Skip to ContentSkip to Navigation
About us Latest news News News articles

‘Big data’ revolution gives new insight into how diseases develop

New paper in Nature Genetics
09 September 2013

Systematic identification of trans eQTLs as putative drivers of known disease associations

Harm-Jan Westra, ... Alexandra Zhernakova, Daria V Zhernakova, ... Juha Karjalainen, Sebo Withoff, ... Yang Li, Ritsert C Jansen, ... Lude Franke
Dept of Genetics, UMCG, Groningen

Published in Nature Genetics online: 08 September 2013 | doi:10.1038/ng.2756

Lude Franke and colleagues report the results of a large expression QTL study performed on peripheral blood samples from 5,311 individuals. They identify trans-eQTL effects for 103 independent loci that were previously associated with complex traits at genome-wide significance, suggesting that this approach can provide insights into the downstream effects of many trait-associated variants.

Link to full text of paper

See also www.systemsgenetics.nl

Last modified:28 October 2016 11.47 p.m.
View this page in: Nederlands

More news

  • 16 April 2024

    UG signs Barcelona Declaration on Open Research Information

    In a significant stride toward advancing responsible research assessment and open science, the University of Groningen has officially signed the Barcelona Declaration on Open Research Information.

  • 02 April 2024

    Flying on wood dust

    Every two weeks, UG Makers puts the spotlight on a researcher who has created something tangible, ranging from homemade measuring equipment for academic research to small or larger products that can change our daily lives. That is how UG...

  • 18 March 2024

    VentureLab North helps researchers to develop succesful startups

    It has happened to many researchers. While working, you suddenly ask yourself: would this not be incredibly useful for people outside of my own research discipline? There are many ways to share the results of your research. For example, think of a...