PhD Defence Lianne ten Have

We are pleased to announce that Lianne ten Have will defend her PhD thesis 'Patient-generated real-world data in severe asthma' on 4 June 2026 in the Auditorium of Campus Fryslân, Wirdumerdijk 34, 8911 CE Leeuwarden.

It is possible to follow the defence online via the livestream.

Programme:

• 13:30 - Layperson’s talk

• 14:00 - PhD defence

About the thesis

In this dissertation, Lianne ten Have examined outcomes that are important to people with severe asthma, such as fatigue, physical activity, quality of life. Across several studies, Lianne investigated how these outcomes changed following treatments for severe asthma. In two studies, Lianne evaluated fatigue, quality of life, work productivity, activity and weight in people starting medication (biologics), and how these outcomes developed after one or two years. In two other studies, Lianne focused on fatigue and physical activity in relation to pulmonary rehabilitation at altitude. 

Although treatment with medication (biologics) and pulmonary rehabilitation programs lead to meaningful improvements for many, a substantial proportion of patients continue to experience a high disease burden. These findings highlight that patient-centred care in severe asthma goes beyond symptom control and lung function. It requires sustained attention to lived disease burden, comorbidities, and broader outcomes such as sleep, weight, and work. Only by adopting this broader approach can care truly align with the goals and needs of people living with severe asthma.

You can read Lianne's entire thesis here.