prof. dr. R.P. (Rob) Coppes
Professor

Telephone:
Secretariat:
g.noppert umcg.nl
E-mail:
r.p.coppes umcg.nl
Research
1 - 50 out of 135Page size: 50
- 2020
- Aznar, M. C., Bacchus, C., Coppes, R. P., Deutsch, E., Georg, D., Haustermans, K., Hoskin, P., Krause, M., Lartigau, E. F., Löck, S., Offersen, B., Overgaard, J., I Thwaites, D., van der Kogel, A. J., van der Heide, U. A., Valentini, V., & Baumann, M. (2020). Radiation oncology in the new virtual and digital era. Radiotherapy and Oncology. https://doi.org/10.1016/j.radonc.2020.12.031
- Coppes, R. P. (2020). Macrophages Come To The Rescue. Cancer Research, 80(24), 5462-5463. https://doi.org/10.1158/0008-5472.CAN-20-3499
- Nagle, P. W., & Coppes, R. P. (2020). Current and Future Perspectives of the Use of Organoids in Radiobiology. Cells, 9(12), [2649]. https://doi.org/10.3390/cells9122649
- Beukinga, R. J., Wang, D., Karrenbeld, A., Dijksterhuis, W. P. M., Faber, H., Burgerhof, J. G. M., Mul, V. E. M., Slart, R. H. J. A., Coppes, R. P., & Plukker, J. T. M. (2020). Addition of HER2 and CD44 to F-18-FDG PET-based clinico-radiomic models enhances prediction of neoadjuvant chemoradiotherapy response in esophageal cancer. European Radiology. https://doi.org/10.1007/s00330-020-07439-8
- Steenbakkers, R., Rijn-Dekker, van, I., Stokman, M., Kierkels, R. G. J., Bosch, van den, L., Hoek, van den, A., Bijl, H., Kramer, M., Coppes, R. P., Langendijk, J. A., & Luijk, van, P. (2020). Stem cell sparing radiotherapy for head and neck cancer patients: a double-blind randomized controlled trial. Abstract from annual PhD meeting of the Cancer Research Center Groningen (CRCG), .
- Sondorp, L. H. J., Ogundipe, V. M. L., Groen, A. H., Kelder, W., Kemper, A., Links, T. P., Coppes, R. P., & Kruijff, S. (2020). Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening. Cancers, 12(11), 1-15. [3212]. https://doi.org/10.3390/cancers12113212
- Peng, X., Wu, Y., Brouwer, U., van Vliet, T., Wang, B., Demaria, M., Barazzuol, L., & Coppes, R. P. (2020). Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche. Cell death & disease, 11(10), [854]. https://doi.org/10.1038/s41419-020-03074-9
- 2019
- Du, L., Wang, L., Gan, J., Yao, Z., Lin, W., Li, J., Guo, Y., Chen, Y., Zhou, F., Jim Yeung, S-C., Coppes, R. P., Zhang, D., & Zhang, H. (2019). MTA3 Represses Cancer Stemness by Targeting the SOX2OT/SOX2 Axis. iScience , 22, 353-368. https://doi.org/10.1016/j.isci.2019.11.009
- Vozenin, M-C., Baumann, M., Coppes, R. P., & Bourhis, J. (2019). FLASH radiotherapy International Workshop. Radiotherapy and Oncology, 139, 1-3. https://doi.org/10.1016/j.radonc.2019.07.020
- Steenbakkers, R., Stokman, M. A., Kierkels, R. G. J., Schuurman, M., Hoek, A. V. D., Bijl, H., Kramer, M., Coppes, R. P., Langendijk, J. A., & van Luijk, P. (2019). Stem Cell Sparing IMRT for Head and Neck Cancer Patients: A Double-Blind Randomized Controlled Trial. International Journal of Radiation Oncology Biology Physics, 105(1), S16-S17. https://doi.org/10.1016/j.ijrobp.2019.06.411
- van Berlo, D., Khmelinskii, A., Gasparini, A., Salguero, F. J., Floot, B., de Wit, N., van de Ven, M., Song, J. Y., Coppes, R. P., Verheij, M., Sonke, J. J., & Vens, C. (2019). Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models. Radiotherapy and Oncology, 138, 17-24. https://doi.org/10.1016/j.radonc.2019.05.007
- Yao, Z., Du, L., Xu, M., Li, K., Guo, H., Ye, G., Zhang, D., Coppes, R. P., & Zhang, H. (2019). MTA3-SOX2 Module Regulates Cancer Sternness and Contributes to Clinical Outcomes of Tongue Carcinoma. Frontiers in Oncology, 9, [816]. https://doi.org/10.3389/fonc.2019.00816
- Nagle, P. W., van Goethem, M-J., Kempers, M., Kiewit, H., Knopf, A., Langendijk, J. A., Brandenburg, S., van Luijk, P., & Coppes, R. P. (2019). In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field. Radiotherapy and Oncology, 137, 125-129. https://doi.org/10.1016/j.radonc.2019.04.028
- Wang, D., Nagle, P. W., Wang, H. H., Smit, J. K., Faber, H., Baanstra, M., Karrenbeld, A., Chiu, R. K., Plukker, J. T. M., & Coppes, R. P. (2019). Hedgehog Pathway as a Potential Intervention Target in Esophageal Cancer. Cancers, 11(6), [821]. https://doi.org/10.3390/cancers11060821
- Steenbakkers, R., Stokman, M., Kierkels, R., Schuurman, M., Van den Hoek, A., Bijl, H., Dieters, M., Coppes, R., Langendijk, J., & Van Luijk, P. (2019). Stem cell sparing IMRT for head and neck cancer patients: a double-blind randomized controlled trial. Radiotherapy and Oncology, 133, S335-S336. https://doi.org/10.1016/S0167-8140(19)31051-5
- Pringle, S., Wang, X., Verstappen, G. M. P. J., Terpstra, J. H., Zhang, C. K., He, A., Patel, V., Jones, R. E., Baird, D. M., Spijkervet, F. K. L., Vissink, A., Bootsma, H., Coppes, R. P., & Kroese, F. G. M. (2019). Salivary Gland Stem Cells Age Prematurely in Primary Sjogren's Syndrome. Arthritis & Rheumatology, 71(1), 133-142. https://doi.org/10.1002/art.40659
- 2018
- Nagle, P. W., Hosper, N. A., Barazzuol, L., Jellema, A. L., Baanstra, M., van Goethem, M-J., Brandenburg, S., Giesen, U., Langendijk, J. A., van Luijk, P., & Coppes, R. P. (2018). Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction. Clinical Cancer Research, 24(24), 6583-6593. https://doi.org/10.1158/1078-0432.CCR-18-0533
- Peng, X., Varendi, K., Maimets, M., Andressoo, J. O., & Coppes, R. P. (2018). Role of GDNF in the modulation of SGSCs radiation response; regeneration or senescence? Radiotherapy and Oncology, 127, S304. https://doi.org/10.1016/S0167-8140(18)30892-2
- van Luijk, P., & Coppes, R. (2018). Preclinical Radiobiological insights to inform modelling of radiotherapy outcome. In I. El Naqa (Ed.), A Guide to Outcome Modeling In Radiotherapy and Oncology: Listening to the Data (1st ed., pp. 47-52). (Series in Medical Physics and Biomedical Engineering). CRC Press, Taylor and Francis Group. https://doi.org/10.1201/9780429452659
- Mauthe, M., Orhon, I., Rocchi, C., Zhou, X., Luhr, M., Hijlkema, K-J., Coppes, R. P., Engedal, N., Mari, M., & Reggiori, F. (2018). Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion. Autophagy, 14(8), 1435-1455. https://doi.org/10.1080/15548627.2018.1474314
- 2017
- Peng, X., Varendi, K., Maimets, M., Andressoo, J-O., & Coppes, R. P. (2017). Role of glial-cell-derived neurotrophic factor in salivary gland stem cell response to irradiation. Radiotherapy and Oncology, 124(3), 448-454. https://doi.org/10.1016/j.radonc.2017.07.008
- Coppes, R. P., & Dubrovska, A. (2017). Targeting Stem Cells in Radiation Oncology. Clinical Oncology, 29(6), 329-334. https://doi.org/10.1016/j.clon.2017.03.005
- 2016
- Klein Hesselink, E., Brouwers, A. H., Jong, de, J. R., van der Horst-Schrivers, A. N. A., Coppes, R. P., Lefrandt, J. D., Jager, P. L., Vissink, A., & Links, T. P. (2016). Effects of Radioiodine Treatment on Salivary Gland Function in Patients with Differentiated Thyroid Carcinoma: A Prospective Study. Journal of Nuclear Medicine, 57(11), 1685-1691. https://doi.org/10.2967/jnumed.115.169888
- Nagle, P. W., Hosper, N. A., Ploeg, E. M., van Goethem, M-J., Brandenburg, S., Langendijk, J. A., Chiu, R. K., & Coppes, R. P. (2016). The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers. International Journal of Radiation Oncology Biology Physics, 95(1), 103-111. https://doi.org/10.1016/j.ijrobp.2016.02.020
- Pringle, S., Maimets, M., van der Zwaag, M., Stokman, M. A., van Gosliga, D., Zwart, E., Witjes, M. J. H., de Haan, G., van Os, R., & Coppes, R. P. (2016). Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands. STEM CELLS, 34(3), 640-652. https://doi.org/10.1002/stem.2278
- Maimets, M., Rocchi, C., Bron, R., Pringle, S., Kuipers, J., Giepmans, B. N. G., Vries, R. G. J., Clevers, H., de Haan, G., van Os, R., & Coppes, R. P. (2016). Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals. Stem Cell Reports, 6(1), 150-162. https://doi.org/10.1016/j.stemcr.2015.11.009
- van der Veen, S. J., Faber, H., Ghobadi, G., Brandenburg, S., Langendijk, J. A., Coppes, R. P., & van Luijk, P. (2016). Decreasing Irradiated Rat Lung Volume Changes Dose-Limiting Toxicity From Early to Late Effects. International Journal of Radiation Oncology Biology Physics, 94(1), 163-171. https://doi.org/10.1016/j.ijrobp.2015.09.034
- 2015
- Ghobadi, G., Wiegman, E. M., Langendijk, J. A., Widder, J., Coppes, R. P., & van Luijk, P. (2015). A new CT-based method to quantify radiation-induced lung damage in patients. Radiotherapy and Oncology, 117(1), 4-8. https://doi.org/10.1016/j.radonc.2015.07.017
- van Luijk, P., Pringle, S., Deasy, J. O., Moiseenko, V. V., Faber, H., Hovan, A., Baanstra, M., van der Laan, H. P., Kierkels, R. G. J., van der Schaaf, A., Witjes, M. J., Schippers, J. M., Brandenburg, S., Langendijk, J. A., Wu, J., & Coppes, R. P. (2015). Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer. Science Translational Medicine, 7(305), [305ra147]. https://doi.org/10.1126/scitranslmed.aac4441
- van der Veen, S. J., Ghobadi, G., de Boer, R. A., Faber, H., Cannon, M. V., Nagle, P. W., Brandenburg, S., Langendijk, J. A., van Luijk, P., & Coppes, R. P. (2015). ACE inhibition attenuates radiation-induced cardiopulmonary damage. Radiotherapy and Oncology, 114(1), 96-103. https://doi.org/10.1016/j.radonc.2014.11.017
- Nagle, P., Hosper, N., Ploeg, E., van Goethem, M-J., Langendijk, H., Chiu, R., & Coppes, R. (2015). The response of three-dimensional spheroids to particle radiotherapy. Abstract from Annual NVRB Spring Meeting , Utrecht, Netherlands.
- 2014
- Nanduri, L. S. Y., Baanstra, M., Faber, H., Rocchi, C., Zwart, E., de Haan, G., van Os, R., & Coppes, R. P. (2014). Purification and Ex Vivo Expansion of Fully Functional Salivary Gland Stem Cells. Stem Cell Reports, 3(6), 957-964. https://doi.org/10.1016/j.stemcr.2014.09.015
- de Cortie, K., Russell, N. S., Coppes, R. P., Stewart, F. A., & Scharpfenecker, M. (2014). Bone marrow-derived macrophages incorporate into the endothelium and influence vascular and renal function after irradiation. International Journal of Radiation Biology, 90(9), 769-777. https://doi.org/10.3109/09553002.2014.920967
- Benderitter, M., Caviggioli, F., Chapel, A., Coppes, R. P., Guha, C., Klinger, M., Malard, O., Stewart, F., Tamarat, R., Van Luijk, P., & Limoli, C. L. (2014). Stem Cell Therapies for the Treatment of Radiation-Induced Normal Tissue Side Effects. Antioxidants & Redox Signaling, 21(2), 338-355. https://doi.org/10.1089/ars.2013.5652
- Scharpfenecker, M., Floot, B., Russell, N. S., Coppes, R. P., & Stewart, F. A. (2014). Thalidomide Ameliorates Inflammation and Vascular Injury but Aggravates Tubular Damage in the Irradiated Mouse Kidney. International Journal of Radiation Oncology Biology Physics, 89(3), 599-606. https://doi.org/10.1016/j.ijrobp.2014.03.039
- Nagle, P., van Goethem, M-J., van Luijk, P., Langendijk, J. A., Coppes, R., & Chiu, R. (2014). Targeting DNA repair to enhance particle radiotherapy treatment. Abstract from 40th Annual meeting of the European Radiation Research Society, Rhodes, Greece.
ID: 60596