vries, MSc

Faculty of Medical Sciences

Telephone:

+31 50 361 1576

Campus Fryslan

Telephone:

E-mail:

h.d.de.vries rug.nl

Research Portal

Publications

Cholangiopathy and biliary fibrosis in Cyp2c70-deficient mice are fully reversed by ursodeoxycholic acid

de Boer, J. F. , de Vries, H. D. , Palmiotti, A. , Li, R. , Doestzada, M. , Hoogerland, J. A. , Fu, J. , La Rose, A. M. , Westerterp, M. , Mulder, N. L. , Hovingh, M. V. , Koehorst, M. , Kloosterhuis, N. J. , Wolters, J. C. , Bloks, V. W. , Haas, J. T. , Dombrowicz, D. , Staels, B. , van de Sluis, B. & Kuipers, F. , 2021 , In: Cellular and molecular gastroenterology and hepatology. 11 , 4 , p. 1045-1069 25 p.

Research output: Contribution to journal › Article › Academic › peer-review

Low production of 12 alpha-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70(-/-) mice by reducing fat absorption

Li, R. , Palmiotti, A. , de Vries, H. D. , Hovingh, M. V. , Koehorst, M. , Mulder, N. L. , Zhang, Y. , Kats, K. , Bloks, V. W. , Fu, J. , Verkade, H. J. , de Boer, J. F. & Kuipers, F. , 2021 , In: Journal of Lipid Research. 62 , 20 p. , 100134.

Research output: Contribution to journal › Article › Academic › peer-review

A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

de Boer, J. F. , Verkade, E. , Mulder, N. L. , de Vries, H. D. , Huijkman, N. C. , Koehorst, M. , Boer, T. , Wolters, J. C. , Bloks, V. W. , van de Sluis, B. & Kuipers, F. , Mar-2020 , In: Journal of Lipid Research. 61 , 3 , p. 291-305 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

A humanized bile acid pool induced by somatic CRISPR/Cas9-mediated deletion of Cyp2c70 modulates effects of pharmacological FXR activation in mice

de Boer, J. F. , Verkade, E. , Mulder, N. L. , de Vries, H. D. , Huijkman, N. , Koehorst, M. , Boer, T. , Wolters, J. C. , Bloks, V. W. , van de Sluis, B. & Kuipers, F. , Apr-2019 , In: Journal of Hepatology. 70 , p. E25-E26 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

A HUMAN-LIKE COMPOSITION OF THE CIRCULATING BILE ACID POOL IMPACTS ON PLASMA LDL CHOLESTEROL IN MICE

De Boer, J. F. , de Vries, H. D. , Palmiotti, A. , Li, R. , Mulder, N. L. , Hovingh, M. V. , Koehorst, M. , Kloosterhuis, N. J. , Bloks, V. W. , van de Sluis, B. & Kuipers, F. , Aug-2019 , In: ATHEROSCLEROSIS. 287 , p. E14-E14 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease

van Zutphen, T. , Bertolini, A. , de Vries, H. D. , Bloks, V. W. , de Boer, J. F. , Jonker, J. W. & Kuipers, F. , 25-Jun-2019 , (E-pub ahead of print) Bile Acids and Their Receptors. Springer , p. 207-234 28 p. (Handbook of Experimental Pharmacology).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

All (6) publications

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