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Research ENTEG Bioproduct Engineering

Bioproduct Engineering (van der Maarel)

The research done in the Bioproduct Engineering (BE) unit focuses on the biocatalysis of carbohydrates, in particular on enzymes acting on starch/glycogen and hemicellulose/xylan. The more fundamental research is directed to understanding enzyme structure and properties, studying natural diversity of enzymes, and getting insights into the changes of the carbohydrate structure and physical properties upon the enzyme’s action. Examples are 1) the biosynthesis and structure of NanoGlycogen from the red microalgae Galdieria sulphuraria, the structure-function relationship of GH13 and GH57 microbial glycogen branching enzymes. 2) unravelling the function of uncharacterized enzymes from xylan related GH families and enzymes of unknown function (UNKs) from bacterial gene clusters trough transcriptomic and sequence analysis and in-depth biochemical characterization.

Secretary Yvonne Numan
Telephone

+31 50 363 7396

Postal address University of Groningen
Nijenborgh 4
NL-9747 AG Groningen
The Netherlands
Chair Prof. Dr. M. J. E. C. van der Maarel

Scientific staff

Prof. dr. Marc J.E.C. van der Maarel
Prof. dr. Marc J.E.C. van der Maarel

Full Professor

Name Research Expertise

Prof. dr. Marc J.E.C. van der Maarel

Professor van der Maarel focuses on enzymatic and highly branched α-glucans

Biotechnology & Applied Microbiology, Microbiology, Food Science & Technology, Intellectual Property and Patents , Applied Biocatalysis, Starch, Carbohydrates

Dr. Edita Jurak
Dr. Edita Jurak

Assistent Professor

Name Research Expertise
dr. Edita Jurak

Edita’s research focuses on discovery and characterization of carbohydrate active enzymes (CAZymes) and plant biomass carbohydrate chemistry

Carbohydrate analytical chemistry, protein sequence analysis, purification and enzyme characterization

PhD Students

Lisanne Hameleers
Lisanne Hameleers
Jason Xiang
Jason Xiang
Hilda Bax
Hilda Bax
Salvador Bertran Llorens
Salvador Bertran Llorens
Ima Kristijarti
Ima Kristijarti

Name Research
Lisanne Hameleers

'Exploiting PULs for the discovery of Carbohydrate Active enZymes (CAZymes)'

Investigating clusters of related genes (Polysaccharide Utilization Loci, PULs) from bacterial sources for the discovery of novel CAZymes with putative applications for the conversion of biowaste into bio-based products. This will be achieved through semi-throughput screening system, followed by in-depth biochemical enzyme characterization on natural substrates.

Jason Xiang

"In-depth investigation of glycogen branching enzymes (GBE) from glycoside hydrolase (GH) family 57 from bioinformatic and biochemical aspect"

Hilda Bax

Research on characterizing glycogen branching enzymes and understanding of their mode of action, as well as their influence on glycan structures and properties

Salvador Bertran Llorens

Discovery of new CAZymes from aquatic decaying lignocellulosic biomass

Unravelling the enzyme active on recalcitrant polysaccharides and lignin by aquatic bacterial enrichment of these fractions through transcriptome analysis of CAZyme Genetic Clusters (CGC) and Polysaccharide Utilization Loci (PULs)

Ima Kristijarti

‘Structure and application of NanoGlycogens derived from various Galdieria strains’

Investigation of highly branched glycogens isolated from various Galdieria strains and application potential of benzylated/octanylated Galdieria glycogens

Support Staff

Alle van Wijk
Alle van Wijk
Jan Haas
Jan Haas

Name Position
Alle van Wijk Senior analist
Jan Haas Lab technician
Last modified:23 March 2021 09.43 a.m.