T. (Tiago) Medeiros Furquim Mendonça, MSc

Lecturer of Health and Life Sciences, and Neuroscience (UCG), PhD candidate (UMCG)He/Him

University College Groningen

Telephone:

Faculty of Medical Sciences

Telephone:

E-mail:

t.medeiros.furquim rug.nl

Homepage ORCID Research Portal

Research interests

Microglia biology, immunology and neuroscience.

Publications

Microglia endotoxin tolerance is retained after enforced repopulation

Medeiros-Furquim, T., Miedema, A., Schilder, E., Brouwer, N., Holtman, I. R., Kooistra, S. M. & Eggen, B. J. L., Aug-2025, In: Brain, Behavior, and Immunity. 128, p. 512-528 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

Pharmacological microglia depletion followed by repopulation ameliorates recurrent cuprizone-induced demyelination

Medeiros-Furquim, T., Miedema, A., Hukema, F., Schilder, E., Eggens-Meijer, E., Kooistra, S. & Eggen, B., 2022, In: Multiple sclerosis journal. 28, S3, P535.

Research output: Contribution to journal › Meeting Abstract › Academic

Vascular Basement Membranes Establish a β2-Integrin-Dependent Macrophage-Preadipocyte Niche that Guides Adipose Tissue Fate

Correa, L. H., Medeiros-Furquim, T., Deshpande, T., Schnell, L., Wachten, D., Shi, Y., Wang, Y. & Sorokin, L., 4-Aug-2026, (Submitted) Research Square Company.

Research output: Working paper › Preprint › Academic

Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation

Medeiros-Furquim, T., Ayoub, S., Johnson, L. J., Aprico, A., Nwoke, E., Binder, M. D. & Kilpatrick, T. J., 6-Jun-2022, In: Frontiers in Immunology. 13, 16 p., 678817.

Research output: Contribution to journal › Article › Academic › peer-review

VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology

Borggrewe, M., Kooistra, S. M., Wesseling, E. M., Gierschek, F. L., Brummer, M. L., Nowak, E. C., Medeiros-furquim, T., Otto, T. A., Lee, S. W., Noelle, R. J., Eggen, B. J. L. & Laman, J. D., 18-May-2021, In: Acta Neuropathologica Communications. 9, 1, p. 91-109 18 p., 91.

Research output: Contribution to journal › Article › Academic › peer-review

Caspase-1/11 deficiency and cold exposure enhance the anti-tumor activity of brown adipose tissue secretome against breast cancer cells

Corrêa, L. H., Braz-de-Melo, H. A., Santos, I. D. O., Bezerra, S. P., Manchine, J. P., Lago, N. C. S., Portacio-Santos, C. M. A., Almeida, R. D. N., Ribeiro, D. J. S., Medeiros-Furquim, T., Sant’ana, L. P., de Fragas, M. G., Lopes, F. T., Guerra, R. O., Câmara, N. O. S. O., Castro, M. S., Fontes, W., Zamboni, D. S. & Magalhães, K. G., 11-Feb-2026, In: Cancer & Metabolism. 14, 1, 3.

Research output: Contribution to journal › Article › Academic › peer-review

Increased 15-hete in multiple sclerosis lesions and the resolution-promoting effect on ipsc-derived human microglia

van der Burgt, R. T. M., Alsema, A. M., Toth, G., Hansen, C. E., Medeiros-Furquim, T., Chornyi, S., van der Pol, S. M., van Elk, T. G., de Vries, H. E., Lanekoff, I., Kooistra, S. M., Giera, M. & Kooij, G., Jun-2025, p. E1165-E1166.

Research output: Contribution to conference › Abstract › Academic

Enforced microglia repopulation by CSF1R inhibition alters the microglia response to peripheral LPS but does not revert endotoxin tolerance

Medeiros-Furquim, T., Miedema, A., Schilder, E., Kooistra, S. M. & Eggen, B. J. L., 2023, In: Glia. 71, S1, T16-013A.

Research output: Contribution to journal › Meeting Abstract › Academic

Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathways

Marmolejo-Garza, A., Medeiros-Furquim, T., Rao, R., Eggen, B. J. L., Boddeke, E. & Dolga, A. M., Oct-2022, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1869, 10, 119326.

Research output: Contribution to journal › Review article › peer-review