prof. dr. G.H. (Truuske) de Bock

Professor of Oncological Epidemiology

Faculty of Medical Sciences

Telephone:

+31 6 5525 6940

E-mail:

g.h.de.bock umcg.nl

Homepage ORCID Research Portal

Research interests

The research of Geertruida de Bock is about the early detection of cancer and improvement of outcomes after cancer treatment. To evaluate this in a systematic way, she set up an UMCG’s oncology databiobank OncoLifeS with quality of life as a main outcome. To assess and optimize screening strategies, she works on defining which populations are at risk of cancer and negative outcomes. She does not only consider benefits of screening and treatment, but also the negative effects of over-diagnosis, tumor-induction, false-positive results, and side-effects. Systematic literature reviews, analysis of cohorts and modelling are the most important methods she uses.

Publications

Influence of follow-up, screening age, interval, and compliance on overdiagnosis of ductal carcinoma in situ (DCIS): A modelling study

Poelhekken, K., Greuter, M. J. W., Dorrius, M. D. & de Bock, G. H., 2026, In: PLoS ONE. 21, 1, p. e0331821

Research output: Contribution to journal › Article › Academic › peer-review

Outcomes for ER-positive CHEK2 c.1100delC breast cancer patients compared with breast cancer patients without the variant

HEBON, Schreurs, M. A. C., Adank, M. A., Heemskerk-Gerritsen, B. A. M., Hollestelle, A., Smallenbroek, N., van Asperen, C. J., Ausems, M. G. E. M., van de Beek, I., de Bock, G. H., Boere, I., van Hest, L. P., van Kaam, K. J. A. F., de Munck, L., Vos, J. R., Jager, A., Schmidt, M. K. & Hooning, M. J., Feb-2026, In: Breast. 85, 8 p., 104666.

Research output: Contribution to journal › Article › Academic › peer-review

Trends in cervical cancer incidence in the Netherlands: A join-point and age–period–cohort analysis (1989–2023)

Castañeda, K. M., Vermeulen, K. M., van der Aa, M., Schuuring, E., Wisman, G. B. A. & de Bock, G. H., 1-Jan-2026, In: International Journal of Cancer. 158, 1, p. 39-44 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Advancing Ki67 hotspot detection in breast cancer: a comparative analysis of automated digital image analysis algorithms

Zwager, M. C., Yu, S., Buikema, H. J., de Bock, G. H., Ramsing, T. W., Thagaard, J., Koopman, T. & van der Vegt, B., Jan-2025, In: Histopathology. 86, 2, p. 204-213 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Artificial intelligence as an independent reader of risk-dominant lung nodules: influence of CT reconstruction parameters

Mao, Y., Heuvelmans, M. A., van Tuinen, M., Yu, D., Yi, J., Oudkerk, M., Ye, Z., de Bock, G. H. & Dorrius, M. D., 29-Aug-2025, (E-pub ahead of print) In: European Radiology. 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

GEMO Study Collaborators, Lawrenson, K., Kar, S., McCue, K., Kuchenbaeker, K., Michailidou, K., Tyrer, J., Beesley, J., Ramus, S. J., Li, Q., Delgado, M. K., Lee, J. M., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Bandera, E. V. & Barile, M., Barkardottir, R. B., Barrowdale, D., Beckmann, M. W., Benitez, J., Berchuck, A., Bisogna, M., Bjorge, L., Blomqvist, C., Blot, W., Bogdanova, N., Bojesen, A., Bojesen, S. E., Bolla, M. K., Bonanni, B., Børresen-Dale, A.-L., Brauch, H., Brennan, P., Brenner, H., Bruinsma, F., Brunet, J., Buhari, S. A., Burwinkel, B., Butzow, R., Buys, S. S., Cai, Q., Caldes, T., Campbell, I., Cannioto, R. & Chang-Claude, J., 8-Sept-2025, In: Nature Communications. 16, p. 8237

Research output: Contribution to journal › Erratum

Authors' Reply “Non-Smoking and Non-Drinking Oral Cancer Patients Are at Higher Risk of Second Primary Tumours”

van der Aa, P. J. P., Witjes, M. J. H., van der Vegt, B., Schuuring, E., Boeve, K., Sidorenkov, G., de Bock, G. H. & de Visscher, S. A. H. J., Oct-2025, In: Oral diseases. 31, 10, p. 2970-2971 2 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Change in Metabolic Markers and the Risk of Skin Cancer: Results from the Lifelines Cohort Study in the Netherlands

Shimelash, M., Sidorenkov, G., van der Vegt, B., Jalving, M., Rácz, E. & de Bock, G. H., 1-Apr-2025, In: Cancer Epidemiology, Biomarkers & Prevention. 34, 4, p. 598–609 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Changes in global quality of life after treatment with immune checkpoint inhibitors in patients receiving different treatment regimens for advanced stage lung cancer in the Netherlands: a 2015-2021 cohort study

Malhotra, A., Suazo-Zepeda, E., Vinke, P. C., de Bock, G. H., Maas, W. J., Hiltermann, J. T. J. N., Rachet, B., Leyrat, C. & Quaresma, M., 20-Feb-2025, In: BMJ Open. 15, 2, 12 p., e098062.

Research output: Contribution to journal › Article › Academic › peer-review