Cellular aging in cardiovascular diseases

PhD ceremony: Mr. H. Oeseburg, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen

Thesis: Cellular aging in cardiovascular diseases

Promotor(s): prof. W.H. van Gilst

Faculty: Medical Sciences

In our research we focused on the presence and development of cellular senescence in cardiovascular diseases. The role of the telomeres and the enzyme telomerase during aging, and in cardiovascular diseases is discussed. In a model for telomere shortening we describe that telomere length is associated with a striking decrease in voluntary exercise, but this was not directly associated with a cardiovascular phenotype.