A. Felzen

Telephone:

E-mail:

a.felzen umcg.nl

Research interests

Cholestatic liver disease with a focus on progressive familial intrahepatic cholestasis (PFIC) and primary sclerosing cholangitis (PSC).

Publications

EASL Clinical Practice Guidelines on genetic cholestatic liver diseases

European Association for the Study of the Liver, Aug-2024, In: Journal of Hepatology. 81, 2, p. 303-325 23 p.

Research output: Contribution to journal › Article › Academic › peer-review

The spectrum of Progressive Familial Intrahepatic Cholestasis diseases: Update on pathophysiology and emerging treatments

Felzen, A. & Verkade, H. J., Nov-2021, In: European journal of medical genetics. 64, 11, 8 p., 104317.

Research output: Contribution to journal › Review article › peer-review

Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency

NAtural course and Prognosis of PFIC and Effect of biliary Diversion (NAPPED) Consortium, Felzen, A., van Wessel, D. B. E., Gonzales, E., Thompson, R. J., Jankowska, I., Shneider, B. L., Sokal, E., Grammatikopoulos, T., Kadaristiana, A., Jacquemin, E., Spraul, A., Lipiński, P., Czubkowski, P., Rock, N., Shagrani, M., Broering, D., Nicastro, E., Kelly, D. & Nebbia, G.& 53 others, Arnell, H., Fischler, B., Hulscher, J. B. F., Serranti, D., Arikan, C., Polat, E., Debray, D., Lacaille, F., Goncalves, C., Hierro, L., Muñoz Bartolo, G., Mozer-Glassberg, Y., Azaz, A., Brecelj, J., Dezsőfi, A., Calvo, P. L., Grabhorn, E., Hartleif, S., van der Woerd, W. J., Kamath, B. M., Wang, J.-S., Li, L., Durmaz, Ö., Kerkar, N., Jørgensen, M. H., Fischer, R., Jimenez-Rivera, C., Alam, S., Cananzi, M., Laverdure, N., Ferreira, C. T., Ordoñez Guerrero, F., Wang, H., Sency, V., Kim, K. M., Chen, H.-L., de Carvalho, E., Fabre, A., Bernabeu, J. Q., Zellos, A., Alonso, E. M., Sokol, R. J., Suchy, F. J., Loomes, K. M., McKiernan, P. J., Rosenthal, P., Turmelle, Y., Horslen, S., Schwarz, K., Bezerra, J. A., Wang, K., Hansen, B. E. & Verkade, H., Feb-2023, In: JHEP reports : innovation in hepatology. 5, 2, 12 p., 100626.

Research output: Contribution to journal › Article › Academic › peer-review

Axonal Regeneration in Cross-Face Nerve Grafts - Do Axon Counts Decline Over Time?

Felzen, A., Millesi, E., Robertson, C. E., Gibreel, W. & Mardini, S., 17-Jan-2025.

Research output: Contribution to conference › Poster › Academic

Een man met een gezwollen knie

Felzen, A., Rolink, R. & Bulthuis, G. J., 1-May-2024, In: Nederlands Tijdschrift voor Geneeskunde. 168, 2 p., D8109.

Research output: Contribution to journal › Letter › Professional

Analysis of long-term treatment effects of odevixibat on clinical outcomes in children with progressive familial intrahepatic cholestasis in odevixibat clinical studies vs external controls from the NAPPED database

Hansen, B., Valcheva, V., Yu, Q., Wessel, D. V., Thompson, R., Gonzalès, E., Jankowska, I., Sokal, E., Grammatikopoulos, T., Kadaristiana, A., Jacquemin, E., Spraul, A., Lipiński, P., Czubkowski, P., Rock, N., Shagrani, M., Kumar, K., Alkuraya, F., Sateesh, M. & Broering, D. C.& 32 others, Nicastro, E., Kelly, D., Nebbia, G., Arnell, H., Fischler, B., Serranti, D., Arıkan, C., Polat, E., Debray, D., Lacaille, F., Gonçalves, C., Llanillo, L. H., Bartolo, G. M., Mozer-Glassberg, Y., Azaz, A., Brecelj, J., Dezsőfi, A., Calvo, P. L., Grabhorn, E., Sturm, E., Woerd, W. L. V. D., Kamath, B. M., Wang, J.-S., Liting, L., Durmaz, O., Önal, Z., Felzen, A., Nomden, M., Sonajalg, J., Stein, P., Ni, Q. & Verkade, H., Jun-2023, p. S969-S970. 2 p.

Research output: Contribution to conference › Poster › Academic

Characterization of a novel bile salt export pump deficiency mouse model with the p.E297g mutation

Felzen, A., Hovingh, M., Havinga, R., Mulder, N., Koehorst, M., van de Sluis, B., de Boer, J. F., Kuipers, F. & Verkade, H., Jun-2023, ESPGHAN 55th Annual Meeting Abstracts. Wolters Kluwer, Vol. 76. p. 671-672 2 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

THE PRESENCE OF A TRUNCATING MUTATION IN ABCB11 ABROGATES THE BENEFICIAL EFFECT OF A RESIDUAL FUNCTION MUTATION ON THE COURSE OF SEVERE BILE SALT EXPORT PUMP DEFICIENCY

Felzen, A., van Wessel, D., Thompson, R. J., Gonzales, E. M., Jankowska, I., Shneider, B. L., Sokal, E., Grammatikopoulos, T., Kadaristiana, A., Jacquemin, E., Spraul, A., Lipinski, P., Czubkowski, P., Rock, N., Shagrani, M., Broering, D., Algoufi, T., Mazhar, N., Nicastro, E. & Kelly, D.& 53 others, Nebbia, G., Arnell, H., Fischler, B., Hulscher, J., Serranti, D., Arikan, C., Polat, E., Debray, D., Lacaille, F., Goncalves, C., Hierro, L., Bartolo, G. M., Mozer-Glassberg, Y., Azaz, A., Brecelj, J., Dezsofi, A., Calvo, P. L., Grabhorn, E., Hartleif, S., Van der Woerd, W., Kamath, B. M., Wang, J.-S., Li, L., Durmaz, O., Kerkar, N., Jorgensen, M. H., Fischer, R. T., Jimenez-Rivera, C., Alam, S., Cananzi, M., Ruiz, M., Ferreira, C. T., Ferrero, F. O., Wang, H., Sency, V., Kim, K. M., Chen, H.-L., Carvalho, E., Fabre, A., Bernabeu, J. Q., Alonso, E. M., Sokol, R. J., Suchy, F. J., Loomes, K. M., McKiernan, P. J., Rosenthal, P., Turmelle, Y., Horslen, S. P., Schwarz, K. B., Bezerra, J. A., Wang, K. S., Hansen, B. E. & Verkade, H. J., Nov-2020, In: Hepatology. 72, p. 884A-886A 3 p.

Research output: Contribution to journal › Meeting Abstract › Academic

All (8) publications

Press/media

Antonia Felzen awarded the Alex Mowat Prize 2023

Felzen, A.

29/05/2023

Press/Media: Research › Academic

Toekenningen KNAW Ter Meulen Beurs 2023

Felzen, A.

29/06/2023

Press/Media: Research › Professional

All (2) press/media

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