Dissertations

Khan AA.
Regulation of metabolizing enzymes and transporters for drugs and bile salts in human and rat intestine and liver. A study with precision-cut slices, 2010.
Promotor: Prof. dr. G.M.M. Groothuis.
Promotion date: 18 december 2009
ISBN: ISBN printed version: 97 8903674048-7
Electronic version of Dissertation 

Temming K.
New ways in RGD-peptide mediated drug targeting to angiogenic endothelium: on the nature of drugs, linkers, and carriers, 2007.
Promotores: Prof. dr. K. Poelstra
Co-promotor: Dr. R.J. Kok.
Promotion date: 26 oktober 2007
ISBN: ISBN printed version: 978-90-812125-2-6 ; ISBN electronic version: 978-90-812125-1-9
Electronic version of Dissertation

van de Kerkhof EG.
Drug metabolism in human and rat intestine: An in vitro approach, 2007.
Promotores: Prof. dr. G.M.M. Groothuis and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. ir. I.A.M. de Graaf.
Promotion date: 29 juni 2007
ISBN: ISBN printed version: 90-367-3046-4 ; ISBN electronic version: 90-367-3047-1
Electronic version of Dissertation

Tuin A.
Detoxification of LPS by alkaline phosphatase: application of a new concept in sepsis and inflammatory bowel disease, 2007.
Promotores: Prof. dr. K. Poelstra and Prof. dr. D.K.F. Meijer.
Promotion date: 11 mei 2007
ISBN: ISBN printed version: 9789036729932 ; ISBN electronic version: 9789036729949
Electronic version of Dissertation

Adrian JE.
Addressing liver fibrosis with lipid-based drug carriers targeted to hepatic stellate cells, 2006.
Promotores: Prof. dr. K. Poelstra, Prof. dr. G.L. Scherphof and Prof.dr. D.K.F. Meijer
Co-promotor: Dr. J.A.A.M. Kamps.
Promotion date: 6 december 2006
ISBN: ISBN printed version: 90-367-2858-4 ; ISBN electronic version: 90-367-2859-2
Electronic version of Dissertation

Hagens WI .
Arming drug carriers to disable the Hepatic Stellate Cell: The targeted delivery of apoptosis-inducing drugs to the fibrotic liver, 2006.
Promotores: Prof. dr. K. Poelstra and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. L. Beljaars.
Promotion date: 17 november 2006
ISBN: ISBN printed version: 90-367-2764-2 ; ISBN electronic version: 90-367-2765-0
Electronic version of Dissertation

Martignoni M.
Species and strain differences in drug metabolism in liver and intestine, 2006.
Promotor: Prof. dr. G.M.M. Groothuis
Co-promotor: Dr. R. de Kanter.
Promotion date: 30 oktober 2006
ISBN: ISBN printed version: 90-367-2713-8
Electronic version of Dissertation

Prakash J.
Renal-specific delivery of antifibrotic drugs using lysozyme. A novel approach for the treatment of renal fibrosis, 2006.
Promotores: Prof. dr. K. Poelstra and Prof. dr. D.K.F. Meijer
Co-promotores: Dr. R.J. Kok and Dr. F. Moolenaar.
Promotion date: 27 oktober 2006
ISBN: ISBN printed version: 90-367-2767-7 ; ISBN electronic version: 90-367-2768-5
Electronic version of Dissertation

Gonzalo Lázaro T.
A potential strategy to treat liver fibrosis: Drug targeting to hepatic stellate cells applying a novel linker technology, 2006.
Promotores: Prof. dr. K. Poelstra and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. R.J. Kok.
Promotion date: 29 september 2006
ISBN: ISBN printed version: 90-367-2720-0 ; ISBN electronic version: 90-367-2754-5
Electronic version of Dissertation

van de Bovenkamp M.
Liver fibrosis in vitro: Liver slices as a promising alternative, 2006.
Promotores: Prof. dr. G.M.M. Groothuis and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. P. Olinga.
Promotion date: 22 september 2006
ISBN: ISBN printed version: 90-9020963-8
Electronic version of Dissertation

Greupink AH.
The hepatic stellate cell in sight: targeting antiproliferative drugs to the fibrotic liver, 2006.
Promotores: Prof. dr. K. Poelstra and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. L. Beljaars.
Promotion date: 23 juni 2006
ISBN: ISBN printed version: 90-367-2589-5 ; ISBN electronic version: 90-367-2590-9
Electronic version of Dissertation

Rachmawati H.
The design of a liver-selective form of interleukin-10: a new strategy for the treatment of liver fibrosis, 2005.
Promotores: Prof. dr. K. Poelstra and Prof. dr. D.K.F. Meijer
Referent: dr. L. Beljaars.
Promotion date: 6 juni 2005
ISBN: ISBN printed version: 90-367-2272-1
Electronic version of Dissertation

Yan X.
Liposome-hepatocyte interactions. The role of plasma proteins, 2005.
Promotores: Prof. Dr. G.L. Scherphof, Prof. Dr. D.K.F. Meijer and Prof. Dr. K. Poelstra
Co-promotor: Dr. J.A.A.M. Kamps.
Promotion date: 23 februari 2005
ISBN: ISBN printed version: 90-367-2218-7

Bartsch M.
Targeted in vivo delivery of nucleic acods by lipid-based carriers, 2005.
Promotores: Prof. dr. G.L. Scherphof and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. J.A.A.M. Kamps.
Promotion date: 23 februari 2005
ISBN: ISBN printed version: 90-367-2213-6

Schoemaker MH.
Apoptotic cell death as a target for the treatment of acute and chronic liver injury, 2004.
Promotores: Prof. Dr. P.L.M. Jansen and Prof. Dr. H.J. Haisma
Co-promotores: Dr. H. Moshage and Dr. K. Poelstra.
Promotion date: 28 april 2004
ISBN: ISBN printed version: 90-6464-914-6
Electronic version of Dissertation

Kapojos JJ.
Response of endothelial and mesangial cells to proinflammatory stimuli. Regulation and activation of hemopexin and alkaline phosphatase, 2003.
Promotor: Prof. dr. W. Timens
Co-promotores: Dr. W.W. Bakker and Dr. K. Poelstra.
Promotion date: 10 december 2003

Schraa AJ.
RGD-modified proteins to target a (v) b (3) on tumor vasculature, 2002.
Promotores: Prof. dr. L.F.M.H. de Leij and Prof. dr. D.K.F. Meijer
Co-promotor: Dr. G. Molema.
Promotion date: 18 december 2002
ISBN: 90-367-1669-1

Bentala H.
Effect of alkaline phosphatase administration to mice with sepsis: exploration of a new strategy to detoxify endotoxin, 2002.
Promotor: Prof.Dr. D.K.F. Meijer
Co-promotor: Dr. K. Poelstra.
Promotion date: 25 oktober 2002

Everts M.
Selective delivery of dexamethasone to inflamed endothelium via E-selectin, 2002.
Promotores: Prof.dr. D.K.F. Meijer and Prof.dr. L.F.M.H. de Leij
Co-promotor: Dr. G. Molema.
Promotion date: 14 juni 2002

de Kanter R.
Human and rat organ slices: a tool to study drug metabolism and toxicity, 2002.
Promotor: Prof.dr. D.K.F. Meijer
Co-promoter: Dr. G.M.M. Groothuis.
Promotion date: 17 mei 2002
Electronic version of Dissertation