Bioproduct Engineering (van der Maarel)
The research done in the Bioproduct Engineering (BE) unit focuses on the biocatalysis of carbohydrates, in particular on enzymes acting on starch/glycogen and hemicellulose/xylan. The more fundamental research is directed to understanding enzyme structure and properties, studying natural diversity of enzymes, and getting insights into the changes of the carbohydrate structure and physical properties upon the enzyme’s action. Examples are 1) the biosynthesis and structure of NanoGlycogen from the red microalgae Galdieria sulphuraria, the structure-function relationship of GH13 and GH57 microbial glycogen branching enzymes. 2) unravelling the function of uncharacterized enzymes from xylan related GH families and enzymes of unknown function (UNKs) from bacterial gene clusters trough transcriptomic and sequence analysis and in-depth biochemical characterization.
+31 50 363 7396
|Postal address||University of Groningen
NL-9747 AG Groningen
|Chair||Prof. Dr. M. J. E. C. van der Maarel|
|Professor van der Maarel focuses on enzymatic and highly branched α-glucans||
Biotechnology & Applied Microbiology, Microbiology, Food Science & Technology, Intellectual Property and Patents , Applied Biocatalysis, Starch, Carbohydrates
|dr. Edita Jurak||
Edita’s research focuses on discovery and characterization of carbohydrate active enzymes (CAZymes) and plant biomass carbohydrate chemistry
Carbohydrate analytical chemistry, protein sequence analysis, purification and enzyme characterization
'Exploiting PULs for the discovery of Carbohydrate Active enZymes (CAZymes)'
Investigating clusters of related genes (Polysaccharide Utilization Loci, PULs) from bacterial sources for the discovery of novel CAZymes with putative applications for the conversion of biowaste into bio-based products. This will be achieved through semi-throughput screening system, followed by in-depth biochemical enzyme characterization on natural substrates.
"In-depth investigation of glycogen branching enzymes (GBE) from glycoside hydrolase (GH) family 57 from bioinformatic and biochemical aspect"
Research on characterizing glycogen branching enzymes and understanding of their mode of action, as well as their influence on glycan structures and properties
Understanding the specificity and activity of a selected number of glycogen branching enzymes (GBE) from glycoside hydrolase (GH) family 13_8 from both prokaryotic and eukaryotic microorganisms.
|Salvador Bertran Llorens||
Discovery of new CAZymes from aquatic decaying lignocellulosic biomass
Unravelling the enzyme active on recalcitrant polysaccharides and lignin by aquatic bacterial enrichment of these fractions through transcriptome analysis of CAZyme Genetic Clusters (CGC) and Polysaccharide Utilization Loci (PULs)
‘Structure and application of NanoGlycogens derived from various Galdieria strains’
Investigation of highly branched glycogens isolated from various Galdieria strains and application potential of benzylated/octanylated Galdieria glycogens
|Alle van Wijk||Senior analist|
|Jan Haas||Lab technician|
|Last modified:||22 December 2021 4.39 p.m.|