ing. L.A. Brouwer

Faculty of Medical Sciences

Telephone:

+31 50 361 8043

E-mail:

l.a.brouwer umcg.nl

Research Portal

Publications

Piezo1 regulates remodeling of skin-derived extracellular matrix by embedded umbilical cord mesenchymal stem cells in a stiffness-dependent fashion

Zhao, F., Zhang, X., Borghuis, T., Brouwer, L. A., Burgess, J. K., Sharma, P. K. & Harmsen, M. C., Apr-2026, In: Materials Today Bio. 37, 15 p., 102883.

Research output: Contribution to journal › Article › Academic › peer-review

Stiffness-induced destabilization of adherens junctions inhibits vascular network formation by pulmonary endothelial cells in lung-derived extracellular matrix hydrogels

Zhang, M., Brouwer, L. A., Burgess, J. K. & Harmsen, M. C., 13-Mar-2026, (E-pub ahead of print) In: Biomaterials. 331, p. 124136

Research output: Contribution to journal › Article › Academic › peer-review

H3K27Me3 abundance is associated with a decreased barrier function of endothelial cells by directly silencing VE-cadherin expression

Fledderus, J., Vanchin, B., Brouwer, L., Kuiper, T., Jongman, R. M., van Meurs, M., Harmsen, M. C. & Krenning, G., Jul-2025, In: Atherosclerosis. 406, 10 p., 119242.

Research output: Contribution to journal › Article › Academic › peer-review

Collagen-rich liver-derived extracellular matrix hydrogels augment survival and function of primary rat liver sinusoidal endothelial cells and hepatocytes

Wang, J., Zhao, F., Brouwer, L. A., Buist-Homan, M., Wolters, J. C., Moshage, H. & Harmsen, M. C., Oct-2024, In: International Journal of Biological Macromolecules. 278, 16 p., 134717.

Research output: Contribution to journal › Article › Academic › peer-review

Fibroblast alignment and matrix remodeling induced by a stiffness gradient in a skin-derived extracellular matrix hydrogel

Zhao, F., Zhang, M., Nizamoglu, M., Kaper, H., Brouwer, L. A., Borghuis, T., Burgess, J. K., Harmsen, M. C. & Sharma, P. K., 1-Jul-2024, In: Acta Biomaterialia. 182, p. 67-80 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

H3K27Me3 abundance increases fibrogenesis during endothelial-to-mesenchymal transition via the silencing of microRNA-29c

Fledderus, J., Brouwer, L., Kuiper, T., Harmsen, M. C. & Krenning, G., 7-May-2024, In: Frontiers in cardiovascular medicine. 11, 15 p., 1373279.

Research output: Contribution to journal › Article › Academic › peer-review

Liver-derived extracellular matrix hydrogels augment the survival and function of primary rat liver sinusoidal endothelial cells

Wang, J., Zhao, F., Brouwer, L., Buist-Homan, M., Moshage, H. J. & Harmsen, M., 15-Oct-2024, In: Hepatology.

Research output: Contribution to journal › Meeting Abstract › Academic

Physical Properties and Biochemical Composition of Extracellular Matrix-Derived Hydrogels Dictate Vascularization Potential in an Organ-Dependent Fashion

Zhang, M., Zhao, F., Zhu, Y., Brouwer, L. A., Van der Veen, H., Burgess, J. K. & Harmsen, M. C., 12-Jun-2024, In: ACS Applied Materials & Interfaces. 16, 23, p. 29930–29945 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

Fibroblasts alter the physical properties of dermal ECM-derived hydrogels to create a pro-angiogenic microenvironment

Zhang, M., Zhao, F., Zhang, X., Brouwer, L. A., Burgess, J. K. & Harmsen, M. C., Dec-2023, In: Materials Today Bio. 23, 13 p., 100842.

Research output: Contribution to journal › Article › Academic › peer-review

Autologous Lipofilling Improves Clinical Outcome in Patients With Symptomatic Dermal Scars Through Induction of a Pro-Regenerative Immune Response

Spiekman, M., Francia, D. L., Mossel, D. M., Brouwer, L. A., Diercks, G. F. H., Vermeulen, K. M., Folkertsma, M., Ghods, M., Kzhyshkowska, J., Klüter, H., Krenning, G., van der Lei, B. & Harmsen, M. C., Apr-2022, In: Aesthetic Surgery Journal. 42, 4, p. NP244–NP256 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

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ing. L.A. Brouwer

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