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About us Practical matters How to find us dr. O.W. Akkerman
University Medical Center Groningen

dr. O.W. Akkerman

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E-mail:
o.w.akkerman umcg.nl
Research interests Publications Press/media

Research interests

Pharmacokinetics and pharmacodynamics of anti TB drugs

Inhalation of antimicrobial drugs

Holistic approach of TB care

Publications

Aspergillus After Lung Transplantation: Prophylaxis, Risk Factors, and the Impact on Chronic Lung Allograft Dysfunction

van Gemert, J. P., Fleurke, G. J., Akkerman, O. W., Gan, C. T., Steenhuis, W. N., Kerstjens, H. A. M., Verschuuren, E. A. M. & Postma, D. F., 18-Mar-2025, (E-pub ahead of print) In: Transplant Infectious Disease. e70020.

Research output: Contribution to journal › Article › Academic › peer-review

Azithromycin as host-directed therapy for pulmonary tuberculosis - a randomized pilot trial

Dekkers, B. G. J., Kerstjens, H. A. M., Breisnes, H. W., Leeming, D. J., Anthony, R. M., Frijlink, H. W., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C. & Akkerman, O. W., 11-Feb-2025, (E-pub ahead of print) In: The Journal of Infectious Diseases.

Research output: Contribution to journal › Article › Academic › peer-review

Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis

endTB Study Group, Garcia-Prats, A. J., Garcia-Cremades, M., Cox, V., Kredo, T., Dunbar, R., Schaaf, H. S., Seddon, J. A., Furin, J., Achar, J., Radke, K., Sachs, T., Abubakirov, A., Ahmed, S., Akkerman, O. W., Al Ani, N. A., Amanullah, F., Ahmad, N., Anderson, L. F. & Asfaw, M.& 32 others, Bango, F., Bauer, T., Becerra, M., Boeree, M., Brinkmann, F., Brown, R., Brust, J., Campbell, J. R., Carvalho, A. C., Carvalho, I., Cegielski, J. P., Centis, R., Chan, E. D., Chauhan, S., Chiang, S. S., Chan, P.-C., D'Ambrosio, L., Dalcolmo, M., Daneilyan, N., de Vries, G., Draper, H. R., Fairlie, L., Francis, J. R., Franke, M., Gegia, M., Restrepo, C. G., Guenther, A., Gureva, T., Haecker, B., Harausz, E., van der Werf, T. & Hesseling, A. C., Feb-2025, In: Lancet child & adolescent health. 9, 2, p. 100-111 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

ERS Congress 2024: highlights from the Respiratory Infections Assembly

Jonckheere, L., Papadopoulou, E., Piedepalumbo, F., Akkerman, O. W., Duarte, R. & Premuda, C., Mar-2025, In: ERJ Open Research. 11, 2, 4 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

Evaluation of Elexacafor/Tezacaftor/Ivacaftor therapy after lung transplantation in Cystic Fibrosis: The Dutch National KOALA study

KOALA study group, van Gemert, A., Luijk, B., Hellemons, M. E., Visser, K. A., Hansen, C., van der Meer, R., Gan, C. T., van der Vaart, H., Akkerman, O., Steenhuis, W. N., Verkleij, M., Heijerman, H. G. M. & Verschuuren, E., Feb-2025, In: JHLT Open. 7, 9 p., 100210.

Research output: Contribution to journal › Article › Academic › peer-review

Fluoroquinolones and rifampin combination in the backdrop of heteroresistant tuberculosis

Vogensen, V. B., Singh, S., Allende, C. J., Engelthaler, D. M., Boorgula, G. D., Thomas, T. A., Sturkenboom, M. G. G., Akkerman, O. W., Gumbo, T. & Srivastava, S., 16-Jan-2025, (E-pub ahead of print) In: Antimicrobial Agents and Chemotherapy. 69, 2, 10 p., e0108424.

Research output: Contribution to journal › Article › Academic › peer-review

Pharmacokinetics of Ivacaftor, Tezacaftor, Elexacaftor, and Lumacaftor in Special Cystic Fibrosis Populations: A Systematic Review

Elzinga, F. A., Malik, P. R. V., Akkerman, O. W., Rottier, B. L., van der Vaart, H., Touw, D. J., Koppelman, G. H. & Mian, P., 21-May-2025, (E-pub ahead of print) In: Clinical Pharmacokinetics. 48 p.

Research output: Contribution to journal › Article › Academic › peer-review

Quantification of Ivacaftor, Tezacaftor, Elexacaftor, and Lumacaftor and their active metabolites in plasma using UHPLC-MS/MS: Doors open to the application of therapeutic drug monitoring in cystic fibrosis treatment

Wessels, A. M. A., Elzinga, F. A., Koppelman, G. H., Akkerman, O. W., Mian, P. & Touw, D. J., 15-May-2025, In: Journal of Chromatography B. 1258, 8 p., 124604.

Research output: Contribution to journal › Article › Academic › peer-review

Tolerability and Pharmacokinetic Evaluation of Inhaled Dry Powder Tobramycin in Children with Cystic Fibrosis

Akkerman-Nijland, A. M., Hagedoorn, P., Rottier, B. L., Grasmeijer, F., Frijlink, H. E. W., van Luin, M., Ter Weijden, E., Merkus, P. J., Touw, D. J., Akkerman, O. W. & Koppelman, G. H., 7-Mar-2025, In: Pharmaceutics. 17, 3, 14 p., 347.

Research output: Contribution to journal › Article › Academic › peer-review

Use of putative hepatoprotective agents as an adjunct to anti-TB treatment in Europe

Kirakosyan, O., Reimann, M., Andersen, A. B., Bjarnason, A., Bakos, Á., Dyrhol-Riise, A. M., McLaughlin, A. M., Nita, C., Pieridou, D., Chesov, D., Davidavičienė, E. V., Günther, G., Atshemyan, H., Muylle, I., Solovic, I., Bruchfeld, J., Manika, K., Kuksa, L., Codecasa, L. R. & Stosic, M.& 18 others, Skowroński, M., Makek, M. J., Fréchet Jachym, M., Knappik, M., Santin, M., Yatskevich, N., Konstantynovska, O., Akkerman, O., Svetina, P., Viiklepp, P., Duarte, R., Zeynel, S., Togonidze, T., Vasankari, T., Parris, V., Özkara, Ş., Lange, C. & Brehm, T. T., Feb-2025, In: IJTLD open. 2, 2, p. 101-106 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Press/media

Margaretha (31) had tuberculose, maar geen arts die dat voor mogelijk hield

Akkerman, O.

14/05/2025

Press/Media: Expert Comment › Popular

Geen bloedtest, maar zweettest bij onderzoek naar inname tbc-medicatie

Akkerman, O.

25/03/2025

Press/Media: Expert Comment › Popular

Using Fingerprints to Detect Antibiotics

Akkerman, O.

27/12/2024

Press/Media: Expert Comment › Popular

My congress 2024 video: Respiratory infections highlights

Akkerman, O.

10/09/2024

Press/Media: Public Engagement Activities › Popular

Aletta Talks. “Air pollution: out and inside”

Akkerman, O.

08/07/2024

Press/Media: Research › Popular

Using a fingerprint for non-invasive drug monitoring

Akkerman, O.

05/07/2024

Press/Media: Expert Comment › Popular

Fingerprints shall predict regularity of TB patients on antitubercular drugs in future, says study

Akkerman, O.

05/07/2024

Press/Media: Expert Comment › Popular

Scientists can now detect antibiotics in finger sweat

Akkerman, O.

30/06/2024

Press/Media: Expert Comment › Popular

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