dr. G. (Gert) Luurtsema

Faculty of Medical Sciences

Telephone:

+31 50 361 3541

E-mail:

g.luurtsema umcg.nl

ORCID Research Portal

Research interests

The research of Gert Luurtsema, associate professor at the UMCG, is focused on a broad range of topics, ranging from tracer development to validation of clinical imaging applications. With support of NWO-STW funding, he has accomplished a research line on imaging of the blood-brain barrier (BBB) integrity in relation to brain disorders and drug delivery. Besides this, he is supervising > 7 PhD students, 5 master students and 3 postdocs. Currently, he is (co-)author of more than 100 peer-reviewed scientific articles in high ranking journals and scientific textbooks. He was guest editor of the journals Current Pharmaceutical Design and Contrast Media & Molecular Imaging.

Publications

One-pot synthesis of 6-l-[18f] fluoro-3,4-dihydroxyphenylalanine (6-l-[18f] fdopa).

Luurtsema, G., Kwizera, C., Blok, S. N., Farinha Antunes, I., Elsinga, P. H. & de Vries, E., 21-Mar-2024, Patent No. WO2024058665, 14-Sept-2023, Priority date 15-Sept-2022

Research output: Patent

[15O]H2O PET: Potential or Essential for Molecular Imaging?

Slart, R. H. J. A., Martinez-Lucio, T. S., Boersma, H. H., Borra, R. H., Cornelissen, B., Dierckx, R. A. J. O., Dobrolinska, M., Doorduin, J., Erba, P. A., Glaudemans, A. W. J. M., Giacobbo, B. L., Luurtsema, G., Noordzij, W., van Sluis, J., Tsoumpas, C. & Lammertsma, A. A., 26-Aug-2023, (E-pub ahead of print) In: Seminars in Nuclear Medicine.

Research output: Contribution to journal › Review article › peer-review

Cardiac PET Imaging of ATP Binding Cassette (ABC) Transporters: Opportunities and Challenges

Liu, W., Mossel, P., Schwach, V., Slart, R. H. J. A. & Luurtsema, G., 11-Dec-2023, In: Pharmaceuticals. 16, 12, 21 p., 1715.

Research output: Contribution to journal › Review article › peer-review

Effects of proton therapy on regional [18F]FDG uptake in non-tumor brain regions of patients treated for head and neck cancer

Arif, W. M., Elsinga, P. H., Steenbakkers, R. J. H. M., Noordzij, W., Barazzuol, L., Siang, K. N. G. W., Brouwer, C. L., Giacobbo, B. L., Dierckx, R. A. J. O., Borra, R. J. H. & Luurtsema, G., Sept-2023, In: Clinical and Translational Radiation Oncology. 42, 14 p., 100652.

Research output: Contribution to journal › Article › Academic › peer-review

Non-invasive kinetic modelling approaches for quantitative analysis of brain PET studies

van der Weijden, C. W. J., Mossel, P., Bartels, A. L., Dierckx, R. A. J. O., Luurtsema, G., Lammertsma, A. A., Willemsen, A. T. M. & de Vries, E. F. J., 2023, In: European Journal of Nuclear Medicine and Molecular Imaging. p. 1636–1650 15 p.

Research output: Contribution to journal › Review article › peer-review

Oral administration of PET tracers: Current status

Salvi de Souza, G., Mantovani, D. B. A., Mossel, P., Haarman, B. C. M., Silva, A. M. M. D., Boersma, H. H., Furini, C. R. G., Lammertsma, A. A., Tsoumpas, C. & Luurtsema, G., May-2023, In: Journal of Controlled Release. 357, p. 591-605 15 p.

Research output: Contribution to journal › Review article › peer-review

Quantification of P-glycoprotein function at the human blood-brain barrier using [ 18F]MC225 and PET.

Mossel, P., Arif, W. M., De Souza, G. S., Varela, L. G., van der Weijden, C. W. J., Boersma, H. H., Willemsen, A. T. M., Boellaard, R., Elsinga, P. H., Borra, R. J. H., Dierckx, R. A. J. O., Lammertsma, A. A., Bartels, A. L. & Luurtsema, G., Nov-2023, In: European Journal of Nuclear Medicine and Molecular Imaging. 50, p. 3917–3927 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Severely increased albuminuria in patients with type 2 diabetes mellitus is associated with increased subclinical atherosclerosis in femoral arteries with Na [18F]F activity as a proxy: The DETERMINE study

Reijrink, M., Sluiter, J. K. E., te Velde-Keyzer, C. A., de Borst, M. H., van Praagh, G. D., Greuter, M. J. W., Luurtsema, G., Boersma, H. H., Pol, R. A., Hillebrands, J. L., van Dijk, P. R., Hoogenberg, K., Mulder, D. J. & Slart, R. H. J. A., 29-Jul-2023, (Accepted/In press) In: Atherosclerosis. 7 p., 117199.

Research output: Contribution to journal › Article › Academic › peer-review

A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

Helbert, H., Ploeg, E. M., Samplonius, D. F., Blok, S. N., Antunes, I. F., Böhmer, V. I., Luurtsema, G., Dierckx, R. A. J. O., Feringa, B. L., Elsinga, P. H., Szymanski, W. & Helfrich, W., 3-Mar-2022, In: EJNMMI Radiopharmacy and Chemistry. 7, 1, 11 p., 3.

Research output: Contribution to journal › Article › Academic › peer-review

Dose-response assessment of cerebral P-glycoprotein inhibition in vivo with [ 18 F]MC225 and PET

Garcia Varela, L., Mossel, P., Aguiar, P., Vazquez-Matias, D., van Waarde, A., Willemsen, A., Bartels, A. L., Colabufo, N. A., Dierckx, R., Elsinga, P. H. & Luurtsema, G., 1-Jul-2022, In: Journal of Controlled Release. 347, p. 500-507 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (135) publications

Press/media

Diagnosi di malattie cerebrali oggi se ne parla a Triggiano

Gert Luurtsema

17/02/2020

Press/Media: Expert Comment › Academic

Diagnose van prostaatkanker bij Treant op topniveau

Gert Luurtsema

08/05/2019

Press/Media: Expert Comment › Academic

All (2) press/media

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