BCN Lectures

Join the upcoming BCN lectures!

BCN Lecture July - Join in person or online!

July, 2025: BCN Lecture: Sinan Guloksuz (Associate Professor of Psychiatry at Maastricht University and Specialized Treatment Early in Psychosis (STEP) Program, Yale University School of Medicine)
Title: “Exposome meets genome in shaping mental health trajectories”
Time: 12:00 – 13:00, July 3, 2025
EC: 0.2 EC for PhD students, to be added to Hora Finita by yourself
Location: Anda Kerkhoven Center, Antonius Deusinglaan 1, Room 3227.0133
Online: https://meet.google.com/zqk-tpjj-ubw
Next BCN Lecture: September 4. Time 12:00 hrs. by Roelant Ossewaarde

“Exposome meets genome in shaping mental health trajectories”

There is active interest in understanding the relationship between neuropsychiatric disorders and modifiable and potentially preventable environmental exposures. However, the complexity of the environment, involving many causal and noncausal pathways, continues to make research challenging.  In this presentation, I will begin by introducing the exposome paradigm and discuss how it can help address this complexity, facilitating a more integrated approach to environmental and genetic research. I will also demonstrate how a cumulative environmental score, exposome score for schizophrenia, can be used for risk stratification, outcome forecasting, and enhancing clinical characterization. Subsequently, I will report agnostic exposome-wide analyses that might be the first step to mapping the exposome of mental health phenotypes. Finally, I will go beyond the state of the art by introducing the ongoing work of our group within the projects YouthGEMs, HAMLETT-OPHELIA, and MINDSET.

Dr. Sinan Guloksuz, MD, MSc, PhD is Associate Professor of Psychiatry at Maastricht University and Yale School of Medicine (STEP Program). Trained in psychiatry and epidemiology, his research focuses on the interplay between genes and environment in psychosis, particularly early detection and prevention. He introduced the exposome paradigm in psychiatry and developed the exposome score for schizophrenia, a novel tool to quantify cumulative environmental risk. His work has advanced our understanding of gene-environment interactions and improved psychosis risk prediction. Dr. Guloksuz has authored over 200 peer-reviewed publications and received awards from leading psychiatric organizations. He currently leads research within major EU and national projects, including Youth-GEMs and OPHELIA, aiming to transform psychiatric prevention through integrative genomic and exposomic approaches (https://guloksuz.com).

BCN Lecture September - More information will follow!

September 4, 2025: BCN Lecture: Roelant Ossewaarde