
EC:1.6.5.3
NADH-Q1-oxidoreductase (complex 1)
Mitochondrial complex I (NADH-ubiquinone reductase; EC 1.6.5.3) is the first multimeric complex of the respiratory chain that catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mammalian mitochondrial complex I is an assembly of at least 43 different subunits. Seven of the subunits are encoded by the mitochondrial genome; the remainder are the products of nuclear genes.
Benodigd materiaal : Fibroblasten
Last modified: | 23 February 2015 4.55 p.m. |