Dr. Paulino and Prof. Poolman receive ENW-KLEIN grant
Dr. Cristina Paulino and Prof. Bert Poolman ( GBB ) have received an ENW-KLEIN grant from the Netherlands Organization for Scientific Research (NWO) worth EUR 700,000. The grant is for their project ‘Unravelling the mechanism of action of an osmoregulator’.
One of the outstanding questions in biochemistry and cell biology relates to the control of cell volume of microorganisms during growth and under environmental stress. Cells need to respond rapidly to fluctuating environmental conditions, for example by a prompt and large accumulation of compatible solutes. Conversely, a too high intake of osmolytes would be detrimental for the cell, and requires a fine-tuned regulation mechanism. Yet, the molecular details by which microorganisms control their volume are still largely elusive. Paulino and Poolman aim to elucidate the full mechanism of transport and regulation of the ABC importer OpuA, using cryo-electron microscopy and single-molecule biophysical methods.
ENW-KLEIN
The ENW-KLEIN grant offers researchers the opportunity to establish scientific innovations that can form the basis for research themes of the future.
Last modified: | 24 March 2021 09.13 a.m. |
More news
-
13 May 2024
‘The colourful cells of petals never get boring!’
Most people will enjoy colours in nature. However, the interest of evolutionary biologist Casper van der Kooi goes much further: he studies how flowers, birds, butterflies, and beetles get their colours. He also studies how these colours are used...
-
13 May 2024
Trapping molecules
In his laboratory, physicist Steven Hoekstra is building an experimental set-up made of two parts: one that produces barium fluoride molecules, and a second part that traps the molecules and brings them to an almost complete standstill so they can...
-
07 May 2024
Lecture with soon to be Honorary Doctor Gerrit Hiemstra on May 24
In celebration of his honorary doctorate, FSE has invited Hiemstra to give a lecture entitled ‘Science, let's talk about it’ on the morning of 24 May