prof. dr. B.J.L. (Bart) Eggen

Professor

Faculty of Medical Sciences

Telephone:

E-mail:

b.j.l.eggen umcg.nl

Homepage ORCID Research Portal

Publications

Brain extracellular matrix: Novel decellularization protocols for thin rat and human brain tissue slices

de Jong, J. M., Werkman, I. L., Kats, K., Bosma, J., Kooistra, S. M., Eggen, B. J. L. & Baron, W., Mar-2026, In: Heliyon. 12, 4, 12 p., e44653.

Research output: Contribution to journal › Article › Academic › peer-review

Increased Tumor Necrosis Factor Superfamily Members in Neuroinflammatory Schizophrenia and Bipolar Disorder Midbrains

Mendez-Victoriano, G., Zhu, Y., Neuhaus, L., Shaik, S., Middleton, F., Kondo, Y., Fayyazuddin, A., Hoeppner, D., Puvogel, S., Alsema, A., Kracht, L., Matsumoto, M., Eggen, B. J. L., Walker, A. K., Webster, M. J., Sommer, I. E. C. & Weickert, C. S., Mar-2026, In: Biological Psychiatry Global Open Science. 6, 2, 13 p., 100650.

Research output: Contribution to journal › Article › Academic › peer-review

Midbrain microglial and macrophage mRNAs distinguish neuroinflammatory schizophrenia from bipolar disorder

Mendez-Victoriano, G., Zhu, Y., Kostoglou, Y., Walker, A. K., Middleton, F., Massa, P. T., Eggen, B. J. L., Webster, M. J., Sommer, I. E. C. & Weickert, C. S., May-2026, In: Brain, Behavior, and Immunity. 134, 17 p., 106276.

Research output: Contribution to journal › Article › Academic › peer-review

Beyond the nuclear border: single-cell analysis of in situ sequenced human brain tissue using cellular features

Kotah, J. M., Rust, T., van Weering, H. R. J., Bosma, J., Woudstra, A. L., Kooistra, S. M. & Eggen, B. J. L., 22-Jul-2025, In: Communications biology. 8, 1, 12 p., 1089.

Research output: Contribution to journal › Article › Academic › peer-review

Calorie restriction increases the sensitivity of progeroid Ercc1Δ/− mice to acute (neuro)inflammation

Reitsema, V. A., Schreuder, L., Gerrits, E., Eggen, B. J. L., Goris, M., Laman, J. D., de Rooij, S. E., Wesseling, E. M., Bouma, H. R. & Henning, R. H., Apr-2025, In: GeroScience. 47, p. 1641–1652 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Microglia endotoxin tolerance is retained after enforced repopulation

Medeiros-Furquim, T., Miedema, A., Schilder, E., Brouwer, N., Holtman, I. R., Kooistra, S. M. & Eggen, B. J. L., Aug-2025, In: Brain, Behavior, and Immunity. 128, p. 512-528 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

Matera, A., Compagnion, A. C., Pedicone, C., Kotah, J. M., Ivanov, A., Monsorno, K., Labouèbe, G., Leggio, L., Pereira-Iglesias, M., Beule, D., Mansuy-Aubert, V., Williams, T. L., Iraci, N., Sierra, A., Marro, S. G., Goate, A. M., Eggen, B. J. L., Kerr, W. G. & Paolicelli, R. C., 14-Jan-2025, In: Immunity. 58, 1, p. 197-217.e13 35 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5

Montilla, A., Zabala, A., Calvo, I., Bosch-Juan, M., Tomé-Velasco, I., Mata, P., Koster, M., Sierra, A., Kooistra, S. M., Soria, F. N., Eggen, B. J. L., Fresnedo, O., Fernández, J. A., Tepavcevic, V., Matute, C. & Domercq, M., 25-Mar-2025, In: Cellular and molecular life sciences. 82, 21 p., 131.

Research output: Contribution to journal › Article › Academic › peer-review

Schizophrenia-associated changes in neuronal subpopulations in the human midbrain

Alsema, A. M., Puvogel, S., Kracht, L., Webster, M. J., Weickert, C. S., Eggen, B. J. L. & Sommer, I. E. C., 1-Apr-2025, In: Brain. 148, 4, p. 1374-1388 15 p.

Research output: Contribution to journal › Article › Academic › peer-review