Research lines

• Genetics of complex immune-related diseases including projects with Organs-on-Chips, Pro-Seq
• Gut-on-chip

Sasha Zhernakova
Sebo Withoff
Vinod Kumar
Iris Jonkers
Cisca Wijmenga

• Big data approaches to identifying environmental risk factors for disease
• Factor analytic modeling of expression data and EQTL mapping
• Using systems genetics to understand complex biological systems by integrating systems biology with genetics
• Systems genetics of celiac disease, with a focus on non-coding regions of the genome
• Integration of high-throughput expression and sequence data into the Oncology workstation (CTMM project)

See also the website of MOLGENIS

Morris Swertz
Lude Franke
Jingyuan Fu

Cleo van Diemen
Rolf Sijmons

Chromosome 6 research (a parent-driven project)
CHARGE syndrome
Phelan-McDermid syndrome (22q13 deletion syndrome)

EUROCAT - Epidemiological Surveillance of Congenital Anomalies
Eurolinkcat - establishing a linked European cohort of children with congenital anomalies

Clinical Genetics of Familial Cancer

Rolf Sijmons, Helga Westers, Klaas Kok

Renal Cell Cancer

Klaas Kok, Eva van den Berg

FaCD (Familial Cancer Database)

Rolf Sijmons

SpinoCerebellar Ataxia (SCA)

Genetic screening in children with epilepsy

The ELSI research programme aims to provide the evidence base for offering clinical genetic services to patients using new techniques and innovations more