Shared genetic background of inflammatory diseases of the bowel
PhD ceremony: Ms. E.A.M. Festen, 16.15 uur, Academiegebouw, Broerstraat 5, Groningen
Title: Shared genetic background of inflammatory diseases of the bowel
Promotor(s): prof. C. Wijmenga, prof. J.H. Kleibeuker
Faculty: Medical Sciences
Crohn’s disease, ulcerative colitis, and celiac disease are chronic inflammatory bowel diseases with a relatively high prevalence in Western countries. Patients are usually bound to strict diets and/or anti-inflammatory drugs. This thesis describes research into the genetic factors involved in Crohn’s disease, ulcerative colitis and celiac disease. A screen for variants in genes in the innate immune system was used to identify new risk genes for Crohn’s disease and ulcerative colitis. It was also found that there is overlap in genetic risk between these diseases and celiac disease. The findings are relevant for our better understanding of the pathogenesis of inflammatory bowel diseases and to further research in therapeutic treatments.
Last modified: | 13 March 2020 01.09 a.m. |
More news
-
29 November 2023
UMCG opent nieuwe faciliteit voor microbioomonderzoek 
Vandaag opent het UMCG de Groningen Microbioom Hub: een nieuwe faciliteit met state-of-the-art technologie waarin alle UMCG-expertise op het gebied van microbioomonderzoek samenkomt. Dit zorgt voor unieke mogelijkheden in onderzoek en maakt nieuwe...
-
28 November 2023
Science: more exciting than showbiz
Science often seems very complicated. Most people probably don't really know what researchers do, and what it takes to make a breakthrough. That is why it is important to keep the general public informed of what is happening in science, says Iris...
-
13 November 2023
UMCG beantwoordt vragen patiënten met hulp van AI
Het UMCG zet kunstmatige intelligentie (artificial intelligence, afgekort AI) in om zorgverleners te helpen bij het beantwoorden van schriftelijke vragen van patiënten. Dit gebeurt in samenwerking met andere ziekenhuizen vanuit de EPIC Nederlandse...