Publications

Kosir, T., Das, H., Pedersen, M. P., Richard, A.-K., Anteghini, M., Martins Dos Santos, V., Oeljeklaus, S., van der Klei, I. J., & Warscheid, B. (2025). Integrative Omics reveals changes in the cellular landscape of peroxisome-deficient pex3 yeast cells. Microbial Cell, 12(1), 9-33. https://doi.org/10.15698/mic2025.02.842

Zerbes, R. M., Colina-Tenorio, L., Bohnert, M., von der Malsburg, K., Peikert, C. D., Mehnert, C. S., Perschil, I., Klar, R. F. U., de Boer, R., Kram, A., van der Klei, I., Oeljeklaus, S., Warscheid, B., Rampelt, H., & van der Laan, M. (2025). Coordination of cytochrome bc1 complex assembly at MICOS. Embo Reports, 26, 353-384. https://doi.org/10.1038/s44319-024-00336-x

Chen, H., de Boer, R., Krikken, A. M., Wu, F., & van der Klei, I. (2024). Hansenula polymorpha cells lacking the ER-localized peroxins Pex23 or Pex29 show defects in mitochondrial function and morphology. Open Biology, 13(5), Article bio060271. https://doi.org/10.1242/bio.060271

Jansen, R. L. M., de Boer, R., de Lange, E. M. F., Koster, J., Vlijm, R., Waterham, H. R., & van der Klei, I. J. (2024). Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells. Biochimica et Biophysica Acta - Molecular Cell Research, 1871(6), Article 119754. https://doi.org/10.1016/j.bbamcr.2024.119754

de Lange, E. M. F., Mol, F. N., van der Klei, I. J., & Vlijm, R. (2024). STED super-resolution microscopy unveils the dynamics of Atg30 on yeast Pex3-labeled peroxisomes. Iscience, 27(8), Article 110481. https://doi.org/10.1016/j.isci.2024.110481

Pedersen, M. P., Wolters, J. C., de Boer, R., Krikken, A. M., & van der Klei, I. J. (2024). The Hansenula polymorpha mitochondrial carrier family protein Mir1 is dually localized at peroxisomes and mitochondria. Biochimica et Biophysica Acta - Molecular Cell Research, 1871(5), Article 119742. https://doi.org/10.1016/j.bbamcr.2024.119742

Wu, F., de Boer, R., & van der Klei, I. J. (2023). Gluing yeast peroxisomes - composition and function of membrane contact sites. Journal of Cell Science, 136(11), Article 259440. https://doi.org/10.1242/jcs.259440

Jansen, R. L. M., van den Noort, M., Krikken, A. M., Bibi, C., Böhm, A., Schuldiner, M., Zalckvar, E., & van der Klei, I. J. (2023). Novel targeting assay uncovers targeting information within peroxisomal ABC transporter Pxa1. Biochimica et Biophysica Acta - Molecular Cell Research, 1870(5), Article 119471. https://doi.org/10.1016/j.bbamcr.2023.119471

Rampelt, H., Wollweber, F., Licheva, M., de Boer, R., Perschil, I., Steidle, L., Becker, T., Bohnert, M., van der Klei, I., Kraft, C., van der Laan, M., & Pfanner, N. (2022). Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth. Cell reports, 38(4), Article 110290. https://doi.org/10.1016/j.celrep.2021.110290

Wu, F., & van der Klei, I. J. (2022). Structure-function analysis of the ER-peroxisome contact site protein Pex32. Frontiers in Cell and Developmental Biology, 10, Article 957871. https://doi.org/10.3389/fcell.2022.957871

Yuan, W., Akşit, A., de Boer, R., Krikken, A. M., & van der Klei, I. J. (2022). Yeast Vps13 is Crucial for Peroxisome Expansion in Cells With Reduced Peroxisome-ER Contact Sites. Frontiers in Cell and Developmental Biology, 10, Article 842285. https://doi.org/10.3389/fcell.2022.842285

Jansen, R. L. M., Santana-Molina, C., van den Noort, M., Devos, D. P., & van der Klei, I. J. (2021). Comparative Genomics of Peroxisome Biogenesis Proteins: Making Sense of the PEX Proteins. Frontiers in Cell and Developmental Biology, 9, Article 654163. https://doi.org/10.3389/fcell.2021.654163

Zielińska, A., Savietto, A., de Sousa Borges, A., Martinez, D., Berbon, M., Roelofsen, J. R., Hartman, A. M., de Boer, R., Van der Klei, I. J., Hirsch, A. K., Habenstein, B., Bramkamp, M., & Scheffers, D.-J. (2020). Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement. eLife, 9, 1-21. Article e57179. https://doi.org/10.7554/eLife.57179

Singh, R., Wróblewska, J., de Boer, R., & van der Klei, I. J. (2020). Hansenula Polymorpha Vac8: A Vacuolar Membrane Protein Required for Vacuole Inheritance and Nucleus-Vacuole Junction Formation. Contact, 3, 1-8. https://doi.org/10.1177/2515256420974928

Krikken, A. M., Wu, H., de Boer, R., Devos, D. P., Levine, T. P., & van der Klei, I. J. (2020). Peroxisome retention involves Inp1-dependent peroxisome-plasma membrane contact sites in yeast. The Journal of Cell Biology, 219(10), Article e201906023. https://doi.org/10.1083/jcb.201906023

Wu, F., de Boer, R., Krikken, A. M., Akşit, A., Bordin, N., Devos, D. P., & van der Klei, I. J. (2020). Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast. Journal of Cell Science, 133(16), Article jcs.246983. https://doi.org/10.1242/jcs.246983

Singh, R., Manivannan, S., Krikken, A. M., de Boer, R., Bordin, N., Devos, D. P., & van der Klei, I. J. (2020). Hansenula polymorpha Pex37 is a peroxisomal membrane protein required for organelle fission and segregation. The FEBS Journal, 287(9), 1742-1757. https://doi.org/10.1111/febs.15123

Wu, H., & van der Klei, I. J. (2019). Novel Peroxisome–Vacuole Contacts in Yeast. Contact, 2, 1-3. https://doi.org/10.1177/2515256419829623

Wu, H., de Boer, R., Krikken, A. M., Akşit, A., Yuan, W., & van der Klei, I. J. (2019). Peroxisome development in yeast is associated with the formation of Pex3-dependent peroxisome-vacuole contact sites. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1866(3), 349-359. https://doi.org/10.1016/j.bbamcr.2018.08.021

Wróblewska, J. P., & van der Klei, I. J. (2019). Peroxisome Maintenance Depends on De Novo Peroxisome Formation in Yeast Mutants Defective in Peroxisome Fission and Inheritance. International Journal of Molecular Sciences, 20(16), Article 4023. https://doi.org/10.3390/ijms20164023

Costello, J. L., Zalckvar, E., Kemp, S., di Cara, F., Kim, P. K., Linka, N., & van der Klei, I. J. (2019). Peroxisomes: New insights into protein sorting, dynamics, quality control, signalling and roles in health and disease. Histochemistry and cell biology, 151(4), 283-289. https://doi.org/10.1007/s00418-019-01780-w

Jansen, R. L. M., & van der Klei, I. J. (2019). The peroxisome biogenesis factors Pex3 and Pex19: Multitasking proteins with disputed functions. FEBS Letters, 593(5), 457-474. https://doi.org/10.1002/1873-3468.13340

Rampelt, H., Wollweber, F., Gerke, C., de Boer, R., van der Klei, I. J., Bohnert, M., Pfanner, N., & van der Laan, M. (2018). Assembly of the Mitochondrial Cristae Organizer Mic10 is Regulated by Mic26-Mic27 Antagonism and Cardiolipin. Journal of Molecular Biology, 430(13), 1883-1890. https://doi.org/10.1016/j.jmb.2018.04.037

Aksit, A., & van der Klei, I. J. (2018). Yeast peroxisomes: How are they formed and how do they grow? International journal of biochemistry & cell biology, 105, 24-34. https://doi.org/10.1016/j.biocel.2018.09.019

Kumar, S., de Boer, R., & van der Klei, I. J. (2018). Yeast cells contain a heterogeneous population of peroxisomes that segregate asymmetrically during cell division. Journal of Cell Science, 131(3), Article jcs.207522. https://doi.org/10.1242/jcs.207522

Wroblewska, J. P., Cruz-Zaragoza, L. D., Yuan, W., Schummer, A., Chuartzman, S. G., de Boer, R., Oeljeklaus, S., Schuldiner, M., Zalckvar, E., Warscheid, B., Erdmann, R., & van der Klei, I. J. (2017). Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins. Biochimica et Biophysica Acta - Molecular Cell Research, 1864(10), 1656-1667. Article bbamcr.2017.05.021. https://doi.org/10.1016/j.bbamcr.2017.05.021

Kawalek, A., Jagadeesan, C., & van der Klei, I. J. (2016). Impaired biosynthesis of the non-bilayer lipids phosphatidylethanolamine or cardiolipin does not affect peroxisome biogenesis and proliferation in Saccharomyces cerevisiae. Biochemical and Biophysical Research Communications, 480(2), 228-233. https://doi.org/10.1016/j.bbrc.2016.10.033

Kumar, S., Singh, R., Williams, C. P., & van der Klei, I. J. (2016). Stress exposure results in increased peroxisomal levels of yeast Pnc1 and Gpd1, which are imported via a piggy-backing mechanism. Biochimica et Biophysica Acta-Molecular Cell Research, 1863(1), 148-156. https://doi.org/10.1016/j.bbamcr.2015.10.017

Yuan, W., Veenhuis, M., & van der Klei, I. J. (2016). The birth of yeast peroxisomes. Biochimica et biophysica acta, 1863(5), 902-910. Article 17661. https://doi.org/10.1016/j.bbamcr.2015.09.008

Bohnert, M., Zerbes, R. M., Davies, K. M., Mühleip, A. W., Rampelt, H., Horvath, S. E., Boenke, T., Kram, A., Perschil, I., Veenhuis, M., Kühlbrandt, W., van der Klei, I. J., Pfanner, N., & van der Laan, M. (2015). Central role of mic10 in the mitochondrial contact site and cristae organizing system. Cell Metabolism, 21(5), 747-755. https://doi.org/10.1016/j.cmet.2015.04.007

Lefevre, S. D., Kumar, S., & van der Klei, I. J. (2015). Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan. Cell Cycle, 14(11), 1698-1703. https://doi.org/10.1080/15384101.2015.1029685

Thomas, A. S., Krikken, A. M., van der Klei, I. J., & Williams, C. P. (2015). Phosphorylation of Pex11p does not regulate peroxisomal fission in the yeast Hansenula polymorpha. Scientific Reports, 5, 1-11. Article 11493. https://doi.org/10.1038/srep11493

Williams, C., Opalinski, L., Landgraf, C., Costello, J., Schrader, M., Krikken, A. M., Knoops, K., Kram, A. M., Volkmer, R., & van der Klei, I. J. (2015). The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission. Proceedings of the National Academy of Sciences of the United States of America, 112(20), 6377-6382. https://doi.org/10.1073/pnas.1418736112

Knoops, K., de Boer, R., Kram, A., & van der Klei, I. J. (2015). Yeast pex1 cells contain peroxisomal ghosts that import matrix proteins upon reintroduction of Pex1. The Journal of Cell Biology, 211(5), 955-962. https://doi.org/10.1083/jcb.201506059

Veenhuis, M., & van der Klei, I. J. (2014). A critical reflection on the principles of peroxisome formation in yeast. Frontiers in Physiology, 5, Article 110. https://doi.org/10.3389/fphys.2014.00110

Kawalek, A., & van der Klei, I. (2014). At neutral pH the chronological lifespan of Hansenula polymorpha increases upon enhancing the carbon source concentration. Microbial Cell, 1(6), 189-202. https://doi.org/10.15698/mic2014.06.149

Veenhuis, M., & van der Klei, I. J. (2014). De novo peroxisome biogenesis revisited. Microbial Cell, 1(4), 128-130. https://doi.org/10.15698/mic2014.04.138

Hettema, E. H., Erdmann, R., van der Klei, I., & Veenhuis, M. (2014). Evolving models for peroxisome biogenesis. Current Opinion in Cell Biology, 29C, 25-30. https://doi.org/10.1016/j.ceb.2014.02.002

van Zutphen, T., Todde, V., de Boer, R., Kreim, M., Hofbauer, H. F., Wolinski, H., Veenhuis, M., Klei, I. J. V. D., & Kohlwein, S. D. (2014). Lipid droplet autophagy in the yeast Saccharomyces cerevisiae. Molecular Biology of the Cell, 25(2), 290-301. https://doi.org/10.1091/mbc.E13-08-0448

Kumar, S., Kawalek, A., & van der Klei, I. J. (2014). Peroxisomal quality control mechanisms. Current Opinion in Microbiology, 22, 30-37. https://doi.org/10.1016/j.mib.2014.09.009

Knoops, K., Manivannan, S., Cepinska, M. N., Krikken, A. M., Kram, A. M., Veenhuis, M., & van der Klei, I. J. (2014). Preperoxisomal vesicles can form in the absence of Pex3. The Journal of Cell Biology, 204(5), 659-668. https://doi.org/10.1083/jcb.201310148

Pfanner, N., van der Laan, M., Amati, P., Capaldi, R. A., Caudy, A. A., Chacinska, A., Darshi, M., Deckers, M., Hoppins, S., Icho, T., Jakobs, S., Ji, J., Kozjak-Pavlovic, V., Meisinger, C., Odgren, P. R., Park, S. K., Rehling, P., Reichert, A. S., Sheikh, M. S., ... Nunnari, J. (2014). Uniform nomenclature for the mitochondrial contact site and cristae organizing system. The Journal of Cell Biology, 204(7), 1083-1086. https://doi.org/10.1083/jcb.201401006

Scheckhuber, C. Q., Veenhuis, M., & van der Klei, I. J. (2013). Improving penicillin biosynthesis in Penicillium chrysogenum by glyoxalase overproduction. Metabolic Engineering, 18, 36-43. https://doi.org/10.1016/j.ymben.2013.04.003

Kohlwein, S. D., Veenhuis, M., & van der Klei, I. J. (2013). Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat-Store 'em Up or Burn 'em Down. Genetics, 193(1), 1-50. https://doi.org/10.1534/genetics.112.143362

Manivannan, S., de Boer, R., Veenhuis, M., & van der Klei, I. J. (2013). Lumenal peroxisomal protein aggregates are removed by concerted fission and autophagy events. Autophagy, 9(7), 1044-1056. https://doi.org/10.4161/auto.24543

Kawalek, A., Lefevre, S. D., Veenhuis, M., & van der Klei, I. J. (2013). Peroxisomal catalase deficiency modulates yeast lifespan depending on growth conditions. Aging-Us, 5(1), 67-83. https://doi.org/10.18632/aging.100519

Williams, C., & van der Klei, I. J. (2013). Pexophagy-linked degradation of the peroxisomal membrane protein Pex3p involves the ubiquitin-proteasome system. Biochemical and Biophysical Research Communications, 438(2), 395-401. https://doi.org/10.1016/j.bbrc.2013.07.086

Lefevre, S. D., van Roermund, C. W., Wanders, R. J. A., Veenhuis, M., & van der Klei, I. J. (2013). The significance of peroxisome function in chronological aging of Saccharomyces cerevisiae. Aging Cell, 12(5), 784-793. https://doi.org/10.1111/acel.12113

Opalinski, L., Bartoszewska, M., Fekken, S., Liu, H., de Boer, R., van der Klei, I., Veenhuis, M., & Kiel, J. A. K. W. (2012). De Novo Peroxisome Biogenesis in Penicillium Chrysogenum Is Not Dependent on the Pex11 Family Members or Pex16. PLoS ONE, 7(4), Article e35490. https://doi.org/10.1371/journal.pone.0035490

Kumar, S., Lefevre, S. D., Veenhuis, M., & van der Klei, I. J. (2012). Extension of Yeast Chronological Lifespan by Methylamine. PLoS ONE, 7(11), Article e48982. https://doi.org/10.1371/journal.pone.0048982

et al., Carra, S., Kampinga, H. H., Kiel, J. A. K. W., & van der Klei, I. J. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4), 445-544. https://doi.org/10.4161/auto.19496

Veiga, T., Gombert, A. K., Landes, N., Verhoeven, M. D., Kiel, J. A. K. W., Krikken, A. M., Nijland, J. G., Touw, H., Luttik, M. A. H., van der Toorn, J. C., Driessen, A. J. M., Bovenberg, R. A. L., van den Berg, M. A., van der Klei, I. J., Pronk, J. T., & Daran, J.-M. (2012). Metabolic engineering of beta-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis. Metabolic Engineering, 14(4), 437-448. https://doi.org/10.1016/j.ymben.2012.02.004

Zerbes, R. M., van der Klei, I. J., Veenhuis, M., Pfanner, N., van der Laan, M., & Bohnert, M. (2012). Mitofilin complexes: conserved organizers of mitochondrial membrane architecture. Biological Chemistry, 393(11), 1247-1261. https://doi.org/10.1515/hsz-2012-0239

Saraya, R., Krikken, A. M., Kiel, J. A. K. W., Baerends, R. J. S., Veenhuis, M., & van der Klei, I. J. (2012). Novel genetic tools for Hansenula polymorpha. Fems Yeast Research, 12(3), 271-278. https://doi.org/10.1111/j.1567-1364.2011.00772.x

Bartoszewska, M., Williams, C., Kikhney, A., Opalinski, L., van Roermund, C. W. T., de Boer, R., Veenhuis, M., & van der Klei, I. J. (2012). Peroxisomal Proteostasis Involves a Lon Family Protein That Functions as Protease and Chaperone. The Journal of Biological Chemistry, 287(33), 27380-27395. https://doi.org/10.1074/jbc.M112.381566

Otzen, M., Rucktaeschel, R., Thoms, S., Ernmrich, K., Krikken, A. M., Erdmann, R., van der Klei, I. J., Emmrich, K., & Krikken, A. M. (2012). Pex19p Contributes to Peroxisome Inheritance in the Association of Peroxisomes to Myo2p. Traffic, 13(7), 947-959. https://doi.org/10.1111/j.1600-0854.2012.01364.x

Zerbes, R. M., Bohnert, M., Stroud, D. A., von der Malsburg, K., Kram, A., Oeljeklaus, S., Warscheid, B., Becker, T., Wiedemann, N., Veenhuis, M., van der Klei, I. J., Pfanner, N., & van der Laan, M. (2012). Role of MINOS in Mitochondrial Membrane Architecture: Cristae Morphology and Outer Membrane Interactions Differentially Depend on Mitofilin Domains. Journal of Molecular Biology, 422(2), 183-191. https://doi.org/10.1016/j.jmb.2012.05.004

Bohnert, M., Wenz, L.-S., Zerbes, R. M., Horvath, S. E., Stroud, D. A., von der Malsburg, K., Mueller, J. M., Oeljeklaus, S., Perschil, I., Warscheid, B., Chacinska, A., Veenhuis, M., van der Klei, I. J., Daum, G., Wiedemann, N., Becker, T., Pfanner, N., & van der Laan, M. (2012). Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane. Molecular Biology of the Cell, 23(20), 3948-3956. https://doi.org/10.1091/mbc.E12-04-0295

Manivannan, S., Scheckhuber, C. Q., Veenhuis, M., & van der Klei, I. J. (2012). The impact of peroxisomes on cellular aging and death. Frontiers in Oncology, 2(7), 1-7. Article 50. https://doi.org/10.3389/fonc.2012.00050

Zerbes, R. M., Bohnert, M., Malsburg, K. V. D., Warscheid, B., Klei, I. J. V. D., Pfanner, N., & Laan, M. V. D. (2012). The MINOS complex: Keeper of mitochondrial membrane architecture. Biochimica et Biophysica Acta, 1817(33), S74-S75. https://doi.org/10.1016/j.bbabio.2012.06.208

Williams, C., Aksam, E. B., Gunkel, K., Veenhuis, M., & van der Klei, I. J. (2012). The relevance of the non-canonical PTS1 of peroxisomal catalase. Biochimica et Biophysica Acta-Molecular Cell Research, 1823(7), 1133-1141. https://doi.org/10.1016/j.bbamcr.2012.04.006

Bartosweska, M., Kiel, J. A. K. W., Bovenberg, R. A. L., Veenhuis, M., & van der Klei, I. J. (2011). Autophagy Deficiency Promotes β-Lactam Production in Penicillium chrysogenum. Applied and environmental microbiology, 77(4), 1413-1422. https://doi.org/10.1128/aem.01531-10

Boender, L. G. M., van Maris, A. J. A., de Hulster, E. A. F., Almering, M. J. H., van der Klei, I. J., Veenhuis, M., de Winde, J. H., Pronk, J. T., & Daran-Lapujade, P. (2011). Cellular responses of Saccharomyces cerevisiae at near-zero growth rates: transcriptome analysis of anaerobic retentostat cultures. Fems Yeast Research, 11(8), 603-620. https://doi.org/10.1111/j.1567-1364.2011.00750.x

van Zutphen, T., Veenhuis, M., & van der Klei, I. J. (2011). Damaged peroxisomes are subject to rapid autophagic degradation in the yeast Hansenula polymorpha. Autophagy, 7(8), 863-872. https://doi.org/10.4161/auto.7.8.15697

von der Malsburg, K., Mueller, J. M., Bohnert, M., Oeljeklaus, S., Kwiatkowska, P., Becker, T., Loniewska-Lwowska, A., Wiese, S., Rao, S., Milenkovic, D., Hutu, D. P., Zerbes, R. M., Schulze-Specking, A., Meyer, H. E., Martinou, J.-C., Rospert, S., Rehling, P., Meisinger, C., Veenhuis, M., ... Müller, J. M. (2011). Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis. Developmental Cell, 21(4), 694-707. https://doi.org/10.1016/j.devcel.2011.08.026

van der Klei, I. J. (2011). Live by fusion, avoid fission: Comment on: Scheckhuber CQ, et al. Cell Cycle 2011; 10:3105–10. Cell Cycle, 10(22), 3826. https://doi.org/10.4161/cc.10.22.18234

Opalinski, L., Kiel, J. A. K. W., Williams, C., Veenhuis, M., & van der Klei, I. J. (2011). Membrane curvature during peroxisome fission requires Pex11. EMBO Journal, 30(1), 5-16. https://doi.org/10.1038/emboj.2010.299

Krygowska, M., Veenhuis, M., Klei, I. J. V. D., & Nagotu, S. (2011). Peroxisome Fission is Associated with Reorganization of Specific Membrane Proteins. Traffic, 12(7), 925-937. https://doi.org/10.1111/j.1600-0854.2011.01198.x

Opalinski, L., Veenhuis, M., & van der Klei, I. J. (2011). Peroxisomes: Membrane events accompanying peroxisome proliferation. International journal of biochemistry & cell biology, 43(6), 847-851. https://doi.org/10.1016/j.biocel.2011.03.006

van Zutphen, T., & van der Klei, I. J. (2011). Quantitative analysis of organelle abundance, morphology and dynamics. Current Opinion in Biotechnology, 22(1), 127-132. https://doi.org/10.1016/j.copbio.2010.10.015

Bartoszewska, M., Opalinski, L., Veenhuis, M., & van der Klei, I. J. (2011). The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi. Biotechnology Letters, 33(10), 1921-1931. https://doi.org/10.1007/s10529-011-0664-y

Saraya, R., Cepinska, M. N., Kiel, J. A. K. W., Veenhuis, M., van der Klei, I. J., & Cepińska, M. N. (2010). A conserved function for Inp2 in peroxisome inheritance. Biochimica et Biophysica Acta-Molecular Cell Research, 1803(5), 617 - 622. https://doi.org/10.1016/j.bbamcr.2010.02.001

Klompmaker, S. H., Kilic, A., Baerends, R. J., Veenhuis, M., & van der Klei, I. J. (2010). Activation of a peroxisomal Pichia pastoris d-amino acid oxidase, which uses d-alanine as a preferred substrate, depends on pyruvate carboxylase. Fems Yeast Research, 10(6), 708-716. https://doi.org/10.1111/j.1567-1364.2010.00647.x

van Zutphen, T., Baerends, R. J. S., Susanna, K., de Jong, A., Kuipers, O. P., Veenhuis, M., & van der Klei, I. J. (2010). Adaptation of Hansenula polymorpha to methanol: A transcriptome analysis. BMC Genomics, 11(1). https://doi.org/10.1186/1471-2164-11-1

van den Berg, M. A., Gidijala, L., Kiel, J. A. K. W., Bovenberg, R. A. L., & van der Klei, I. J. (2010). Biosynthesis of active pharmaceuticals: β-lactam biosynthesis in filamentous fungi. Biotechnol Genet Eng Rev, 27(1), 1-31.

Nagotu, S., Veenhuis, M., & van der Klei, I. J. (2010). Divide et impera: The dictum of peroxisomes. Traffic, 11(2), 175-184. https://doi.org/10.1111/j.1600-0854.2009.01019.x

Huberts, D., & van der Klei, I. J. (2010). Moonlighting proteins: An intriguing mode of multitasking. Biochimica et Biophysica Acta-Molecular Cell Research, 1803(4), 520-525. https://doi.org/10.1016/j.bbamcr.2010.01.022

Opalinski, L., Kiel, J. A. K. W., Homan, T. G., Veenhuis, M., van der Klei, I. J., & Opaliński, Ł. (2010). Penicillium chrysogenum Pex14/17p – a novel component of the peroxisomal membrane that is important for penicillin production. Febs Journal, 277(15), 3203-3218. https://doi.org/10.1111/j.1742-4658.2010.07726.x

Meijer, W. H., Gidijala, L., Fekken, S., Kiel, J. A. K. W., van den Berg, M. A., Lascaris, R., Bovenberg, R. A. L., & van der Klei, I. J. (2010). Peroxisomes are required for efficient penicillin biosynthesis in Penicillium chrysogenum. Applied and environmental microbiology, 76(17), 5702-5709. https://doi.org/10.1128/AEM.02327-09

Saraya, R., Veenhuis, M., & van der Klei, I. J. (2010). Peroxisomes as dynamic organelles: peroxisome abundance in yeast. Febs Journal, 277(16), 3279-3288. https://doi.org/10.1111/j.1742-4658.2010.07740.x

van der Klei, I. J. (2010). Peroxisomes as dynamic organelles. Febs Journal, 277(16), 3267. https://doi.org/10.1111/j.1742-4658.2010.07738.x

Huberts, D. H. E. W., Venselaar, H., Vriend, G., Veenhuis, M., & van der Klei, I. J. (2010). The moonlighting function of pyruvate carboxylase resides in the non-catalytic end of the TIM barrel. Biochimica et Biophysica Acta-Molecular Cell Research, 1803(9), 1038-1042. https://doi.org/10.1016/j.bbamcr.2010.03.018

Koetsier, M. J., Gombert, A. K., Fekken, S., Bovenberg, R. A. L., Van den Berg, M. A., Kiel, J. A. K. W., Jekel, P. A., Janssen, D. B., Pronk, J. T., Van der Klei, I. J., & Daran, J.-M. (2010). The Penicillium chrysogenum aclA gene encodes a broad-substrate-specificity acyl-coenzyme A ligase involved in activation of adipic acid, a side-chain precursor for cephem antibiotics. Fungal Genetics and Biology, 47(1), 33-42. https://doi.org/10.1016/j.fgb.2009.10.003

Gidijala, L., Kiel, J. A. K. W., Douma, R. D., Seifar, R. M., van Gulik, W. M., Bovenberg, R. A. L., Veenhuis, M., & van der Klei, I. J. (2009). An Engineered Yeast Efficiently Secreting Penicillin. PLoS ONE, 4(12), Article 8317. https://doi.org/10.1371/journal.pone.0008317

Todde, V., Veenhuis, M., & van der Klei, I. J. (2009). Autophagy: Principles and significance in health and disease. Biochimica et biophysica acta-Molecular basis of disease, 1792(1), 3-13. https://doi.org/10.1016/j.bbadis.2008.10.016

Krikken, A. M., Veenhuis, M., & van der Klei, I. J. (2009). Hansenula polymorpha pex11 cells are affected in peroxisome retention. Febs Journal, 276(5), 1429-1439. https://doi.org/10.1111/j.1742-4658.2009.06883.x

Kiel, J. A. K. W., van den Berg, M. A., Fusetti, F., Poolman, B., Bovenberg, R. A. L., Veenhuis, M., & van der Klei, I. J. (2009). Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells. FUNCTIONAL & INTEGRATIVE GENOMICS, 9(2), 167-184. https://doi.org/10.1007/s10142-009-0110-6

Kurbatova, E., Otzen, M., & van der Klei, I. J. (2009). p24 proteins play a role in peroxisome proliferation in yeast. FEBS Letters, 583(19), 3175-3180. https://doi.org/10.1016/j.febslet.2009.08.040

Sagt, C. M. J., Haaft, P. J. T., Minneboo, I. M., Hartog, M. P., Damveld, R. A., Laan, J. M. V. D., Akeroyd, M., Wenzel, T. J., Luesken, F. A., Veenhuis, M., Klei, I. V. D., & Winde, J. H. D. (2009). Peroxicretion: a novel secretion pathway in the eukaryotic cell. BMC Biotechnology, 9(1), Article 48. https://doi.org/10.1186/1472-6750-9-48

Aksam, E. B., de Vries, B., van der Klei, I. J., & Kiel, J. A. K. W. (2009). Preserving organelle vitality: peroxisomal quality control mechanisms in yeast. Fems Yeast Research, 9(6), 808-820. https://doi.org/10.1111/j.1567-1364.2009.00534.x

Kiel, J. A. K. W., & van der Klei, I. J. (2009). Proteins involved in microbody biogenesis and degradation in Aspergillus nidulans. Fungal Genetics and Biology, 46(1), S62-S71. https://doi.org/10.1016/j.fgb.2008.07.009