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Publicaties

Bile Acid Detergency as Determinant of Liver Pathology in a Humanized Mouse Model of Progressive Familial Intrahepatic Cholestasis Type 3

Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70−/− mice

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition

Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids

Role of bile acid receptor FXR in development and function of brown adipose tissue

Cholangiopathy and biliary fibrosis in Cyp2c70-deficient mice are fully reversed by ursodeoxycholic acid

Low production of 12 alpha-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70(-/-) mice by reducing fat absorption

Low production of 12 alpha-hydroxylated bile acids prevents hepatic steatosis in mice with a human-like bile acid pool by reducing fat absorption

Sustainable Development Goals

SDG 3 – Goede gezondheid en welzijn

Meer informatie over de Sustainable Development Goals.