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About us Practical matters How to find us dr. F.J. (Frank) Dekker

dr. F.J. (Frank) Dekker

Associate professor Pharmaceutical Epigenetics
Profile picture of dr. F.J. (Frank) Dekker
Telephone:
+31 6 3192 1118 (00316 3192 1118)
E-mail:
f.j.dekker rug.nl

Publications

Defining the Catalytic Boundaries of N-Nitrosourea-Forming StzF/SznF and Related Metalloenzymes through Genome Mining and Mechanistic Analysis

Development of Indole-3-yl-methylene-thiobarbital Derivatives as Inhibitors of HDAC8 Enzyme Activity

Discovery of Furan-2-Carboxylic Acid Derivatives as Novel D-Dopachrome Tautomerase (D-DT) and Macrophage Migration Inhibitory Factor-1 (MIF-1) Dual Inhibitors

Fasting disrupts the InsP₆-HDAC3 axis to drive ER stress-mediated clearance of DNA-damaged cells and enforce tissue quality control

Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma

Correction to “Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells”Article link copied!

Novel 15-lipoxygenase-1 inhibitor protects cells from RSL3-induced cell death

Changes in histone lysine acetylation, but not DNA methylation during facultative hibernation in Syrian hamster liver

Exploration of Hydrazide-Based HDAC8 PROTACs for the Treatment of Hematological Malignancies and Solid Tumors

Impact of HDAC inhibitors on macrophage polarization to enhance innate immunity against infections

Press/media

Finalisten van ‘Life Science Innovation Award’ zijn bekend

University of Groningen: Open Competition Science-M Grants For Krushynska And Dekker

Financiering voor ontwikkeling van innovatieve inhalatietherapie voor COPD-patiënten

Sustainable Development Goals

SDG 3 - Good Health and Well-being

More information about the Sustainable Development Goals.