PhD ceremony: dhr. J.R.N. van der Voort van Zyp, 11.00 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Colon cancer cell adhesion depends on the extracellular environment and pressure induced intracellular signaling
Promotor(s): prof.dr. H.J. Hoekstra, prof.dr. M.D. Basson
Faculty: Medical Sciences
Contact: UMCG spokesperson, tel. +3150-361 2200, e-mail:
Surgical procedures for colon cancer often cause spillage of tumor cells into the peritoneal cavity or into the circulation. When tumor cells are shed into the circulation or peritoneal cavity they are subjected to increased pressure conditions. Under these conditions a signaling cascade within the cell is activated. This can promote cell adhesion and eventual metastasis. Until recently it was unclear which processes occurred within the spilled tumor cell before adhesion. In this thesis tumor cells are exposed to specific intracellular signaling inhibitors under increased pressure conditions. Through inhibition of these signals it is possible to reduce tumor cell adhesion. This may prevent metastasis in the future.
Prof. Moniek Tromp has been appointed Captain of Science of the Chemistry Top Sector by the Minister of Economic Affairs and Climate Policy. As from 1 July 2023, she succeeded Prof. Bert Weckhuysen from Utrecht University.
Leonardo Arriagada Beltran conducted his PhD research on the interface of computer-generated art and the constantly evolving field of Artificial Intelligence (AI). He will defend his Phd thesis on 21 September. His research offers valuable insights...
Harish Vedantham and Casper van der Kooi have been nominated by New Scientist for Wetenschapstalent 2023 (Science Talent 2023). This election is meant to give young scientists and their research a stage.
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