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R.I. Seinstra

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  1. 2020
  2. Koopman, M., Peter, Q., Seinstra, R. I., Perni, M., Vendruscolo, M., Dobson, C. M., Knowles, T. P. J., & Nollen, E. A. A. (2020). Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform. Nature protocols, 15(6), 2071-2106. https://doi.org/10.1038/s41596-020-0321-9
  3. 2019
  4. Janssens, G. E., Lin, X-X., Millan-Ariño, L., Kavšek, A., Sen, I., Seinstra, R. I., Stroustrup, N., Nollen, E. A. A., & Riedel, C. G. (2019). Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging. Cell reports, 27(2), 467-480.e6. https://doi.org/10.1016/j.celrep.2019.03.044
  5. Koopman, M., Seinstra, R. I., & Nollen, E. A. A. (2019). C. elegans as a Model for Synucleinopathies and Other Neurodegenerative Diseases: Tools and Techniques. In T. Bartels (Ed.), Alpha-Synuclein (pp. 93-112). (Methods in Molecular Biology). https://doi.org/10.1007/978-1-4939-9124-2_9
  6. 2018
  7. Mata-Cabana, A., Sin, O., Seinstra, R. I., & Nollen, E. A. A. (2018). Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans. JMIR research protocols, 8(20), [3053]. https://doi.org/10.21769/BioProtoc.3053
  8. Sin, O., Mata-Cabana, A., Seinstra, R. I., & Nollen, E. A. A. (2018). Filter Retardation Assay for Detecting and Quantifying Polyglutamine Aggregates Using Lysates. JMIR research protocols, 8(19), [3042]. https://doi.org/10.21769/BioProtoc.3042
  9. 2017
  10. Sin, O., de Jong, T., Mata-Cabana, A., Kudron, M., Zaini, M. A., Aprile, F. A., Seinstra, R. I., Stroo, E., Prins, R. W., Martineau, C. N., Wang, H. H., Hogewerf, W., Steinhof, A., Wanker, E. E., Vendruscolo, M., Calkhoven, C. F., Reinke, V., Guryev, V., & Nollen, E. A. A. (2017). Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation. Molecular Cell, 65(6), 1096-1108. https://doi.org/10.1016/j.molcel.2017.02.022
  11. Jansen, I. E., Ye, H., Heetveld, S., Lechler, M. C., Michels, H., Seinstra, R. I., Lubbe, S. J., Drouet, V., Lesage, S., Majounie, E., Gibbs, J. R., Nalls, M. A., Ryten, M., Botia, J. A., Vandrovcova, J., Simon-Sanchez, J., Castillo-Lizardo, M., Rizzu, P., Blauwendraat, C., ... International Parkinson’s Disease Genetics Consortium (IPGDC) (2017). Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biology, 18(22). https://doi.org/10.1186/s13059-017-1147-9
  12. 2016
  13. Michels, H., Seinstra, R. I., Uitdehaag, J. C. M., Koopman, M., van Faassen, M., Martineau, C. N., Kema, I. P., Buijsman, R., & Nollen, E. A. A. (2016). Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase. Scientific Reports, 6, [39199]. https://doi.org/10.1038/srep39199
  14. 2013
  15. Krajewska, M., Heijink, A. M., Bisselink, Y. J. W. M., Seinstra, R. I., Sillje, H. H. W., de Vries, E. G. E., & van Vugt, M. A. T. M. (2013). Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination. ONCOGENE, 32(24), 3001-3008. https://doi.org/10.1038/onc.2012.296
  16. 2012
  17. van der Goot, A. T., Zhu, W., Vazquez-Manrique, R. P., Seinstra, R. I., Dettmer, K., Michels, H., Farina, F., Krijnen, J., Melki, R., Buijsman, R. C., Silva, M. R., Thijssen, K. L., Kema, I. P., Neri, C., Oefner, P. J., & Nollen, E. A. A. (2012). Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation. Proceedings of the National Academy of Sciences of the United States of America, 109(37), 14912-14917. https://doi.org/10.1073/pnas.1203083109

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