dr. M. (Marco) Demaria


  1. 2019
  2. Palmer, A. K., Xu, M., Zhu, Y., Pirtskhalava, T., Weivoda, M. M., Hachfeld, C. M., ... Kirkland, J. L. (2019). Targeting senescent cells alleviates obesity-induced metabolic dysfunction. Aging Cell, 18(3), [12950]. https://doi.org/10.1111/acel.12950
  3. Palacio, L., Goyer, M-L., Maggiorani, D., Espinosa, A., Villeneuve, N., Bourbonnais, S., ... Beauséjour, C. (2019). Restored immune cell functions upon clearance of senescence in the irradiated splenic environment. Aging Cell, [e12971]. https://doi.org/10.1111/acel.12971
  4. Calcinotto, A., Kohli, J., Zagato, E., Pellegrini, L., Demaria, M., & Alimonti, A. (2019). Cellular Senescence: Aging, Cancer, and Injury. Physiological reviews, 99(2), 1047-1078. https://doi.org/10.1152/physrev.00020.2018
  5. 2018
  6. Demaria, M. (2018). Biomarkers for cellular senescence. (Patent No. WO2018164580).
  7. Alimirah, F., Valdovinos, A., Chang, E., Alptekin, S., Pulido, T., Jones, E., ... Campisi, J. (2018). Cellular senescence drives skin carcinogenesis. Cancer Research, 78(13). https://doi.org/10.1158/1538-7445.AM2018-466
  8. 2017
  9. Campisi, J., van Deursen, J. M. A., Kirkland, J. L., Tchkonia, T., Baker, D. J., & Demaria, M. (2017). Animal models for cancer and uses thereof. (Patent No. US20170042129).
  10. van Deursen, J. M. A., Baker, D. J., Kirkland, J. L., Tchkonia, T., Campisi, J., Demaria, M., & Laberge, R-M. (2017). Animal models of age-related disorders and age-sensitive traits associated with senescence-inducing stimuli and uses thereof. (Patent No. US2017027139).
  11. Demaria, M., O'Leary, M. N., Chang, J., Shao, L., Liu, S., Alimirah, F., ... Campisi, J. (2017). Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse. Cancer discovery, 7(2), 165-176. https://doi.org/10.1158/2159-8290.CD-16-0241
  12. Laberge, R-M., Campisi, J., Davalos, A., Lopez-Dominguez , J. A., Demaria, M., David, N., ... Zhu, Y. (2017). Compositions and methods for treating senescence-associated diseases and disorders. (Patent No. WO2017008060).
  13. Demaria, M. (2017). Cellular Senescence and Tumor Promotion. In M. Extermann (Ed.), Geriatric Oncology (pp. 1-15). Springer. https://doi.org/10.1007/978-3-319-44870-1_79-1
  14. 2016
  15. Chinta, S. J., Woods, G., Demaria, M., Campisi, J., & Andersen, J. K. (2016). Cellular senescence induced by paraquat drives neuropathology associated with Parkinson's disease. Movement Disorders, 31, S252-S252. [776].
  16. 2015
  17. Kang, C., Xu, Q., Martin, T. D., Li, M. Z., Demaria, M., Aron, L., ... Elledge, S. J. (2015). The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. Science, 349(6255), aaa5612. https://doi.org/10.1126/science.aaa5612
  18. Chinta, S. J., Woods, G., Rane, A., Demaria, M., Campisi, J., & Andersen, J. K. (2015). Cellular senescence and the aging brain. Experimental Gerontology, 68, 3-7. https://doi.org/10.1016/j.exger.2014.09.018
  19. Laberge, R-M., Orjalo, A. V., Patil, C. K., Freund, A., Zhou, L., Curran, S. C., ... Campisi, J. (2015). MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nature Cell Biology, 17(8), 1049-61. https://doi.org/10.1038/ncb3195
  20. Christy, B., Demaria, M., Campisi, J., Huang, J., Jones, D., Dodds, S. G., ... Hasty, P. (2015). p53 and rapamycin are additive. Oncotarget, 6(18), 15802-13. https://doi.org/10.18632/oncotarget.4602
  21. 2014
  22. Demaria, M., Ohtani, N., Youssef, S. A., Rodier, F., Toussaint, W., Mitchell, J. R., ... Campisi, J. (2014). An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Developmental Cell, 31(6), 722-33. https://doi.org/10.1016/j.devcel.2014.11.012
  23. Chinta, S. J., Wood, G., Lieu, C., Rane, A., DeMaria, M., Campisi, J., & Andersen, J. K. (2014). CELLULAR SENESCENCE AND BRAIN AGING. Free Radical Biology and Medicine, 76(1), S3-S3. https://doi.org/10.1016/j.freeradbiomed.2014.10.013
  24. Camporeale, A., Demaria, M., Monteleone, E., Giorgi, C., Wieckowski, M. R., Pinton, P., & Poli, V. (2014). STAT3 Activities and Energy Metabolism: Dangerous Liaisons. Cancers, 6(3), 1579-96. https://doi.org/10.3390/cancers6031579
  25. 2013
  26. Laberge, R-M., Adler, D., DeMaria, M., Mechtouf, N., Teachenor, R., Cardin, G. B., ... Rodier, F. (2013). Mitochondrial DNA damage induces apoptosis in senescent cells. Cell death & disease, 4, [e727]. https://doi.org/10.1038/cddis.2013.199
  27. 2012
  28. Laberge, R-M., Zhou, L., Sarantos, M. R., Rodier, F., Freund, A., de Keizer, P. L. J., ... Campisi, J. (2012). Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell, 11(4), 569-78. https://doi.org/10.1111/j.1474-9726.2012.00818.x
  29. Haines, B., Demaria, M., Mao, X., Xie, L., Campisi, J., Jin, K., & Greenberg, D. A. (2012). Hypoxia-inducible factor-1 and neuroglobin expression. Neuroscience Letters, 514(2), 137-40. https://doi.org/10.1016/j.neulet.2012.01.080
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