Role of genetic and environmental factors in tic disorders

PhD ceremony: Ms. N.G.P. Bos-Veneman, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen

Thesis: Role of genetic and environmental factors in tic disorders

Promotor(s): prof. R.B. Minderaa, prof. C.G.M. Kallenberg

Faculty: Medical Sciences

The aim of this thesis was to study associations between genetic and environmental factors and severity of tics and comorbid symptoms in patients with a tic disorder.This thesis has demonstrated associations between tics and perinatal adversities, serotonergic and dopaminergic genes, and immunological factors. Future studies that replicate our results and clarify underlying mechanisms are warranted.