dr. L.C.L.T. (Léon) van Kempen

Clinical Scientist in Molecular Pathology

dr. L.C.L.T. (Léon) van Kempen
Telephone:
+31 50 361 5129 (Office)
Staff assistant:
+31 50 361 0020 (Mrs. Annet Bouman - Van der Jagt)
E-mail:
l.van.kempen umcg.nl

Research

  1. 2020
  2. Janssen, S. M., Moscona, R., Elchebly, M., Papadakis, A. I., Redpath, M., Wang, H., ... Spatz, A. (2020). BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells. Cell Death and Discovery, 6(1), [1]. https://doi.org/10.1038/s41420-019-0235-x
  3. 2019
  4. 2018
  5. Ali, A., Tamber, G. S., Camilleri-Broet, S., Cohen, V., Spicer, J., Wang, H., ... Agulnik, J. (2018). Reducing Time to Molecular Diagnosis for Advanced NSCLC in the Context of a Reference Testing Center. Journal of Thoracic Oncology, 13(10), S666-S666. https://doi.org/10.1016/j.jtho.2018.08.1058
  6. Leroux, L-P., Lorent, J., Graber, T. E., Chaparro, V., Masvidal, L., Aguirre, M., ... Jaramillo, M. (2018). The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome. Infection and Immunity, 86(9), [ARTN e00244-18]. https://doi.org/10.1128/IAI.00244-18
  7. William, M., Leroux, L-P., Chaparro, V., Lorent, J., Graber, T. E., M'Boutchou, M-N., ... Jaramillo, M. (2018). eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2. Journal of Immunology, 200(12), 4102-4116. https://doi.org/10.4049/jimmunol.1701670
  8. Wang, H., Agulnik, J., Kasymjanova, G., Wang, A., Jiménez, P., Cohen, V., ... Spatz, A. (2018). Cytology cell blocks are suitable for immunohistochemical testing for PD-L1 in lung cancer. Annals of Oncology, 29(6), 1417-1422. https://doi.org/10.1093/annonc/mdy126
  9. 2017
  10. 2016
  11. Geels, Y. P., Pijnenborg, J. M. A., Gordon, B. B. M., Fogel, M., Altevogt, P., Masadah, R., ... Massuger, L. F. A. G. (2016). L1CAM Expression is Related to Non-Endometrioid Histology, and Prognostic for Poor Outcome in Endometrioid Endometrial Carcinoma. Pathology & oncology research, 22(4), 863-868. https://doi.org/10.1007/s12253-016-0047-8
  12. Krayem, M., Journe, F., Wiedig, M., Morandini, R., Najem, A., Salès, F., ... Ghanem, G. (2016). p53 Reactivation by PRIMA-1(Met) (APR-246) sensitises (V600E/K)BRAF melanoma to vemurafenib. European Journal of Cancer, 55, 98-110. https://doi.org/10.1016/j.ejca.2015.12.002
  13. 2015
  14. Conde-Perez, A., Gros, G., Longvert, C., Pedersen, M., Petit, V., Aktary, Z., ... Larue, L. (2015). A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity. Nature Communications, 6, 8093. https://doi.org/10.1038/ncomms9093
  15. Zhan, Y., Dahabieh, M. S., Rajakumar, A., Dobocan, M. C., M'Boutchou, M-N., Goncalves, C., ... Miller, W. H. (2015). The role of eIF4E in response and acquired resistance to vemurafenib in melanoma. Journal of Investigative Dermatology, 135(5), 1368-1376. https://doi.org/10.1038/jid.2015.11
  16. 2014
  17. Govaere, O., Komuta, M., Berkers, J., Spee, B., Janssen, C., de Luca, F., ... Roskams, T. (2014). Keratin 19: a key role player in the invasion of human hepatocellular carcinomas. Gut, 63(4), 674-85. https://doi.org/10.1136/gutjnl-2012-304351
  18. 2013
  19. Zeimet, A. G., Reimer, D., Huszar, M., Winterhoff, B., Puistola, U., Azim, S. A., ... Fogel, M. (2013). L1CAM in early-stage type I endometrial cancer: results of a large multicenter evaluation. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 105(15), 1142-50. https://doi.org/10.1093/jnci/djt144
  20. 2012
  21. van den Einden, L. C. G., Grefte, J. M. M., van der Avoort, I. A. M., Vedder, J. E. M., van Kempen, L. C. L. T., Massuger, L. F. A. G., & de Hullu, J. A. (2012). Cytology of the vulva: feasibility and preliminary results of a new brush. British Journal of Cancer, 106(2), 269-73. https://doi.org/10.1038/bjc.2011.533
  22. Testori, A., Suciu, S., van Akkooi, A., Cook, M., Ghanem, G., Gurenath, R. K., ... Eggermont, A. (2012). EORTC Melanoma Group achievements. Ejc supplements, 10(1), 112-119. https://doi.org/10.1016/S1359-6349(12)70020-4
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