Skip to ContentSkip to Navigation
University of Groningenfounded in 1614  -  top 100 university
Close
About us Practical matters How to find us dr. C.A. (Charlotte) Oomen

dr. C.A. (Charlotte) Oomen

Faculty Funding Officer
Profile picture of dr. C.A. (Charlotte) Oomen
E-mail:
charlotte.oomen rug.nl

Previous Positions
  • Grant Advisor - Donders Center for Medical Neuroscience, RadboudUMC 2019-2021
  • Grant Advisor - Personal Grants, RadboudUMC 2018-2019
  • Researcher & Lecturer VU/UvA 2016-2018 in part funded by ZonMw Off Road personal grant
  • Postdoc RadboudUMC 2013-2016
  • Postdoc University of Cambridge (UK) 2010-2013
  • PhD University of Amsterdam (UvA) 2005-2010

Scientific Publications

1. Lim J., Souiki A., Ahmad P., Oomen C.A., Huis In 't Veld G.J., Lansink C.S., Pennartz C.M.A., Olcese U. Transient DREADD Manipulation of the Dorsal Dentate Gyrus in Rats Impairs Initial Learning of Place-Outcome Associations. Hippocampus. 2025 May;35(3):e70014. doi: 10.1002/hipo.70014. PMID: 40326013; PMCID: PMC12053149.
2. Sheppard P.A.S., Oomen C.A., Bussey T.J., Saksida L.M. The Granular Retrosplenial Cortex Is Necessary in Male Rats for Object-Location Associative Learning and Memory, But Not Spatial Working Memory or Visual Discrimination and Reversal, in the Touchscreen Operant Chamber. eNeuro. 2024 Jun 18;11(6):ENEURO.0120-24.2024. doi: 10.1523/ENEURO.0120-24.2024. PMID: 38844347; PMCID: PMC11208985.
3. Jager A., Dam S.A., Van Der Mierden S., Oomen C.A., Arias-Vasquez A., Buitelaar J.K., Kozicz T., Glennon J.C. Modulation of cognitive flexibility by reward and punishment in BALB/cJ and BALB/cByJ mice. Behav Brain Res. 2020 Jan 27;378:112294. doi: 10.1016/j.bbr.2019.112294. Epub 2019 Oct 15. PMID: 31626850.
4. van de Vondervoort I.I.G.M., Amiri H., Bruchhage M.M.K., Oomen C.A., Rustogi N., Cooper J.D., van Asten J.J.A., Heerschap A., Bahn S., Williams S.C.R., Buitelaar J.K., Poelmans G., Glennon J.C. Converging evidence points towards a role of insulin signaling in regulating compulsive behavior. Transl Psychiatry. 2019 Sep 12;9(1):225. doi: 10.1038/s41398-019-0559-6. PMID: 31515486; PMCID: PMC6742634.
5. Dam S.A., Jager A., Oomen C.A., Buitelaar J.K., Arias-Vasquez A., Glennon J.C. Inhibitory control in BALB/c mice sub-strains during extinction learning. Eur Neuropsychopharmacol. 2019 Apr;29(4):509-518. doi: 10.1016/j.euroneuro.2019.02.007. Epub 2019 Mar 6. PMID: 30851996.
6. Atsak P., Morena M., Schoenmaker C., Tabak E., Oomen C.A., Jamil S., Hill M.N., Roozendaal B. Glucocorticoid-endocannabinoid uncoupling mediates fear suppression deficits after early - Life stress. Psychoneuroendocrinology. 2018 May;91:41-49. doi: 10.1016/j.psyneuen.2018.02.021. Epub 2018 Feb 21. PMID: 29524763.
7. Benevento M.*, Oomen C.A.*, Horner A.E., Amiri H., Jacobs T., Pauwels C., Frega M., Kleefstra T., Kopanitsa M.V., Grant S.G., Bussey T.J., Saksida L.M., Van der Zee C.E., Van Bokhoven H., Glennon J.C., Kasri N.N. Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation. Scientific Reports, 2017, Jan 10; 7: 40284. Doi 10.1038/srep40284. *equal contribution
8. Hvoslef-Eide M., Oomen C.A. Adult neurogenesis and pattern separation in rodents: a critical evaluation of data, tasks and interpretation. Frontiers in Biology, 2016, 11(3) 168-181. DOI 10.1007/s11515-016-1406-2. Review
9.  Lucassen P.J., Oomen C.A. Stress, hippocampal neurogenesis and cognition: functional correlations. Frontiers in Biology, 2016, 11(3) 182-192. DOI 10.1007/s11515-016-1412-4. Review 
10.  Lucassen P.J., Oomen C.A., Naninck E.F.G., Fitzsimons C.P., van Dam A.M., Czeh B., Korosi A. Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation. Cold Spring Harbor Perspectives in Biology, 2015, Sep 1;7(9):a021303. doi: 10.1101/cshperspect.a021303. Review
11. Oomen C.A.*, Hvoslef-Eide M.*, Kofink D., Preusser F., Saksida L.M., Bussey T.J. A novel 2- and 3-choice touchscreen-based continuous trial-unique nonmatching-to-location task (cTUNL) sensitive to functional differences between dentate gyrus and CA3 subregions of the hippocampus. Psychopharmacology, 2015, DOI 10.1007/s00213-015-4019-6. *equal contribution
12. Hvoslef-Eide M.*, Oomen C.A.*, Fisher B.M., Heath C.J., Robbins T.W., Saksida L.M., Bussey T.J. Facilitation of spatial working memory performance following intra-prefrontal cortical administration of the adrenergic alpha1 agonist phenylephrine. Psychopharmacology, 2015, DOI 10.1007/s00213-015-4038-3 *equal contribution 
13. Kent B.A. Oomen C.A., Bekinschtein P., Saksida L.M., Bussey T.J. Cognitive enhancing effects of voluntary exercise, caloric restriction and environmental enrichment: a role for adult hippocampal neurogenesis and pattern separation? Current Opinion in Behavioral Sciences, 2015, DOI:10.1016/j.cobeha.2015.06.009. Review
14. Kim C.H., Romberg C., Hvoslef-Eide M., Oomen C.A., Mar A.C., Berthiaume A.A., Bussey T.J., Saksida L.M. Trial-unique, delayed nonmatching-to-location (TUNL) touchscreen testing for mice: Effects of dorsal hippocampal dysfunction. Psychopharmacology, 2015, DOI 10.1007/s00213-015-4017-8.
15. Howe W.M., Tierney P.L., Young D.A., Oomen C., Kozak R. MAM (E17) rodent developmental model of neuropsychiatric disease: disruptions in learning and dysregulation of nucleus accumbens dopamine release, but spared executive function. Psychopharmacology, 2015, DOI 10.1007/s00213-015-3955-5
16. Oomen C.A., Kent B.A., Bekinschtein P., Saksida L.M., Bussey T.J. Adult neurogenesis and its role in cognition. Wiley Interdisciplinary Reviews, 2014 Aug. doi: 10.1002/wcs.1304. Review.
17. Bekinschtein P., Kent B.A., Oomen C.A., Clemenson D., Gage F., Saksida L.M., Bussey T.J. Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories. Hippocampus, 2014 May doi: 10.1002/hipo.22304.
18. Oomen C.A., Hvoslef-Eide M., Heath C.J., Mar A.C., Horner A.E., Bussey T.J., Saksida L.M. The touchscreen operant platform for testing working memory and pattern separation in rats and mice. Nature Protocols, 2013 Oct;8(10):2006-21.
19. Horner A.E., Heath C.J., Hvoslef-Eide M., Kent B.A., Kim C.H., Nilsson S., Alsiö J., Oomen C.A., Holmes A., Saksida L.M., Bussey T.J. The touchscreen operant platform for testing learning and memory in rats and mice. Nature Protocols, 2013 Oct;8(10):1961-84.
20. Bekinschtein P., Kent B.A., Oomen C.A., Clemenson D., Gage F., Saksida L.M., Bussey T.J. BDNF in the dentate gyrus is required for consolidation of “pattern-separated” memories. Cell Reports, 2013 Nov 14;5(3):759-68.
21. Bussey T.J., Holmes A., Lyon L., Mar A.C., McAllister K.A., Nithianantharajah J., Oomen C.A., Saksida L.M. New translational assays for preclinical modelling of cognition in schizophrenia: The touchscreen testing method for mice and rats. Neuropharmacology, 2012; Mar;62(3):1191-203. Review.
22. Hu P., Oomen C., Van Dam A.M., Wester J., Zhou J.N, Joëls M., Lucassen P.J. A single-day treatment with mifepristone is sufficient to normalize chronic glucocorticoid treatment induced suppression of rat neurogenesis. PLoS One, 2012; 7(9):e46224.
23. Krugers H.J., Oomen C.A., Gumbs M., Li M., Velzing E.H., Joëls M., Lucassen P.J. Maternal deprivation and dendritic complexity in the basolateral amygdala. Neuropharmacology, 2012; Jan;62(1):534-7.
24. Korosi A., Naninck E.F., Oomen C.A., Schouten M., Krugers H., Fitzsimons C., Lucassen P.J. Early-life stress mediated modulation of adult neurogenesis and behavior. Behavioural Brain Research, 2012; Feb 14; 227(2):400-9. Review.
25. Bekinschtein P., Oomen C.A., Saksida L.M., Bussey T.J. Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable? Seminars in Cell & Developmental Biology, 2011; Jul;22(5):536-42. Review.
26. Van Bokhoven P., Oomen C.A., Hoogendijk W.J., Smit A.B., Lucassen P.J., Spijker S. Reduction in hippocampal neurogenesis after social defeat is long-lasting and responsive to late antidepressant treatment. European Journal of Neuroscience, 2011; May;33(10):1833-40.
27. Oomen C.A., Soeters H., Audureau N., Vermunt L., van Hasselt F.N., Manders E.M., Joëls M., Krugers H., Lucassen P.J. Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats. Psychopharmacology (Berl), 2011; Mar;214(1):249-60.
28. Oomen C.A., Soeters H., Audureau N., Vermunt L., van Hasselt F.N., Manders E.M., Joëls M., Lucassen P.J., Krugers H. Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high-stress conditions in adulthood. Journal of Neuroscience, 2010; May 12;30(19): 6635-45.
29. Lucassen P.J., Meerlo P., Naylor A.S., van Dam A.M., Dayer A.G., Fuchs E., Oomen C.A., Czéh B. (2010) Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action. European Neuropsychopharmacology, 2010; Jan; 20(1):1-17. Review.
30. Oomen C.A., Girardi C.E.N., Cahyadi R., Verbeek E.C., Krugers H., Joëls M., Lucassen P.J. Opposite effects of early maternal deprivation on neurogenesis in male versus female rats. PloS One, 2009; (4) 1, e3675.
31. Oomen C.A., Farkas E., Roman V., Van der Beek E.M., Luiten P.M.G., Meerlo P. Resveratrol preserves cerebrovascular density in aging mice. Frontiers in Aging Neuroscience, 2009; Dec 9;1:4.
32. Oomen C.A., Mayer J.L., Joëls M., de Kloet E.R., Lucassen P.J. Brief treatment with the GR antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress. European Journal of Neuroscience, 2007; (26), 3395-401.
33. Jarajapu Y.P., Oomen C., Uteshev V.V., Knot, H.J. Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated KV channel activation, independent of endothelium and cyclic AMP. European Journal of Pharmacology, 2006; 547, 116-124.
Last modified:04 March 2026 8.47 p.m.
Follow the UGfacebook linkedin rss instagram youtube
Set your cookie preferences. Read our privacy and cookie disclaimer for more information.