dr. M. (Marco) Demaria

Research

  1. 2019
  2. Calcinotto, A., Kohli, J., Zagato, E., Pellegrini, L., Demaria, M., & Alimonti, A. (2019). Cellular Senescence: Aging, Cancer, and Injury. Physiological reviews, 99(2), 1047-1078. https://doi.org/10.1152/physrev.00020.2018
  3. Palmer, A. K., Xu, M., Zhu, Y., Pirtskhalava, T., Weivoda, M. M., Hachfeld, C. M., ... Kirkland, J. L. (2019). Targeting senescent cells alleviates obesity-induced metabolic dysfunction. Aging Cell, e12950. https://doi.org/10.1111/acel.12950
  4. 2018
  5. Demaria, M. (2018). Biomarkers for cellular senescence. (Patent No. WO2018164580).
  6. 2017
  7. Campisi, J., van Deursen, J. M. A., Kirkland, J. L., Tchkonia, T., Baker, D. J., & Demaria, M. (2017). Animal models for cancer and uses thereof. (Patent No. US20170042129).
  8. van Deursen, J. M. A., Baker, D. J., Kirkland, J. L., Tchkonia, T., Campisi, J., Demaria, M., & Laberge, R-M. (2017). Animal models of age-related disorders and age-sensitive traits associated with senescence-inducing stimuli and uses thereof. (Patent No. US2017027139).
  9. Demaria, M., O'Leary, M. N., Chang, J., Shao, L., Liu, S., Alimirah, F., ... Campisi, J. (2017). Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse. Cancer discovery, 7(2), 165-176. https://doi.org/10.1158/2159-8290.CD-16-0241
  10. Laberge, R-M., Campisi, J., Davalos, A., Lopez-Dominguez , J. A., Demaria, M., David, N., ... Zhu, Y. (2017). Compositions and methods for treating senescence-associated diseases and disorders. (Patent No. WO2017008060).
  11. Demaria, M. (2017). Cellular Senescence and Tumor Promotion. In M. Extermann (Ed.), Geriatric Oncology (pp. 1-15). Springer. https://doi.org/10.1007/978-3-319-44870-1_79-1
  12. 2016
  13. Chinta, S. J., Woods, G., Demaria, M., Campisi, J., & Andersen, J. K. (2016). Cellular senescence induced by paraquat drives neuropathology associated with Parkinson's disease. Movement Disorders, 31, S252-S252. [776].
  14. 2015
  15. Kang, C., Xu, Q., Martin, T. D., Li, M. Z., Demaria, M., Aron, L., ... Elledge, S. J. (2015). The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. Science, 349(6255), aaa5612. https://doi.org/10.1126/science.aaa5612
  16. Chinta, S. J., Woods, G., Rane, A., Demaria, M., Campisi, J., & Andersen, J. K. (2015). Cellular senescence and the aging brain. Experimental Gerontology, 68, 3-7. https://doi.org/10.1016/j.exger.2014.09.018
  17. Laberge, R-M., Orjalo, A. V., Patil, C. K., Freund, A., Zhou, L., Curran, S. C., ... Campisi, J. (2015). MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nature Cell Biology, 17(8), 1049-61. https://doi.org/10.1038/ncb3195
  18. Christy, B., Demaria, M., Campisi, J., Huang, J., Jones, D., Dodds, S. G., ... Hasty, P. (2015). p53 and rapamycin are additive. Oncotarget, 6(18), 15802-13. https://doi.org/10.18632/oncotarget.4602
  19. 2014
  20. Demaria, M., Ohtani, N., Youssef, S. A., Rodier, F., Toussaint, W., Mitchell, J. R., ... Campisi, J. (2014). An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Developmental Cell, 31(6), 722-33. https://doi.org/10.1016/j.devcel.2014.11.012
  21. Chinta, S. J., Wood, G., Lieu, C., Rane, A., DeMaria, M., Campisi, J., & Andersen, J. K. (2014). CELLULAR SENESCENCE AND BRAIN AGING. Free Radical Biology and Medicine, 76(1), S3-S3. https://doi.org/10.1016/j.freeradbiomed.2014.10.013
  22. Camporeale, A., Demaria, M., Monteleone, E., Giorgi, C., Wieckowski, M. R., Pinton, P., & Poli, V. (2014). STAT3 Activities and Energy Metabolism: Dangerous Liaisons. Cancers, 6(3), 1579-96. https://doi.org/10.3390/cancers6031579
  23. 2013
  24. Laberge, R-M., Adler, D., DeMaria, M., Mechtouf, N., Teachenor, R., Cardin, G. B., ... Rodier, F. (2013). Mitochondrial DNA damage induces apoptosis in senescent cells. Cell death & disease, 4, [e727]. https://doi.org/10.1038/cddis.2013.199
  25. 2012
  26. Laberge, R-M., Zhou, L., Sarantos, M. R., Rodier, F., Freund, A., de Keizer, P. L. J., ... Campisi, J. (2012). Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell, 11(4), 569-78. https://doi.org/10.1111/j.1474-9726.2012.00818.x
  27. Haines, B., Demaria, M., Mao, X., Xie, L., Campisi, J., Jin, K., & Greenberg, D. A. (2012). Hypoxia-inducible factor-1 and neuroglobin expression. Neuroscience Letters, 514(2), 137-40. https://doi.org/10.1016/j.neulet.2012.01.080
  28. 2011
  29. Riess, I., Sala, V., Leo, C., Demaria, M., Gatti, S., Gallo, S., ... Crepaldi, T. (2011). A mouse model for spatial and temporal expression of HGF in the heart. Transgenic Research, 20(6), 1203-16. https://doi.org/10.1007/s11248-011-9485-y
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