Netherlands Genomics Intitiative (NGI)

GBB is tightly associated to several activities within the Netherlands Genomics Initiative that started to develop since 2002. At present GBB staff is involved in the research programs of 4 NGI centres of which 2 are so-called Genomics Centre of Excellence (i.e. the Kluyver Centre for Industrial Fermentation and the Centre for Biosystems Genomics) and 2 Enabling Technology Centres (i.e. the Netherlands Proteomics Centre and the Netherlands Bioinformatics Centre.

1. Kluyver Centre for Industrial Fermentation

The Kluyver Centre employs microbial genomics to improve microorganisms for use in industrial fermentation processes. Fermentation is used in the production, from renewable feedstocks, of food products and ingredients, beverages, pharmaceutical compounds, nutraceuticals, and fine and bulk chemicals. The research covers five programmes: Yeast for chemicals, fuels and beverages, Filamentous fungi for proteins and peptides, Lactic acid bacteria for fermented foods and food ingredients, Systems biology of industrial micro-organisms and Industrial genomics for society.

Principal GBB scientists: Prof.dr. I.J. van der Klei (theme: yeasts for chemicals, fuels and beverages), Prof.dr. O.P. Kuipers (themes: lactic acid bacteria for fermented foods and ingredients and systems biology of industrial microorganisms), Prof.dr. A.J.M. Driessen (theme: filamentous fungi for proteins and peptides)

Kluyver Centre Website: http://www.kluyvercentre.nl/

2. Centre for Biosystems Genomics (CBSG)

The Centre for BioSystems Genomics is a consortium of major Dutch and international companies and top plant scientists working on potato, tomato, Arabidopsis and Brassica. It is a unique public-private partnership in plant genomics involving universities, research institutes, (inter)national companies and branch organisations that are active in potato, tomato and Brassica research and exploitation.

Principal GBB scientists and staff: Prof.dr. R.C. Jansen (Bioinformatics & Genetical genomics), Dr. E.G. Vrieling (Management affairs)

CBSG Website: http://www.cbsg.nl/

3. Netherlands Proteomics Centre

The Netherlands Proteomics Centre (NPC) is a strategic collaboration of research groups from six universities, four academic medical centres and several biotech companies. With a scientific programme addressing key areas of proteomics in several projects and several dedicated 'research hotels', the NPC performs high-quality research and knowledge transfer in an international context.

Through NPC Theme 3 Proteome Biology of Microorganisms (coordinated by Profs. B. Poolman and P. Verheart) GBB is involved to establish time-resolved (progression through cell cycles) and space resolved (organellar and cell type resolution) proteomics in yeast and to integrate proteomics and peptidomics in the elucidation of protein turnover and the discovery of secreted peptides in fungi. At GBB also one of the so-called NPC Research Hotels (i.e. the Membrane Proteomics Facility) is housed and facilitates collaborative research within NPC (e.g. for studying yeast nuclear proteomics together with Dr. L.M. Veenhoff at ERIBA, RUG) and external partners.

Principal GBB scientists: Prof.dr. B. Poolman (Theme leader and leader NPC Research Hotel Groningen), Dr. F. Fusetti (PI NPC Research Hotel Groningen), Prof.dr. I.J. van der Klei (PI Organelle and membrane proteomics).

NPC Website: http://www.netherlandsproteomicscentre.nl/

4. Netherlands Bioinformatics Centre

The Netherlands Bioinformatics Centre (NBIC), active since 2003, is a collaborative institute of the bioinformatics research groups in the Netherlands. Together, these groups perform cutting-edge research, develop novel tools and support platforms, create an e-science infrastructure, and educate the next generations of bioinformaticians.

Principal GBB scientists: Prof.dr. R.C. Jansen (Bioinformatics), Dr. E.G. Vrieling (Management affairs)

NBIC Website: http://www.nbic.nl/