Skip to ContentSkip to Navigation
OnderzoekGBBMolecular GeneticsVeening-lab (MolGen)

Publications

2017

Liu, X., Li, J-W., Feng, Z., Luo, Y., Veening, J-W., & Zhang, J-R. (2017). Transcriptional Repressor PtvR Regulates Phenotypic Tolerance to Vancomycin in Streptococcus pneumoniae. Journal of Bacteriology. DOI: 10.1128/JB.00054-17
Morales Angeles, D., Liu, Y., Hartman, A. M., Borisova, M., de Sousa Borges, A., de Kok, N., ... Scheffers, D-J. (2017). Pentapeptide-rich peptidoglycan at the Bacillus subtilis cell-division site. Molecular Microbiology, 104(2), 319-333. DOI: 10.1111/mmi.13629
Hassane, M., Demon, D., Soulard, D., Fontaine, J., Keller, L. E., Patin, E. C., ... Paget, C. (2017). Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections. Mucosal immunology. DOI: 10.1038/mi.2016.113
Dockerty, P., Edens, J. G., Tol, M. B., Morales Angeles, D., Domenech Pena, A., Liu, Y., ... Witte, M. D. (2017). Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins. Organic & Biomolecular Chemistry, 15(4), 894-910. DOI: 10.1039/c6ob01664b
Liu, X., Gallay, C., Kjos, M., Domenech, A., Slager, J., van Kessel, S. P., ... Veening, J-W. (2017). High-throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae. Molecular Systems Biology, 13(5), 1-18. [931]. DOI: 10.15252/msb.20167449

2016

Sorg, R. A., Lin, L., van Doorn, G. S., Sorg, M., Olson, J., Nizet, V., & Veening, J-W. (2016). Collective resistance in microbial communities by intracellular antibiotic deactivation. PLOS BIOLOGY, 14(12), [e2000631]. DOI: 10.1371/journal.pbio.2000631
Slager, J., & Veening, J-W. (2016). Hard-Wired Control of Bacterial Processes by Chromosomal Gene Location. Trends in Microbiology, 24(10), 788-800. [TIMI 1345]. DOI: 10.1016/j.tim.2016.06.003
Aprianto, R., Slager, J., Holsappel, S., & Veening, J-W. (2016). Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during early infection. Genome Biology, 17(1), 1-16. [198]. DOI: 10.1186/s13059-016-1054-5
Kuipers, K., Gallay, C., Martinek, V., Rohde, M., Martinkova, M., van der Beek, S. L., ... de Jonge, M. I. (2016). Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae. Molecular Microbiology, 101(1), 12-26. DOI: 10.1111/mmi.13312
Kjos, M., Miller, E., Slager, J., Lake, F. B., Gericke, O., Roberts, I. S., ... Veening, J-W. (2016). Expression of Streptococcus pneumoniae Bacteriocins Is Induced by Antibiotics via Regulatory Interplay with the Competence System. PLoS Pathogens, 12(2), e1005422. DOI: 10.1371/journal.ppat.1005422
Oppegård, C., Kjos, M., Veening, J-W., Nissen-Meyer, J., & Kristensen, T. (2016). A putative amino acid transporter determines sensitivity to the two-peptide bacteriocin plantaricin JK. MicrobiologyOpen, 5(4), 700-708. DOI: 10.1002/mbo3.363
Jim, K. K., Engelen-Lee, J., van der Sar, A. M., Bitter, W., Brouwer, M. C., van der Ende, A., ... Vandenbroucke-Grauls, C. M. J. E. (2016). Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model. Journal of neuroinflammation, 13(1), 1-13. [(2016) 13:188]. DOI: 10.1186/s12974-016-0655-y

2015

Sorg, R. A., & Veening, J-W. (2015). Microscale insights into pneumococcal antibiotic mutant selection windows. Nature Communications, 6(8773), 8773. [9773]. DOI: 10.1038/ncomms9773
Nourikyan, J., Kjos, M., Mercy, C., Cluzel, C., Morlot, C., Noirot-Gros, M-F., ... Grangeasse, C. (2015). Autophosphorylation of the Bacterial Tyrosine-Kinase CpsD Connects Capsule Synthesis with the Cell Cycle in Streptococcus pneumoniae. PLoS genetics, 11(9), 1-29. [e1005518]. DOI: 10.1371/journal.pgen.1005518
Beilharz, K., van Raaphorst, R., Kjos, M., & Veening, J-W. (2015). Red fluorescent proteins for gene expression and protein localization studies in Streptococcus pneumoniae and efficient transformation with Gibson assembled DNA. Applied and environmental microbiology, 81, 7244-7252. [AEM.02033-15]. DOI: 10.1128/AEM.02033-15
Detert Oude Weme, R. G. J., Kovács, Á. T., de Jong, S. J. G., Veening, J-W., Siebring, J., & Kuipers, O. P. (2015). Single Cell FRET Analysis for the Identification of Optimal FRET-Pairs in Bacillus subtilis Using a Prototype MEM-FLIM System. Plos one, 10(4), e0123239. DOI: 10.1371/journal.pone.0123239
Sorg, R. A., Kuipers, O. P., & Veening, J-W. (2015). Gene Expression Platform for Synthetic Biology in the Human Pathogen Streptococcus pneumoniae. ACS Synthetic Biology, 4(3), 228-39. DOI: 10.1021/sb500229s
Kjos, M., Aprianto, R., Fernandes, V. E., Andrew, P. W., van Strijp, J. A. G., Nijland, R., & Veening, J-W. (2015). Bright fluorescent Streptococcus pneumoniae for live cell imaging of host-pathogen interactions. Journal of Bacteriology. DOI: 10.1128/JB.02221-14
Veening, J-W. (2015). To mutate or not to mutate: Genetic and epigenetic heterogeneity contribute to bacterial adaptation (comment on DOI 10.1002/bies.201400153). BioEssays. DOI: 10.1002/bies.201400192
Paixão, L., Oliveira, J., Veríssimo, A., Vinga, S., Lourenço, E. C., Ventura, M. R., ... Neves, A. R. (2015). Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and Infection. PLoS ONE, 10(3), e0121042. DOI: 10.1371/journal.pone.0121042
Attaiech, L., Minnen, A., Kjos, M., Gruber, S., & Veening, J-W. (2015). The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae. Mbio, 6(4), 1-8. DOI: 10.1128/mBio.00662-15

2014

Daszczuk, A., Dessalegne, Y., Drenth, I., Hendriks, E., Jo, E., van Lente, T., ... Veening, J-W. (2014). Bacillus subtilis Biosensor Engineered To Assess Meat Spoilage. ACS Synthetic Biology, 3(12), 999-1002. DOI: 10.1021/sb5000252
Yuzenkova, Y., Gamba, P., Herber, M., Attaiech, L., Shafeeq, S., Kuipers, O. P., ... Veening, J-W. (2014). Control of transcription elongation by GreA determines rate of gene expression in Streptococcus pneumoniae. Nucleic Acids Research, 42(17), 10987-10999. DOI: 10.1093/nar/gku790
Kjos, M., Oppegård, C., Diep, D. B., Nes, I. F., Veening, J-W., Nissen-Meyer, J., & Kristensen, T. (2014). Sensitivity to the two-peptide bacteriocin lactococcin G is dependent on UppP, an enzyme involved in cell-wall synthesis. Molecular Microbiology, 92(6), 1177-87. DOI: 10.1111/mmi.12632
Peters, K., Schweizer, I., Beilharz, K., Stahlmann, C., Veening, J-W., Hakenbeck, R., & Denapaite, D. (2014). Streptococcus pneumoniae PBP2x mid-cell localization requires the C-terminal PASTA domains and is essential for cell shape maintenance. Molecular Microbiology, 92(4), 733-55. DOI: 10.1111/mmi.12588
Slager, J., Kjos, M., Attaiech, L., & Veening, J-W. (2014). Antibiotic-induced replication stress triggers bacterial competence by increasing gene dosage near the origin. Cell, 157(2), 395-406. DOI: 10.1016/j.cell.2014.01.068
Kjos, M., & Veening, J-W. (2014). Tracking of chromosome dynamics in live Streptococcus pneumoniae reveals that transcription promotes chromosome segregation. Molecular Microbiology, 91(6), 1088-105. DOI: 10.1111/mmi.12517
Gruber, S., Veening, J-W., Bach, J., Blettinger, M., Bramkamp, M., & Errington, J. (2014). Interlinked Sister Chromosomes Arise in the Absence of Condensin during Fast Replication in B. subtilis. Current Biology, 24(3), 293-298. DOI: 10.1016/j.cub.2013.12.049
Bhogale, P. M., Sorg, R. A., Veening, J-W., & Berg, J. (2014). What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems. Nucleic Acids Research, 42(18), 11321-11328. DOI: 10.1093/nar/gku839

2013

Trip, E. N., Veening, J-W., Stewart, E. J., Errington, J., & Scheffers, D-J. (2013). Balanced transcription of cell division genes in Bacillus subtilis as revealed by single cell analysis. Environmental Microbiology, 15(12), 3196-3209. DOI: 10.1111/1462-2920.12148
Lages, M. C. A., Beilharz, K., Angeles, D. M., Veening, J-W., & Scheffers, D-J. (2013). The localization of key Bacillus subtilis penicillin binding proteins during cell growth is determined by substrate availability. Environmental Microbiology, 15(12), 3272-3281. DOI: 10.1111/1462-2920.12206
Overkamp, W., Beilharz, K., Weme, R. D. O., Solopova, A., Karsens, H., Kovacs, A. T., ... Veening, J-W. (2013). Benchmarking Various Green Fluorescent Protein Variants in Bacillus subtilis, Streptococcus pneumoniae, and Lactococcus lactis for Live Cell Imaging. Applied and Environmental Microbiology, 79(20), 6481-6490. DOI: 10.1128/AEM.02033-13
Pinho, M. G., Kjos, M., & Veening, J-W. (2013). How to get (a)round: mechanisms controlling growth and division of coccoid bacteria. Nature Reviews Microbiology, 11(9), 601-614. DOI: 10.1038/nrmicro3088
Burghout, P., Quintero, B., Bos, L., Beilharz, K., Veening, J-W., de Jonge, M. I., ... Hermans, P. W. M. (2013). A single amino acid substitution in the MurF UDP-MurNAc-pentapeptide synthetase renders Streptococcus pneumoniae dependent on CO2 and temperature. Molecular Microbiology, 89(3), 494-506. DOI: 10.1111/mmi.12292
Kjos, M., & Veening, J. -W. (2013). Transcription contributes to efficient chromosome segregation in Streptococcus pneumoniae. Febs Journal, 280, 6-6.
Boonstra, M., de Jong, I. G., Scholefield, G., Murray, H., Kuipers, O. P., & Veening, J-W. (2013). Spo0A regulates chromosome copy number during sporulation by directly binding to the origin of replication in Bacillus subtilis. Molecular Microbiology, 87(4), 925-938. DOI: 10.1111/mmi.12141
Jørgensen, M. G., Raaphorst, R. V., & Veening, J-W. (2013). Noise and Stochasticity in Gene Expression: A Pathogenic Fate Determinant. In C. Harwood, & A. Wipat (Eds.), Microbial Synthetic Biology (40 ed., pp. 157-175). (Methods in Microbiology; No. 40). Oxford, London: s.n..

2012

de Jong, I. G., Veening, J-W., & Kuipers, O. P. (2012). Single cell analysis of gene expression patterns during carbon starvation in Bacillus subtilis reveals large phenotypic variation. Environmental Microbiology, 14(12), 3110-3121. DOI: 10.1111/j.1462-2920.2012.02892.x
Beilharz, K., Nováková, L., Fadda, D., Branny, P., Massidda, O., & Veening, J-W. (2012). Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP. Proceedings of the National Academy of Sciences of the United States of America, 109(15), E905-E913. DOI: 10.1073/pnas.1119172109

2011

Minnen, A., Attaiech, L., Thon, M., Gruber, S., & Veening, J-W. (2011). SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae. Molecular Microbiology, 81(3), 676-688. DOI: 10.1111/j.1365-2958.2011.07722.x
Scholefield, G., Veening, J-W., & Murray, H. (2011). DnaA and ORC: more than DNA replication initiators. Trends in Cell Biology, 21(3), 188-194. DOI: 10.1016/j.tcb.2010.10.006
Jong, I. G. D., Beilharz, K., Kuipers, O. P., & Veening, J-W. (2011). Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy. Journal of Visualized Experiments, 6(53), 1-6. DOI: 10.3791/3145

2010

de Jong, I. G., Veening, J-W., & Kuipers, O. P. (2010). Heterochronic Phosphorelay Gene Expression as a Source of Heterogeneity in Bacillus subtilis Spore Formation. Journal of Bacteriology, 192(8), 2053 - 2067. DOI: 10.1128/JB.01484-09
Veening, J-W., & Kuipers, O. P. (2010). Gene position within a long transcript as a determinant for stochastic switching in bacteria. Molecular Microbiology, 76(2), 269-272. DOI: 10.1111/j.1365-2958.2010.07113.x
Nijland, R., Burgess, J. G., Errington, J., & Veening, J-W. (2010). Transformation of Environmental Bacillus subtilis Isolates by Transiently Inducing Genetic Competence. PLoS ONE, 5(3), e9724-1-e9724-7. DOI: 10.1371/journal.pone.0009724

2009

Eberhardt, A., Wu, L. J., Errington, J., Vollmer, W., & Veening, J-W. (2009). Cellular localization of choline-utilization proteins in Streptococcus pneumoniae using novel fluorescent reporter systems. Molecular Microbiology, 74(2), 395-408. DOI: 10.1111/j.1365-2958.2009.06872.x
Gamba, P., Veening, J-W., Saunders, N. J., Hamoen, L. W., & Daniel, R. A. (2009). Two-Step Assembly Dynamics of the Bacillus subtilis Divisome. Journal of Bacteriology, 191(13), 4186-4194. DOI: 10.1128/JB.01758-08
Veening, J-W., Murray, H., & Errington, J. (2009). A mechanism for cell cycle regulation of sporulation initiation in Bacillus subtilis. Genes & Development, 23(16), 1959-1970. DOI: 10.1101/gad.528209

2008

Veening, J-W., Igoshin, O. A., Eijlander, R. T., Nijland, R., Hamoen, L. W., & Kuipers, O. P. (2008). Transient heterogeneity in extracellular protease production by Bacillus subtilis. Molecular Systems Biology, 4(6), 184 - 184. [184]. DOI: 10.1038/msb.2008.18
Veening, J-W., Stewart, E. J., Berngruber, T. W., Taddei, F., Kuipers, O. P., & Hamoen, L. W. (2008). Bet-hedging and epigenetic inheritance in bacterial cell development. Proceedings of the National Academy of Sciences of the United States of America, 105(11), 4393-4398. DOI: 10.1073/pnas.0700463105
Smits, W. K., Veening, J-W., & Kuipers, O. P. (2008). Phenotypic Variation and Bistable Switching in Bacteria. In W. El-Sharoud (Ed.), Bacterial Physiology: a Molecular Approach (pp. 339-365). Berlin: Springer Verlag.
Veening, J-W., Smits, W. K., & Kuipers, O. P. (2008). Bistability, Epigenetics, and Bet-Hedging in Bacteria. Annual Review of Microbiology, 62(1), 193-210. DOI: 10.1146/annurev.micro.62.081307.163002

2007

Lulko, A. T., Veening, J. W., Buist, G., Smits, W. K., Blom, E., Beekman, A. C., ... Kuipers, O. P. (2007). Production and secretion stress caused by overexpression of heterologous alpha-amylase leads to inhibition of sporulation and a prolonged motile phase in Bacillus subtilis. Applied Environmental Microbiology, 73(16), 5354-5362. DOI: 10.1128/AEM.00472-07
Smits, W. K., Bongiorni, C., Veening, J-W., Hamoen, L. W., Kuipers, O. P., & Perego, M. (2007). Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis. Molecular Microbiology, 65(1), 103-120. DOI: 10.1111/j.1365-2958.2007.05776.x
Nijland, R., Veening, J-W., & Kuipers, O. P. (2007). A derepression system based on the Bacillus subtilis sporulation pathway offers dynamic control of heterologous gene expression. Applied and Environmental Microbiology, 73(7), 2390-2393. DOI: 10.1128/AEM.02266-06
Romero, D., de Vicente, A., Rakotoaly, R. H., Dufour, S. E., Veening, J-W., Arrebola, E., ... Stacey, G. (Ed.) (2007). The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca. Molecular Plant-Microbe Interactions, 20(4), 430-440. DOI: 10.1094/MPMI-20-4-0430
Veening, J-W. (2007). Phenotypic variation in Bacillus subtilis: bistability in the sporulation pathway s.n.

2006

Romero, D., Perez-Garcia, A., Veening, J-W., de Vicente, A., Kuipers, O. P., & de, V. A. (2006). Transformation of undomesticated strains of Bacillus subtilis by protoplast electroporation. Journal of microbiological methods, 66(3), 556-559. DOI: 10.1016/j.mimet.2006.01.005
Veening, J. -W., Smits, W. K., Hamoen, L. W., & Kuipers, O. P. (2006). Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media. Journal of Applied Microbiology, 101(3), 531-541. DOI: 10.1111/j.1365-2672.2006.02911.x
Smits, W., Kuipers, O. P., & Veening, J. W. (2006). Phenotypic variation in bacteria: The role of feedback regulation. Nature Reviews Microbiology, 4(4), 259-271. DOI: 10.1038/nrmicro1381
Veening, J. W., Kuipers, O. P., Brul, S., Hellingwerf, K. J., & Kort, R. (2006). Effects of Phosphorelay Perturbations on Architecture, Sporulation, and Spore Resistance in Biofilms of Bacillus subtilis. Journal of Bacteriology, 188(8), 3099-3109. DOI: 10.1128/JB.188.8.3099-3109.2006

2005

Bongers, R. S., Veening, J. W., van Wieringen, M., Kuipers, O. P., & Kleerebezem, M. (2005). Development and characterization of a subtilin-regulated expression system in Bacillus subtilis: Strict control of gene expression by addition of subtilin. Appl.Environ.Microbiol., 71(12), 8818-8824. DOI: 10.1128/AEM.71.12.8818-8824.2005
Veening, J. W., Hamoen, L. W., & Kuipers, O. P. (2005). Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis. Molecular Microbiology, 56(6), 1481-1494. DOI: 10.1111/j.1365-2958.2005.04659.x

2004

Veening, J. W., Smits, W. K., Hamoen, L. W., Jongbloed, J. D. H., Kuipers, O. P., & Smits, W. K. (2004). Visualization of differential gene expression by improved cyan fluorescent protein and yellow fluorescent protein production in Bacillus subtilis. Applied Environmental Microbiology, 70(11), 6809-6815. DOI: 10.1128/AEM.70.11.6809-6815.2004
Westers, H., Darmon, E., Zanen, G., Veening, J-W., Kuipers, O. P., Bron, S., ... Dijl, J. M. V. (2004). The Bacillus secretion stress response is an indicator for α-amylase production levels. Letters in Applied Microbiology, 39(1), 65-73. DOI: 10.1111/j.1472-765X.2004.01539.x

2003

Antelmann, H., Darmon, E., Noone, D., Veening, J. W., Westers, H., Bron, S., ... van Dijl, J. M. (2003). The extracellular proteome of Bacillus subtilis under secretion stress conditions. Molecular Microbiology, 49(1), 143 - 156. DOI: 10.1046/j.1365-2958.2003.03565.x
Laatst gewijzigd:06 september 2015 20:04