Molecular Microbiology- Publications

Nisa, I., Haroon, M., Driessen, A., Nijland, J., Rahman, H., Yasin, N., Hussain, M., Khan, T. A., Ali, A., Khan, S. A., & Qasim, M. (2022). Antimicrobial Resistance of Shigella flexneri in Pakistani Pediatric Population Reveals an Increased Trend of Third-Generation Cephalosporin Resistance. Current Microbiology, 79(4), [118]. https://doi.org/10.1007/s00284-022-02805-9

Zhang, X., Nijland, J. G., & Driessen, A. J. M. (2022). Combined roles of exporters in acetic acid tolerance in Saccharomyces cerevisiae. Biotechnology for Biofuels and Bioproducts, 15(1), [67]. https://doi.org/10.1186/s13068-022-02164-4

Chakraborty, P., Oosterhuis, D., Bonsignore, R., Casini, A., Olinga, P., & Scheffers, D-J. (2021). An organogold compound as potential antimicrobial agent against drug resistant bacteria: Initial mechanistic insights. ChemMedChem, 16(19), 3060-3070. https://doi.org/10.1002/cmdc.202100342

Polaquini, C. R., Marques, B. C., Ayusso, G. M., Morão, L. G., Sardi, J. C. O., Campos, D. L., Silva, I. C., Cavalca, L. B., Scheffers, D-J., Rosalen, P. L., Pavan, F. R., Ferreira, H., & Regasini, L. O. (2021). Antibacterial activity of a new monocarbonyl analog of curcumin MAC 4 is associated with divisome disruption. Bioorganic Chemistry, 109, [104668]. https://doi.org/10.1016/j.bioorg.2021.104668

Cavalca, L. B., Lahive, C. W., Gijsbers, F., Pavan, F. R., Scheffers, D-J., & Deuss, P. J. (2021). Benzenetriol-Derived Compounds against Citrus Canker. Molecules, 26(5), [1436]. https://doi.org/10.3390/molecules26051436

Nass, K. J., Ilie, I. M., Saller, M. J., Driessen, A. J. M., Caflisch, A., Kammerer, R. A., & Li, X. (2022). The role of the N-terminal amphipathic helix in bacterial YidC: Insights from functional studies, the crystal structure and molecular dynamics simulations. Biochimica et Biophysica Acta - Biomembranes, 1864(3), [183825]. https://doi.org/10.1016/j.bbamem.2021.183825

Exterkate, M., de Kok, N. A. W., Andringa, R. L. H., Wolbert, N. H. J., Minnaard, A. J., & Driessen, A. J. M. (2021). A promiscuous archaeal cardiolipin synthase enables construction of diverse natural and unnatural phospholipids. The Journal of Biological Chemistry, 296, [100691]. https://doi.org/10.1016/j.jbc.2021.100691

Minnaard, A. J., Andringa, R., de Kok, N., & Driessen, A. (2021). A Unified Approach for the Total Synthesis of cyclo-Archaeol, iso-Caldarchaeol, Caldarchaeol, and Mycoketide. Angewandte Chemie (International ed. in English), 60(32), 17497-17503. https://doi.org/10.1002/anie.202104759

de Kok, N. A. W., Exterkate, M., Andringa, R. L. H., Minnaard, A. J., & Driessen, A. J. M. (2021). A versatile method to separate complex lipid mixtures using 1-butanol as eluent in a reverse-phase UHPLC-ESI-MS system. Chemistry and physics of lipids, 240, [105125]. https://doi.org/10.1016/j.chemphyslip.2021.105125

Mózsik, L., Hoekzema, M., de Kok, N. A. W., Bovenberg, R. A. L., Nygård, Y., & Driessen, A. J. M. (2021). Author Correction: CRISPR-based transcriptional activation tool for silent genes in filamentous fungi (Scientific Reports, (2021), 11, 1, (1118), 10.1038/s41598-020-80864-3). Scientific Reports, 11(1), [20129]. https://doi.org/10.1038/s41598-021-99654-6

Seinen, A-B., Spakman, D., van Oijen, A. M., & Driessen, A. J. M. (2021). Cellular dynamics of the SecA ATPase at the single molecule level. Scientific Reports, 11(1), [1433]. https://doi.org/10.1038/s41598-021-81081-2

Ren, S., de Kok, N. A. W., Gu, Y., Yan, W., Sun, Q., Chen, Y., He, J., Tian, L., Andringa, R. L. H., Zhu, X., Tang, M., Qi, S., Xu, H., Ren, H., Fu, X., Minnaard, A. J., Yang, S., Zhang, W., Li, W., ... Cheng, W. (2021). Correction: Structural and Functional Insights into an Archaeal Lipid Synthase. Cell reports, 35(7), [109182]. https://doi.org/10.1016/j.celrep.2021.109182

Mózsik, L., Hoekzema, M., de Kok, N. A. W., Bovenberg, R. A. L., Nygård, Y., & Driessen, A. J. M. (2021). CRISPR-based transcriptional activation tool for silent genes in filamentous fungi. Scientific Reports, 11(1), [1118]. https://doi.org/10.1038/s41598-020-80864-3

Iacovelli, R., Mózsik, L., Bovenberg, R. A. L., & Driessen, A. J. M. (2021). Identification of a conserved N-terminal domain in the first module of ACV synthetases. MicrobiologyOpen, 10(1), [e1145]. https://doi.org/10.1002/mbo3.1145

Mózsik, L., Pohl, C., Meyer, V., Bovenberg, R. A. L., Nygård, Y., & Driessen, A. J. M. (2021). Modular Synthetic Biology Toolkit for Filamentous Fungi. ACS Synthetic Biology, 10(11), 2850–2861. https://doi.org/10.1021/acssynbio.1c00260

Iacovelli, R., Bovenberg, R. A. L., & Driessen, A. J. M. (2021). Nonribosomal peptide synthetases and their biotechnological potential in Penicillium rubens. Journal of Industrial Microbiology & Biotechnology, 48(7-8), [kuab045]. https://doi.org/10.1093/jimb/kuab045

Nisa, I., Qasim, M., Driessen, A., Nijland, J., Rafiullah, Ali, A., Mirza, M. R., Khan, M. A., Khan, T. A., Jalal, A., & Rahman, H. (2021). Prevalence and associated risk factors of Shigella flexneri isolated from drinking water and retail raw foods in Peshawar, Pakistan. Journal of food science, 86(6), 2579-2589. https://doi.org/10.1111/1750-3841.15777

Koch, S., Seinen, A. B., Kamel, M., Kuckla, D., Monzel, C., Kedrov, A., & Driessen, A. J. M. (2021). Single-molecule analysis of dynamics and interactions of the SecYEG translocon. Febs Journal, 288(7), 2203-2221. https://doi.org/10.1111/febs.15596

Nisa, I., Qasim, M., Driessen, A., Nijland, J., Adnan, F., Shuja, M. N., & Rahman, H. (2021). Virulence profiling of Shigella flexneri and emergence of serotype 2b as a highly virulent shigellosis causing strain in Pakistan. Infection genetics and evolution, 93, [104922]. https://doi.org/10.1016/j.meegid.2021.104922

Li, Z., Chakraborty, P., de Vries, R. H., Song, C., Zhao, X., Roelfes, G., Scheffers, D-J., & Kuipers, O. P. (2020). Characterization of two relacidines belonging to a novel class of circular lipopeptides that act against Gram-negative bacterial pathogens. Environmental Microbiology, 22(12), 5125-5136. https://doi.org/10.1111/1462-2920.15145

Zielińska, A., Savietto, A., de Sousa Borges, A., Martinez, D., Berbon, M., Roelofsen, J. R., Hartman, A. M., de Boer, R., Van der Klei, I. J., Hirsch, A. K., Habenstein, B., Bramkamp, M., & Scheffers, D-J. (2020). Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement. eLife, 9, 1-21. [e57179]. https://doi.org/10.7554/eLife.57179

Morao, L. G., Lorenzoni, A. S. G., Chakraborty, P., Ayusso, G. M., Cavalca, L. B., Santos, M. B., Marques, B. C., Dilarri, G., Zamuner, C., Regasini, L. O., Ferreira, H., & Scheffers, D-J. (2020). Investigating the Modes of Action of the Antimicrobial Chalcones BC1 and T9A. Molecules, 25(20), [4596]. https://doi.org/10.3390/molecules25204596

Li, Z., de Vries, R. H., Chakraborty, P., Song, C., Zhao, X., Scheffers, D-J., Roelfes, G., & Kuipers, O. P. (2020). Novel modifications of nonribosomal peptides from Brevibacillus laterosporus MG64 and investigation of their mode of action. Applied and environmental microbiology, 86(24), 1-14. [e01981-20]. https://doi.org/10.1128/AEM.01981-20

Morales Angeles, D., & Scheffers, D-J. (2020). The Cell Wall of Bacillus subtilis. Current Issues in Molecular Biology, 41, 539-596. https://doi.org/10.21775/cimb.041.539

Nijland, J. G., Shin, H. Y., Dore, E., Rudinatha, D., de Waal, P. P., & Driessen, A. J. M. (2021). D-glucose overflow metabolism in an evolutionary engineered high-performance D-xylose consuming Saccharomyces cerevisiae strain. Fems Yeast Research, 21(1), [foaa062]. https://doi.org/10.1093/femsyr/foaa062

Pohl, C., Polli, F., Schütze, T., Viggiano, A., Mózsik, L., Jung, S., de Vries, M., Bovenberg, R. A. L., Meyer, V., & Driessen, A. J. M. (2020). A Penicillium rubens platform strain for secondary metabolite production. Scientific Reports, 10(1), [7630]. https://doi.org/10.1038/s41598-020-64893-6

Driessen, A. J. M., & Wei, Y-Q. (2020). Announcing Molecular Biomedicine. Molecular biomedicine, 1(1), [1]. https://doi.org/10.1186/s43556-020-00003-2

Nisa, I., Haroon, M., Qasim, M., Driessen, A., Nijland, J., Yasin, N., Jalal, A., Ali, N., Ullah, W., Khan, T. A., Begum, A., & Rahman, H. (2020). Association of Serotype With Antimicrobial Resistance Patterns Among Shigella flexneri Isolates From Pakistan: The Importance of Serotype 2b. Pediatric infectious disease journal, 39(11), E352-E358. https://doi.org/10.1097/INF.0000000000002791

Iacovelli, R., Zwahlen, R. D., Bovenberg, R. A. L., & Driessen, A. J. M. (2020). Biochemical characterization of the Nocardia lactamdurans ACV synthetase. PLoS ONE, 15(4), [e0231290]. https://doi.org/10.1371/journal.pone.0231290

Nijland, J. G., & Driessen, A. J. M. (2020). Engineering of Pentose Transport in Saccharomyces cerevisiae for Biotechnological Applications. Frontiers in Bioengineering and Biotechnology, 7, [464]. https://doi.org/10.3389/fbioe.2019.00464

Nisa, I., Qasim, M., Driessen, A., Nijland, J., Bari, F., Haroon, M., Rahman, H., Yasin, N., Khan, T. A., Hussain, M., & Hussain, W. (2020). Molecular epidemiology of Shigella flexneri isolated from pediatrics in a diarrhea-endemic area of Khyber Pakhtunkhwa, Pakistan. European Journal of Clinical Microbiology & Infectious Diseases, 39(5), 971-985. https://doi.org/10.1007/s10096-020-03811-0

Ren, S., de Kok, N. A. W., Gu, Y., Yan, W., Sun, Q., Chen, Y., He, J., Tian, L., Andringa, R. L. H., Zhu, X., Tang, M., Qi, S., Xu, H., Ren, H., Fu, X., Minnaard, A. J., Yang, S., Zhang, W., Li, W., ... Cheng, W. (2020). Structural and Functional Insights into an Archaeal Lipid Synthase. Cell reports, 33(3), [108294]. https://doi.org/10.1016/j.celrep.2020.108294

Morales Angeles, D., Macia Valero, A., Bohorquez Suarez, L., & Scheffers, D-J. (2020). The PASTA domains of Bacillus subtilis PBP2B stabilize the interaction of PBP2B with DivIB. Microbiology, 166(9), 826–836. [000957]. https://doi.org/10.1099/mic.0.000957

Polaquini, C. R., Morão, L. G., Nazaré, A. C., Torrezan, G. S., Dilarri, G., Cavalca, L. B., Campos, D. L., Silva, I. C., Pereira, J. A., Scheffers, D-J., Duque, C., Pavan, F. R., Ferreira, H., & Regasini, L. O. (2019). Antibacterial activity of 3,3'-dihydroxycurcumin (DHC) is associated with membrane perturbation. Bioorganic Chemistry, 90, [103031]. https://doi.org/10.1016/j.bioorg.2019.103031

Wu, M., Crismaru, C. G., Salo, O., Bovenberg, R. A. L., & Driessen, A. J. M. (2020). Impact of classical strain improvement of penicillium rubens on amino acid metabolism during β-Lactam production. Applied and environmental microbiology, 86(3), [e01561]. https://doi.org/10.1128/AEM.01561-19

Zwahlen, R., Pohl, C., Bovenberg, R. A. L., & Driessen, A. J. M. (2019). Bacterial MbtH-like proteins stimulate nonribosomal peptide synthetase-derived secondary metabolism in the filamentous fungi. ACS Synthetic Biology, 8(8), 1776-1787. https://doi.org/10.1021/acssynbio.9b00106

Exterkate, M., & Driessen, A. J. M. (2019). Continuous expansion of a synthetic minimal cellular membrane. Emerging topics in life sciences, 3(5), 543-549. https://doi.org/10.1042/ETLS20190020

Hansen, M., Hille, J., Szymanski, W., Driessen, A., & Feringa, B. L. (2019). Easily Accessible, Highly Potent, Photocontrolled Modulators of Bacterial Communication. Chem, 5(5), 1293-1301. https://doi.org/10.1016/j.chempr.2019.03.005

Nijland, J. G., Li, X., Shin, H. Y., de Waal, P. P., & Driessen, A. J. M. (2019). Efficient, D-glucose insensitive, growth on D-xylose by an evolutionary engineered Saccharomyces cerevisiae strain. Fems Yeast Research, 19(8), [foz083]. https://doi.org/10.1093/femsyr/foz083

Komarudin, A. G., & Driessen, A. J. M. (2019). SecA-Mediated Protein Translocation through the SecYEG Channel. Microbiology Spectrum, 7(4). https://doi.org/10.1128/microbiolspec.PSIB-0028-2019

Seinen, A-B., & Driessen, A. J. M. (2019). Single-Molecule Studies on the Protein Translocon. Annual Review of Biophysics, 48, 185-207. https://doi.org/10.1146/annurev-biophys-052118-115352

Mózsik, L., Büttel, Z., Bovenberg, R. A. L., Driessen, A. J. M., & Nygård, Y. (2019). Synthetic control devices for gene regulation in Penicillium chrysogenum. Microbial Cell Factories, 18(1), [203]. https://doi.org/10.1186/s12934-019-1253-3

Exterkate, M., & Driessen, A. J. M. (2019). Synthetic Minimal Cell: Self-Reproduction of the Boundary Layer. ACS Omega, 4(3), 5293-5303. [02955]. https://doi.org/10.1021/acsomega.8b02955

Koch, S., Exterkate, M., López, C. A., Patro, M., Marrink, S. J., & Driessen, A. J. M. (2019). Two distinct anionic phospholipid-dependent events involved in SecA-mediated protein translocation. Biochimica et Biophysica Acta - Biomembranes, 1861(11), [183035]. https://doi.org/10.1016/j.bbamem.2019.183035

Morão, L. G., Polaquini, C. R., Kopacz, M., Torrezan, G. S., Ayusso, G. M., Dilarri, G., Cavalca, L. B., Zielińska, A., Scheffers, D-J., Regasini, L. O., & Ferreira, H. (2019). A simplified curcumin targets the membrane of Bacillus subtilis. MicrobiologyOpen, 8(4), [683]. https://doi.org/10.1002/mbo3.683

Kopacz, M. M., Lorenzoni, A. S. G., Polaquini, C. R., Regasini, L. O., & Scheffers, D-J. (2019). Purification and characterization of FtsZ from the citrus canker pathogen Xanthomonas citri subsp. citri. MicrobiologyOpen, 8(5), [e00706]. https://doi.org/10.1002/mbo3.706

Savietto, A., Polaquini, C. R., Kopacz, M., Scheffers, D-J., Marques, B. C., Regasini, L. O., & Ferreira, H. (2018). Antibacterial activity of monoacetylated alkyl gallates against Xanthomonas citri subsp citri. Archives of Microbiology, 200(6), 929-937. https://doi.org/10.1007/s00203-018-1502-6

Nazaré, A. C., Polaquini, C. R., Cavalca, L. B., Anselmo, D. B., Saiki, M. D. F. C., Monteiro, D. A., Zielinska, A., Rahal, P., Gomes, E., Scheffers, D-J., Ferreira, H., & Regasini, L. O. (2018). Design of Antibacterial Agents: Alkyl Dihydroxybenzoates against Xanthomonas citri subsp. citri. International Journal of Molecular Sciences, 19(10), 1-15. https://doi.org/10.3390/ijms19103050

Baker, L. A., Sinnige, T., Schellenberger, P., de Keyzer, J., Siebert, C. A., Driessen, A. J. M., Baldus, M., & Grünewald, K. (2018). Combined 1H-Detected Solid-State NMR Spectroscopy and Electron Cryotomography to Study Membrane Proteins across Resolutions in Native Environments. Structure, 26(1), 161-170. [j.str.2017.11.011]. https://doi.org/10.1016/j.str.2017.11.011

Caforio, A., Siliakus, M. F., Exterkate, M., Jain, S., Jumde, V. R., Andringa, R. L. H., Kengen, S. W. M., Minnaard, A. J., Driessen, A. J. M., & van der Oost, J. (2018). Converting into an archaebacterium with a hybrid heterochiral membrane. Proceedings of the National Academy of Sciences of the United States of America, 115(14), 3704-3709. [pnas.1721604115]. https://doi.org/10.1073/pnas.1721604115

Guzman-Chavez, F., Salo, O., Samol, M., Ries, M., Kuipers, J., Bovenberg, R. A. L., Vreeken, R. J., & Driessen, A. J. M. (2018). Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum. MicrobiologyOpen, 7(5), [e00598]. https://doi.org/10.1002/mbo3.598

Guzman-Chavez, F., Zwahlen, R. D., Bovenberg, R. A. L., & Driessen, A. J. M. (2018). Engineering of the Filamentous Fungus Penicillium chrysogenum as Cell Factory for Natural Products. Frontiers in Microbiology, 9, [2768]. https://doi.org/10.3389/fmicb.2018.02768

Grijseels, S., Pohl, C., Nielsen, J. C., Wasil, Z., Nygård, Y., Nielsen, J., Frisvad, J. C., Nielsen, K. F., Workman, M., Larsen, T. O., Driessen, A. J. M., & Frandsen, R. J. N. (2018). Identification of the decumbenone biosynthetic gene cluster in and the importance for production of calbistrin. Fungal Biology and Biotechnology, 5, [18]. https://doi.org/10.1186/s40694-018-0063-4

Verhoeven, M. D., Bracher, J. M., Nijland, J. G., Bouwknegt, J., Daran, J-M. G., Driessen, A. J. M., van Maris, A. J. A., & Pronk, J. T. (2018). Laboratory evolution of a glucose-phosphorylation-deficient, arabinose-fermenting S. cerevisiae strain reveals mutations in GAL2 that enable glucose-insensitive l-arabinose uptake. Fems Yeast Research, 18(6). https://doi.org/10.1093/femsyr/foy062

Bracher, J. M., Verhoeven, M. D., Wisselink, H. W., Crimi, B., Nijland, J. G., Driessen, A. J. M., Klaassen, P., van Maris, A. J. A., Daran, J-M. G., & Pronk, J. T. (2018). The Penicillum chrysogenum transporter PcAraT enables high-affinity, glucose-insensitive L-arabinose transport in Saccharomyces cerevisiae. Biotechnology for Biofuels, 11, [63]. https://doi.org/10.1186/s13068-018-1047-6

Dockerty, P., Edens, J. G., Tol, M. B., Morales Angeles, D., Domenech Pena, A., Liu, Y., Hirsch, A. K. H., Veening, J-W., Scheffers, D-J., & Witte, M. D. (2017). Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins. Organic & Biomolecular Chemistry, 15(4), 894-910. https://doi.org/10.1039/c6ob01664b

Król, E., de Sousa Borges, A., Kopacz, M., & Scheffers, D-J. (2017). Metal-dependent SpoIIE oligomerization stabilizes FtsZ during asymmetric division in Bacillus subtilis. PLoS ONE, 12(3), [e0174713]. https://doi.org/10.1371/journal.pone.0174713

Morales Angeles, D., Liu, Y., Hartman, A. M., Borisova, M., de Sousa Borges, A., de Kok, N., Beilharz, K., Veening, J-W., Mayer, C., Hirsch, A. K. H., & Scheffers, D-J. (2017). Pentapeptide-rich peptidoglycan at the Bacillus subtilis cell-division site. Molecular Microbiology, 104(2), 319-333. https://doi.org/10.1111/mmi.13629

Soibelmann Glock Lorenzoni, A., Dantas, G., Bergsma, T., Ferreira, H., & Scheffers, D. (2017). Xanthomonas citri MinC Oscillates from Pole to Pole to Ensure Proper Cell Division and Shape. Frontiers in Microbiology, 8, 1-12. [1352]. https://doi.org/10.3389/fmicb.2017.01352

Exterkate, M., Caforio, A., Stuart, M. C. A., & Driessen, A. J. M. (2018). Growing membranes in vitro by continuous phospholipid biosynthesis from free fatty acids. ACS Synthetic Biology, 7(1), 153-165. [acssynbio.7b00265]. https://doi.org/10.1021/acssynbio.7b00265

Nijland, J. G., Shin, H. Y., de Waal, P. P., Klaassen, P., & Driessen, A. J. M. (2018). Increased xylose affinity of Hxt2 through gene shuffling of hexose transporters in Saccharomyces cerevisiae. Journal of Applied Microbiology, 124(2), 503-510. [jam.13670]. https://doi.org/10.1111/jam.13670

Viggiano, A., Salo, O., Ali, H., Szymanski, W., Lankhorst, P. P., Nygård, Y., Bovenberg, R. A. L., & Driessen, A. J. M. (2018). Pathway for the Biosynthesis of the Pigment Chrysogine by Penicillium chrysogenum. Applied and environmental microbiology, 84(4), [e02246-17]. https://doi.org/10.1128/AEM.02246-17

Caforio, A., & Driessen, A. J. M. (2017). Archaeal phospholipids: Structural properties and biosynthesis. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862(11), 1325-1339. https://doi.org/10.1016/j.bbalip.2016.12.006

Nijland, J. G., Shin, H. Y., Boender, L. G. M., de Waal, P. P., Klaassen, P., & Driessen, A. J. M. (2017). Improved xylose metabolism by a CYC8 mutant of Saccharomyces cerevisiae. Applied and environmental microbiology, 83(11), [e00095-17]. https://doi.org/10.1128/AEM.00095-17

Derntl, C., Guzmán-Chávez, F., Mello-de-Sousa, T. M., Busse, H-J., Driessen, A. J. M., Mach, R. L., & Mach-Aigner, A. R. (2017). In Vivo Study of the Sorbicillinoid Gene Cluster in Trichoderma reesei. Frontiers in Microbiology, 8, [2037]. https://doi.org/10.3389/fmicb.2017.02037

Guzmán-Chávez, F., Salo, O., Nygård, Y., Lankhorst, P. P., Bovenberg, R. A. L., & Driessen, A. J. M. (2017). Mechanism and regulation of sorbicillin biosynthesis by Penicillium chrysogenum. Microbial Biotechnology, 10(4), 958-968. https://doi.org/10.1111/1751-7915.12736

Wegener, M., Hansen, M. J., Driessen, A. J. M., Szymanski, W., & Feringa, B. L. (2017). Photocontrol of Antibacterial Activity: Shifting from UV to Red Light Activation. Journal of the American Chemical Society, 139(49), 17979-17986. https://doi.org/10.1021/jacs.7b09281

Ren, S., Caforio, A., Yang, Q., Sun, B., Yu, F., Zhu, X., Wang, J., Dou, C., Fu, Q., Huang, N., Sun, Q., Nie, C., Qi, S., Gong, X., He, J., Wei, Y., Driessen, A. J. M., & Cheng, W. (2017). Structural and mechanistic insights into the biosynthesis of CDP-archaeol in membranes. Cell research, 27, 1378-1391. [cr.2017.122]. https://doi.org/10.1038/cr.2017.122

Shin, H. Y., Nijland, J. G., de Waal, P. P., & Driessen, A. J. M. (2017). The Amino-Terminal Tail of Hxt11 Confers Membrane Stability to the Hxt2 Sugar Transporter and Improves Xylose Fermentation in the Presence of Acetic Acid. Biotechnology and Bioengineering, 114(9), 1937-1945. https://doi.org/10.1002/bit.26322

de Sousa Borges, A., & Scheffers, D-J. (2016). Bacterial dynamin as a membrane puncture repair kit. Environmental Microbiology, 18(8), 2298-2301. https://doi.org/10.1111/1462-2920.13218

Pereira, A. R., Hsin, J., Król, E., Tavares, A. C., Flores, P., Hoiczyk, E., Ng, N., Dajkovic, A., Brun, Y. V., VanNieuwenhze, M. S., Roemer, T., Carballido-Lopez, R., Scheffers, D-J., Huang, K. C., & Pinho, M. G. (2016). FtsZ-Dependent Elongation of a Coccoid Bacterium. Mbio, 7(5), 1-9. [e00908-16 ]. https://doi.org/10.1128/mBio.00908-16

van Wolferen, M., Ajon, M., Driessen, A. J. M., & Albers, S-V. (2016). Corrigendum: Molecular analysis of the UV-inducible pili operon from Sulfolobus acidocaldarius (vol 2, pg 928, 2013). MicrobiologyOpen, 5(6), 1085-1085. https://doi.org/10.1002/mbo3.426

Pohl, C., Kiel, J. A. K. W., Driessen, A. J. M., Bovenberg, R. A. L., & Nygård, Y. (2016). CRISPR/Cas9 based genome editing of Penicillium chrysogenum. ACS Synthetic Biology, 5(7), 754-764. [6b00082]. https://doi.org/10.1021/acssynbio.6b00082

Salo, O., Guzmán-Chávez, F., Ries, M. I., Lankhorst, P. P., Bovenberg, R. A. L., Vreeken, R. J., & Driessen, A. J. M. (2016). Identification of a polyketide synthase involved in sorbicillin biosynthesis by Penicillium chrysogenum. Applied and environmental microbiology, 82(13), 3971-3978. [00350-00316]. https://doi.org/10.1128/AEM.00350-16

Nijland, J. G., Vos, E., Shin, H. Y., de Waal, P. P., Klaassen, P., & Driessen, A. J. M. (2016). Improving pentose fermentation by preventing ubiquitination of hexose transporters in Saccharomyces cerevisiae. Biotechnology for Biofuels, 9(158), [158]. https://doi.org/10.1186/s13068-016-0573-3

Koch, S., de Wit, J. G., Vos, I., Birkner, J. P., Gordiichuk, P., Herrmann, A., van Oijen, A. M., & Driessen, A. J. M. (2016). Lipids activate SecA for high affinity binding to the SecYEG complex. The Journal of Biological Chemistry, 291(43), 22534-22543. https://doi.org/10.1074/jbc.M116.743831

Trip, E. N., & Scheffers, D-J. (2015). A 1 MDa protein complex containing critical components of the Escherichia coli divisome. Scientific Reports, 5, [18190]. https://doi.org/10.1038/srep18190

Krol, E., de Sousa Borges, A., da Silva, I., Polaquini, C., Regasini, L., Ferreira, H., & Scheffers, D. (2015). Antibacterial activity of alkyl gallates is a combination of direct targeting of FtsZ and permeabilization of bacterial membranes. Frontiers in Microbiology, 6, [390]. https://doi.org/10.3389/fmicb.2015.00390

Silva, I., Pavan, F. R., Polaquini, C., Regasini, L. O., Scheffers, D. -J., & Ferreira, H. (2015). Assessment of cyto/genotoxicity of the antibacterial heptyl gallate in HepG2 cells and the possible target in bacteria. Toxicology Letters, 238(2, Supplement), S328-S328. https://doi.org/10.1016/j.toxlet.2015.08.935

Tol, M. B., Angeles, D. M., & Scheffers, D-J. (2015). In vivo cluster formation of nisin and Lipid II is correlated with membrane depolarization. Antimicrobial Agents and Chemotherapy, 59(6), 3683-3686. https://doi.org/10.1128/AAC.04781-14

Scheffers, D-J., & Tol, M. B. (2015). LipidII: Just Another Brick in the Wall? PLoS Pathogens, 11(12), [e1005213]. https://doi.org/10.1371/journal.ppat.1005213

de Sousa Borges, A., de Keyzer, J., Driessen, A. J. M., & Scheffers, D-J. (2015). The Escherichia coli membrane protein insertase YidC assists in the biogenesis of Penicillin Binding Proteins. Journal of Bacteriology, 197, 1444-1450. https://doi.org/10.1128/JB.02556-14

Polli, F., Meijrink, B., Bovenberg, R. A. L., & Driessen, A. J. M. (2016). New promoters for strain engineering of Penicillium chrysogenum. Fungal Genetics and Biology, 89, 62-71. https://doi.org/10.1016/j.fgb.2015.12.003

Ouchaou, K., Maire, F., Salo, O., Ali, H., Hankemeier, T., van der Marel, G. A., Filippov, D. V., Bovenberg, R. A. L., Vreeken, R. J., Driessen, A. J. M., & Overkleeft, H. S. (2015). A Mutasynthesis Approach with a Penicillium chrysogenum ΔroqA Strain Yields New Roquefortine D Analogues. ChemBioChem, 16, 915-923. https://doi.org/10.1002/cbic.201402686

Shin, H. Y., Nijland, J. G., de Waal, P. P., de Jong, R. M., Klaassen, P., & Driessen, A. J. M. (2015). An engineered cryptic Hxt11 sugar transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae. Biotechnology for Biofuels, 8(176). https://doi.org/10.1186/s13068-015-0360-6

Velema, W. A., van der Berg, J. P., Szymanski, W., Driessen, A. J. M., & Feringa, B. L. (2015). Bacterial patterning controlled by light exposure. Organic & Biomolecular Chemistry, 13(6), 1639-1642. https://doi.org/10.1039/c4ob02483d

van der Berg, J. P., Madoori, P. K., Komarudin, A. G., Thunnissen, A-M., & Driessen, A. J. M. (2015). Binding of the Lactococcal Drug Dependent Transcriptional Regulator LmrR to Its Ligands and Responsive Promoter Regions. PLoS ONE, 10(8), [e0135467]. https://doi.org/10.1371/journal.pone.0135467

Prabudiansyah, I., Kusters, I., Caforio, A., & Driessen, A. J. M. (2015). Characterization of the annular lipid shell of the Sec translocon. Biochimica et biophysica acta, 1848(10, Part A), 2050-2056. https://doi.org/10.1016/j.bbamem.2015.06.024

Velema, W. A., Hansen, M. J., Lerch, M. M., Driessen, A. J. M., Szymanski, W., & Feringa, B. L. (2015). Ciprofloxacin-Photoswitch Conjugates: A Facile Strategy for Photopharmacology. BIOCONJUGATE CHEMISTRY, 26(12), 2592-2597. https://doi.org/10.1021/acs.bioconjchem.5b00591

Van der Berg, J. P., Velema, W. A., Szymanski, W., Driessen, A. J. M., & Feringa, B. L. (2015). Controlling the activity of quorum sensing autoinducers with light. Chemical Science, 6(6), 3593-3598. https://doi.org/10.1039/c5sc00215j

Caforio, A., Jain, S., Fodran, P., Siliakus, M., Minnaard, A. J., van der Oost, J., & Driessen, A. J. M. (2015). Formation of the ether lipids archaetidylglycerol and archaetidylethanolamine in Escherichia coli. Biochemical Journal, 470(3), 343-355. [20150626]. https://doi.org/10.1042/BJ20150626

Salo, O. V., Ries, M., Medema, M. H., Lankhorst, P. P., Vreeken, R. J., Bovenberg, R. A. L., & Driessen, A. J. M. (2015). Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum. BMC Genomics, 16(1), [937]. https://doi.org/10.1186/s12864-015-2154-4

Reznicek, O., Facey, S. J., de Waal, P. P., Teunissen, A. W. R. H., de Bont, J. A. M., Nijland, J. G., Driessen, A. J. M., & Hauer, B. (2015). Improved xylose uptake in Saccharomyces cerevisiae due to directed evolution of galactose permease Gal2 for sugar co-consumption. Journal of Applied Microbiology, 119, 99-111. https://doi.org/10.1111/jam.12825

Driessen, A. J. M., & Poolman, B. (2015). In memoriam: Wilhelmus Nicolaas Konings (1937-2014). Extremophiles, 19, 233-234. https://doi.org/10.1007/s00792-015-0736-3

Prabudiansyah, I., Kusters, I., & Driessen, A. J. M. (2015). In Vitro Interaction of the Housekeeping SecA1 with the Accessory SecA2 Protein of Mycobacterium tuberculosis. PLoS ONE, 10(6), [e0128788]. https://doi.org/10.1371/journal.pone.0128788

Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., de Bruijn, I., Chooi, Y. H., Claesen, J., Coates, R. C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A., ... Glöckner, F. O. (2015). Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology, 11(9), 625-631. https://doi.org/10.1038/nchembio.1890

Geng, Y., Kedrov, A., Caumanns, J. J., Crevenna, A. H., Lamb, D. C., Beckmann, R., & Driessen, A. J. M. (2015). Role of the cytosolic loop C2 and the C-terminus of YidC in ribosome binding and insertion activity. The Journal of Biological Chemistry, 290, 17250-17261. https://doi.org/10.1074/jbc.M115.650309

Bos, J., Browne, W. R., Driessen, A. J. M., & Roelfes, G. (2015). Supramolecular Assembly of Artificial Metalloenzymes Based on the Dimeric Protein LmrR as Promiscuous Scaffold. Journal of the American Chemical Society, 137(31), 9796-9799. https://doi.org/10.1021/jacs.5b05790

Yang, N., & Driessen, A. J. M. (2015). The saci_2123 gene of the hyperthermoacidophile Sulfolobus acidocaldarius encodes an ATP-binding cassette multidrug transporter. Extremophiles, 19(1), 101-108. https://doi.org/10.1007/s00792-014-0688-z

Geng, Y., Keyzer, J. D., Scheffers, D-J., & Driessen, A. J. M. (2014). Defining the Region of Bacillus subtilis SpoIIIJ That Is Essential for Its Sporulation-Specific Function. Journal of Bacteriology, 196(7), 1318-1324. https://doi.org/10.1128/JB.01084-13

Ali, H., Ries, M. I., Lankhorst, P. P., van der Hoeven, R. A. M., Schouten, O. L., Noga, M., Hankemeier, T., van Peij, N. N. M. E., Bovenberg, R. A. L., Vreeken, R. J., & Driessen, A. J. M. (2014). A Non-Canonical NRPS Is Involved in the Synthesis of Fungisporin and Related Hydrophobic Cyclic Tetrapeptides in Penicillium chrysogenum. PLoS ONE, 9(6), [e98212]. https://doi.org/10.1371/journal.pone.0098212

Jain, S., Caforio, A., & Driessen, A. J. M. (2014). Biosynthesis of archaeal membrane ether lipids. Frontiers in Microbiology, 5, [641]. https://doi.org/10.3389/fmicb.2014.00641

Yang, N., & Driessen, A. J. M. (2014). Deletion of cdvB paralogous genes of Sulfolobus acidocaldarius impairs cell division. Extremophiles, 18(2), 331-339. https://doi.org/10.1007/s00792-013-0618-5

Nijland, J. G., Shin, H. Y., de Jong, R. M., De Waal, P. P., Klaassen, P., & Driessen, A. J. M. (2014). Engineering of an endogenous hexose transporter into a specific D-xylose transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae. Biotechnology for Biofuels, 7(168), [168]. https://doi.org/10.1186/s13068-014-0168-9

Jain, S., Caforio, A., Fodran, P., Lolkema, J. S., Minnaard, A. J., & Driessen, A. J. M. (2014). Identification of CDP-Archaeol Synthase, a Missing Link of Ether Lipid Biosynthesis in Archaea. Chemistry & Biology, 21(10), 1392-1401. https://doi.org/10.1016/j.chembiol.2014.07.022

Kusters, I., van Oijen, A. M., & Driessen, A. J. M. (2014). Membrane-on-a-Chip: Microstructured Silicon/Silicon-Dioxide Chips for High-Throughput Screening of Membrane Transport and Viral Membrane Fusion. Acs Nano, 8(4), 3380-3392. https://doi.org/10.1021/nn405884a

Driessen, A., Kaback, H. R., Poolman, B., & Walker, J. E. (2014). Obituary: Wilhelmus Nicolaas Konings (1937-2014). Biochemist e-volution, 36(6), 42-43.

Velema, W. A., van der Berg, J. P., Szymanski, W., Driessen, A. J. M., & Feringa, B. L. (2014). Orthogonal Control of Antibacterial Activity with Light. ACS chemical biology, 9(9), 1969-1974. https://doi.org/10.1021/cb500313f

Trip, E. N., Veening, J-W., Stewart, E. J., Errington, J., & Scheffers, D-J. (2013). Balanced transcription of cell division genes in Bacillus subtilis as revealed by single cell analysis. Environmental Microbiology, 15(12), 3196-3209. https://doi.org/10.1111/1462-2920.12148

Boekema, E. J., Scheffers, D-J., van Bezouwen, L. S., Bolhuis, H., & Folea, I. M. (2013). Focus on Membrane Differentiation and Membrane Domains in the Prokaryotic Cell. Journal of Molecular Microbiology and Biotechnology, 23(4-5), 345-356. https://doi.org/10.1159/000351361

Król, E., & Scheffers, D-J. (2013). FtsZ Polymerization Assays: Simple Protocols and Considerations. Journal of Visualized Experiments, (81), e50844-1-e50844-13. https://doi.org/10.3791/50844

Ballesteros-Plaza, D., Holguera, I., Scheffers, D-J., Salas, M., & Munoz-Espin, D. (2013). Phage phi 29 protein p1 promotes replication by associating with the FtsZ ring of the divisome in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America, 110(30), 12313-12318. https://doi.org/10.1073/pnas.1311524110

Lages, M. C. A., Beilharz, K., Angeles, D. M., Veening, J-W., & Scheffers, D-J. (2013). The localization of key Bacillus subtilis penicillin binding proteins during cell growth is determined by substrate availability. Environmental Microbiology, 15(12), 3272-3281. https://doi.org/10.1111/1462-2920.12206

Ali, H., Ries, M. I., Nijland, J. G., Lankhorst, P. P., Hankemeier, T., Bovenberg, R. A. L., Vreeken, R. J., & Driessen, A. J. M. (2013). A Branched Biosynthetic Pathway Is Involved in Production of Roquefortine and Related Compounds in Penicillium chrysogenum. PLoS ONE, 8(6), [e65328]. https://doi.org/10.1371/journal.pone.0065328

Infed, N., Smits, S. H. J., Dittrich, T., Braun, M., Driessen, A. J. M., Hanekop, N., & Schmitt, L. (2013). Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters. Molecular Membrane Biology, 30(2), 217-227. https://doi.org/10.3109/09687688.2012.758876

Lycklama a Nijeholt, J. A., de Keyzer, J., Prabudiansyah, I., & Driessen, A. J. M. (2013). Characterization of the supporting role of SecE in protein translocation. FEBS Letters, 587(18), 3083-3088. https://doi.org/10.1016/j.febslet.2013.07.046

Kedrov, A., Sustarsic, M., de Keyzer, J., Caumanns, J. J., Wu, Z. C., & Driessen, A. J. M. (2013). Elucidating the Native Architecture of the YidC: Ribosome Complex. Journal of Molecular Biology, 425(22), 4112-4124. https://doi.org/10.1016/j.jmb.2013.07.042

van Wolferen, M., Ajon, M., Driessen, A. J. M., & Albers, S-V. (2013). How hyperthermophiles adapt to change their lives: DNA exchange in extreme conditions. Extremophiles, 17(4), 545-563. https://doi.org/10.1007/s00792-013-0552-6

Wu, Z. C., de Keyzer, J., Berrelkamp-Lahpor, G. A., & Driessen, A. J. M. (2013). Interaction of Streptococcus mutans YidC1 and YidC2 with Translating and Nontranslating Ribosomes. Journal of Bacteriology, 195(19), 4545-4551. https://doi.org/10.1128/JB.00792-13

Wolferen, M. V., Ajon, M., Driessen, A. J. M., & Albers, S-V. (2013). Molecular analysis of the UV-inducible pili operon from Sulfolobus acidocaldarius. MicrobiologyOpen, 2(6), 928-937. https://doi.org/10.1002/mbo3.128

Taufik, I., Kedrov, A., Exterkate, M., & Driessen, A. J. M. (2013). Monitoring the Activity of Single Translocons. Journal of Molecular Biology, 425(22), 4145-4153. https://doi.org/10.1016/j.jmb.2013.08.012

Krol, E., van Kessel, S. P., van Bezouwen, L. S., Kumar, N., Boekema, E. J., & Scheffers, D-J. (2012). Bacillus subtilis SepF Binds to the C-Terminus of FtsZ. PLoS ONE, 7(8), [e43293]. https://doi.org/10.1371/journal.pone.0043293

Yu, Z., Bekker, M., Tramonti, A., Cook, G. M., van Ulsen, P., Scheffers, D-J., de Mattos, J. T., De Biase, D., & Luirink, J. (2011). Activators of the Glutamate-Dependent Acid Resistance System Alleviate Deleterious Effects of YidC Depletion in Escherichia coli. Journal of Bacteriology, 193(6), 1308-1316. https://doi.org/10.1128/JB.01209-10

Guendogdu, M. E., Kawai, Y., Pavlendova, N., Ogasawara, N., Errington, J., Scheffers, D-J., Hamoen, L. W., & Gündoğdu, M. E. (2011). Large ring polymers align FtsZ polymers for normal septum formation. EMBO Journal, 30(3), 617-626. https://doi.org/10.1038/emboj.2010.345

Fernandes de Oliveira, I. F., Sousa Borges, A. D., Kooij, V., Bartosiak-Jentys, J., Luirink, J., & Scheffers, D-J. (2010). Characterization of ftsZ Mutations that Render Bacillus subtilis Resistant to MinC. PLoS ONE, 5(8), [e12048]. https://doi.org/10.1371/journal.pone.0012048

Ribeiro, J. P., Palczewska, M., André, S., Cañada, F. J., Gabius, H-J., Jiménez-Barbero, J., Mellström, B., Naranjo, J. R., Scheffers, D-J., & Groves, P. (2010). Diffusion nuclear magnetic resonance spectroscopy detects substoichiometric concentrations of small molecules in protein samples. Analytical Biochemistry, 396(1), 117-123. https://doi.org/10.1016/j.ab.2009.09.001

Pop, O. I., Soprova, Z., Koningstein, G., Scheffers, D-J., Ulsen, P. V., Wickström, D., Gier, J-W. D., & Luirink, J. (2009). YidC is required for the assembly of the MscL homopentameric pore. The FEBS Journal, 276(17), 4891-4899. https://doi.org/10.1111/j.1742-4658.2009.07188.x

Formstone, A., Carballido-López, R., Noirot, P., Errington, J., & Scheffers, D-J. (2008). Localization and Interactions of Teichoic Acid Synthetic Enzymes in Bacillus subtilis. Journal of Bacteriology, 190(5), 1812-1821. https://doi.org/10.1128/JB.01394-07

Scheffers, D-J. (2008). The effect of MinC on FtsZ polymerization is pH dependent and can be counteracted by ZapA. FEBS Letters, 582(17), 2601-2608. https://doi.org/10.1016/j.febslet.2008.06.038

Scheffers, D-J. (2007). Cell wall growth during elongation and division: one ring to bind them? Molecular Microbiology, 64(4), 877-880. https://doi.org/10.1111/j.1365-2958.2007.05731.x

Scheffers, D-J., Robichon, C., Haan, G. J., Blaauwen, T. D., Koningstein, G., Bloois, E. V., Beckwith, J., & Luirink, J. (2007). Contribution of the FtsQ Transmembrane Segment to Localization to the Cell Division Site. Journal of Bacteriology, 189(20), 7273-7280. https://doi.org/10.1128/JB.00723-07

Scheffers, D-J., & Pinho, M. G. (2005). Bacterial Cell Wall Synthesis: New Insights from Localization Studies. Microbiology and Molecular Biology Reviews, 69(4), 585-607. https://doi.org/10.1128/MMBR.69.4.585-607.2005

Scheffers, D-J. (2005). Dynamic localization of penicillin-binding proteins during spore development in Bacillus subtilis. Microbiology, 151(3), 999-1012. https://doi.org/10.1099/mic.0.27692-0

Scheffers, D-J., & Errington, J. (2004). PBP1 Is a Component of the Bacillus subtilis Cell Division Machinery. Journal of Bacteriology, 186(15), 5153-5156. https://doi.org/10.1128/JB.186.15.5153-5156.2004

Koppelman, CM., Aarsman, MEG., Postmus, J., Pas, E., Muijsers, AO., Scheffers, DJ., Nanninga, N., & den Blaauwen, T. (2004). R174 of Escherichia coli FtsZ is involved in membrane interaction and protofilament bundling, and is essential for cell division. Molecular Microbiology, 51(3), 645-657. https://doi.org/10.1046/j.1365-2958.2003.03876.x

Scheffers, D-J., Jones, L. J. F., & Errington, J. (2004). Several distinct localization patterns for penicillin-binding proteins in Bacillus subtilis. Molecular Microbiology, 51(3), 749-764.

Errington, J., Daniel, R. A., & Scheffers, D-J. (2003). Cytokinesis in Bacteria. Microbiology and Molecular Biology Reviews, 67(1), 52-65. https://doi.org/10.1128/MMBR.67.1.52-65.2003

Scheffers, D-J., de Wit, J. G., Blaauwen, T. D., & Driessen, A. J. M. (2002). GTP hydrolysis of cell division protein FtsZ: Evidence that the active site is formed by the association of monomers: Evidence that the Active Site Is Formed by the Association of Monomers. Biochemistry, 41(2), 521 - 529. https://doi.org/10.1021/bi011370i

Scheffers, D-J., & Driessen, A. J. M. (2002). Immediate GTP hydrolysis upon FtsZ polymerization. Molecular Microbiology, 43(6), 1517 - 1521. https://doi.org/10.1046/j.1365-2958.2002.02828.x

Scheffers, D-J., de Wit, J. G., Blaauwen, T. D., & Driessen, A. J. M. (2001). Substitution of a conserved aspartate allows cation-induced polymerization of FtsZ. FEBS Letters, 494(1-2), 34 - 37. https://doi.org/10.1016/S0014-5793(01)02310-9

Scheffers, D-J., & Driessen, A. J. M. (2001). The polymerization mechanism of the bacterial cell division protein FtsZ. FEBS Letters, 506(1), 6 - 10. https://doi.org/10.1016/S0014-5793(01)02855-1

Scheffers, D. J., den Blaauwen, T., & Driessen, A. J. (2000). Non-hydrolysable GTP-gamma-S stabilizes the FtsZ polymer in a GDP-bound state. Molecular Microbiology, 35(5), 1211-1219. https://doi.org/10.1046/j.1365-2958.2000.01791.x