PhD ceremony: Mr. G. Malviya, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen
Title: Radiolabelled monoclonal antibodies for molecular imaging of chronic inflammatory diseases
Promotor(s): prof. Signore, prof. R.A.J.O. Dierckx
Faculty: Medical Sciences
This thesis describes the synthesis and application of different radiolabelled monoclonal antibodies (mAbs), including anti-TNF
a
mAb, anti-CD20 mAb, anti-CD3 mAb and anti-HLA-DR mAb. All mAbs were radiolabelled with
99mTc and evaluated for receptor mapping and/or therapy decision making in patients.
