dr. ir. M.C. (Martijn) Nawijn

Associate Professor

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E-mail:
m.c.nawijn umcg.nl

Research

  1. 2021
  2. 2020
  3. Aliee, H., Massip, F., Qi, C., Stella de Biase, M., van Nijnatten, J. L., Kersten, E. T. G., Kermani, N. Z., Khuder, B., Vonk, J. M., Vermeulen, R. C. H., Neighbors, M., Tew, G. W., Grimbaldeston, M., Ten Hacken, N. H. T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P. S., ... Faiz, A. (2020). Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways. medRxiv : the preprint server for health sciences. https://doi.org/10.1101/2020.08.31.20169946
  4. Qi, C., Jiang, Y., Yang, I. V., Forno, E., Wang, T., Vonk, J. M., Gehring, U., Smit, H. A., Milanzi, E. B., Carpaij, O. A., Berg, M., Hesse, L., Brouwer, S., Cardwell, J., Vermeulen, C. J., Acosta-Pérez, E., Canino, G., Boutaoui, N., van den Berge, M., ... Koppelman, G. H. (2020). Nasal DNA methylation profiling of asthma and rhinitis. Journal of Allergy and Clinical Immunology, 145(6), 1655-1663. https://doi.org/10.1016/j.jaci.2019.12.911
  5. HCA Lung Biological Network. Electronic address: lung-network@humancellatlas.org, Ziegler, C. G. K., Allon, S. J., Nyquist, S. K., Mbano, I. M., Miao, V. N., Tzouanas, C. N., Cao, Y., Yousif, A. S., Bals, J., Hauser, B. M., Feldman, J., Muus, C., Wadsworth, M. H., Kazer, S. W., Hughes, T. K., Doran, B., Gatter, G. J., Vukovic, M., ... Theis, F. J. (2020). SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell, 181(5), 1016-1035.e19. https://doi.org/10.1016/j.cell.2020.04.035
  6. Portelli, M. A., Dijk, F. N., Ketelaar, M. E., Shrine, N., Hankinson, J., Bhaker, S., Grotenboer, N. S., Obeidat, M., Henry, A. P., Billington, C. K., Shaw, D., Johnson, S. R., Pogson, Z. E., Fogarty, A., McKeever, T. M., Nickle, D. C., Bossé, Y., van den Berge, M., Faiz, A., ... Sayers, I. (2020). Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI Insight, 5(8), [132446]. https://doi.org/10.1172/jci.insight.132446
  7. Boudewijn, I. M., Lan, A., Faiz, A., Cox, C. A., Brouwer, S., Schokker, S., Vroegop, S. J., Nawijn, M. C., Woodruff, P. G., Christenson, S. A., Hagedoorn, P., Frijlink, H. W., Choy, D. F., Brouwer, U., Wisman, M., Postma, D. S., Fingleton, J., Beasley, R., van den Berge, M., & Guryev, V. (2020). Nasal gene expression changes with inhaled corticosteroid treatment in asthma. Allergy, 75(1), 191-194. https://doi.org/10.1111/all.13952
  8. Ketelaar, M. E., Portelli, M. A., Dijk, F. N., Shrine, N., Faiz, A., Vermeulen, C. J., Xu, C. J., Hankinson, J., Bhaker, S., Henry, A. P., Billington, C. K., Shaw, D. E., Johnson, S. R., Benest, A. V., Pang, V., Bates, D., Pogson, Z. E. K., Fogarty, A., McKeever, T. M., ... Nawijn, M. C. (2020). Phenotypic and functional translation of IL33 genetics in asthma. Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2020.04.051
  9. 2019
  10. Dijk, F. N., Vijverberg, S. J., Hernandez-Pacheco, N., Repnik, K., Karimi, L., Mitratza, M., Farzan, N., Nawijn, M. C., Burchard, E. G., Engelkes, M., Verhamme, K. M., Potočnik, U., Pino-Yanes, M., Postma, D. S., Maitland-van der Zee, A., & Koppelman, G. H. (2019). IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids. Allergy, 75(4), 984-989. https://doi.org/10.1111/all.14125
  11. Braga, F. A. V., Kar, G., Berg, M., Carpaij, O. A., Polanski, K., Simon, L. M., Brouwer, S., Gomes, T., Hesse, L., Jiang, J., Fasouli, E. S., Efremova, M., Vento-Tormo, R., Talavera-Lopez, C., Jonker, M. R., Affleck, K., Palit, S., Strzelecka, P. M., Firth, H. V., ... Teichmann, S. A. (2019). A cellular census of human lungs identifies novel cell states in health and in asthma. Nature Medicine, 25(7), 1153-1163. https://doi.org/10.1038/s41591-019-0468-5
  12. Schiller, H. B., Montoro, D. T., Simon, L. M., Rawlins, E. L., Meyer, K. B., Strunz, M., Vieira Braga, F., Timens, W., Koppelman, G. H., Budinger, G. R. S., Burgess, J. K., van den Berge, M., Theis, F. J., Regev, A., Kaminski, N., Rajagopal, J., Teichmann, S. A., Misharin, A. V., & Nawijn, M. C. (2019). The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease. American Journal of Respiratory Cell and Molecular Biology, 61(1), 31-41. https://doi.org/10.1165/rcmb.2018-0416TR
  13. Taylor, D. M., Aronow, B. J., Tan, K., Bernt, K., Salomonis, N., Greene, C. S., Frolova, A., Henrickson, S. E., Wells, A., Pei, L., Jaiswal, J. K., Whitsett, J., Hamilton, K. E., MacParland, S. A., Kelsen, J., Heuckeroth, R. O., Potter, S. S., Vella, L. A., Terry, N. A., ... White, P. S. (2019). The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental Cell, 49(1), 10-29. https://doi.org/10.1016/j.devcel.2019.03.001
  14. Braga, F. V., Kar, G., Berg, M., Carpaij, O., polanski, K., Simon, L., Brouwer, S., Gomes, T., Hesse, L., Jiang, J., Fasouli, E. S., Efremova, M., Vento-Tormo, R., Affleck, K., Palit, S., strzelecka, P., Firth, H. V., Mahbubani, K. T. A., Cvejic, A., ... Teichmann, S. A. (2019). A cellular census of healthy lung and asthmatic airway wall identifies novel cell states in health and disease. Manuscript submitted for publication. https://doi.org/10.1101/527408
  15. Ketelaar, M., Portelli, M. A., Dijk, F. N., Faiz, A., Shrine, N., Hankinson, J., Bhaker, S., Henry, A. P., Billington, C. K., Shaw, D., Johnson, S. R., Benest, A. V., Pogson, Z. E. K., Fogarty, A., McKeever, T. M., Singapuri, A., Heaney, L., Mansur, A., Gaudhuri, R., ... Nawijn, M. C. (2019). Functional Translation of IL33 Locus Polymorphisms Into Altered Epithelial Cell Function Underlying Asthma. American Journal of Respiratory and Critical Care Medicine, 199.
  16. 2018
  17. Xu, C-J., Söderhäll, C., Bustamante, M., Baïz, N., Gruzieva, O., Gehring, U., Mason, D., Chatzi, L., Basterrechea, M., Llop, S., Torrent, M., Forastiere, F., Fantini, M. P., Carlsen, K. C. L., Haahtela, T., Morin, A., Kerkhof, M., Merid, S. K., van Rijkom, B., ... BIOS Consortium (2018). DNA methylation in childhood asthma: an epigenome-wide meta-analysis. The Lancet. Respiratory Medicine, 6(5), 379-388. https://doi.org/10.1016/S2213-2600(18)30052-3
  18. Dijk, F. N., Xu, C., Melén, E., Carsin, A-E., Kumar, A., Nolte, I. M., Gruzieva, O., Pershagen, G., Grotenboer, N. S., Savenije, O. E. M., Antó, J. M., Lavi, I., Dobaño, C., Bousquet, J., van der Vlies, P., van der Valk, R. J. P., de Jongste, J. C., Nawijn, M. C., Guerra, S., ... Koppelman, G. H. (2018). Genetic regulation ofmethylation and IL1RL1-a protein levels in asthma. European Respiratory Journal, 51(3). https://doi.org/10.1183/13993003.01377-2017
  19. 2017
  20. Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P. J., Carninci, P., Clatworthy, M., Clevers, H., Deplancke, B., Dunham, I., Eberwine, J., Eils, R., Enard, W., Farmer, A., Fugger, L., Göttgens, B., ... Human Cell Atlas Meeting Participants (2017). Science Forum: The Human Cell Atlas. eLife, 6, [e27041]. https://doi.org/10.7554/eLife.27041
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