prof. dr. K.N. (Klaas Nico) Faber
Associate professor / adjunct professor
Telephone:
E-mail:
k.n.faber umcg.nl
Research
1 - 50 out of 136Page size: 50
- 2019
- Bourgonje, A. R., von Martels, J. Z. H., Gabriëls, R. Y., Blokzijl, T., Buist-Homan, M., Heegsma, J., ... Dijkstra, G. (2019). A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease. Frontiers in Medicine, 6, [251].
- Vich Vila, A., Boddeke, A., Kurilshikov, A., Collij, V., Sureda Horrach, P., Martels ,von, J. Z. H., ... Weersma, R. K. (2019). Combining absolute quantification of fecal bacteria with metagenomic sequencing data improves the characterization of the gut microbiome of patients with Crohn’s disease. United European Gastroenterology Journal.
- Saeed, A., Yang, J., Heegsma, J., Groen, A. K., Van Mil, S. W. C., Paulusma, C. C., ... Faber, K. N. (2019). Farnesoid x receptor and bile acids regulate vitamin a storage. Hepatology, 70, 1222A-1222A.
- Sydor, S., Manka, P., Van Buren, L., Heegsma, J., Best, J., Baba, H., ... Bechmann, L. P. (2019). KLF6 INTERACTS WITH FXR TARGET GENES AND EFFECTS THE OUTCOME OF PRIMARY SCLEROSING CHOLANGITIS. Hepatology, 70, 805A-805A.
- Bourgonje, A. R., Gabriëls, R. Y., Borst, de, M. H., Bulthuis, M. L. C., Faber, K. N., van Goor, H., & Dijkstra, G. (2019). Levels of serum free thiols are superior to fecal calprotectin in predicting endoscopic disease activity in Inflammatory Bowel Disease. United European Gastroenterology Journal, 7(8(Suppl)), 137-138. [P0352].
- von Martels, J. Z. H., Bourgonje, A. R., Klaassen, M. A. Y., Alkhalifah, H. A. A., Sadaghian Sadabad, M., Vich Vila, A., ... Dijkstra, G. (2019). Riboflavin suppresses inflammation and attenuates Crohn’s disease symptoms (RISE-UP Study). United European Gastroenterology Journal, 7(8(Suppl)), 460-461. [P0683].
- Fagundes Rosa, R. R., Bourgonje, A. R., Barbieri, R., Jansen, D., Taylor, C. T., Faber, K. N., & Dijkstra, G. (2019). Systemic iron deficiency is associated with activation of the HIF-1α pathway in the intestinal mucosa of patients with Inflammatory Bowel Disease. United European Gastroenterology Journal.
- Bourgonje, A. R., Gabriëls, R. Y., Borst, de, M. H., Bulthuis, M. L. C., Faber, K. N., van Goor, H., & Dijkstra, G. (2019). Serum Free Thiols Are Superior to Fecal Calprotectin in Reflecting Endoscopic Disease Activity in Inflammatory Bowel Disease. Antioxidants (Basel, Switzerland), 8(9), [351]. https://doi.org/10.3390/antiox8090351
- Shajari, S., Saeed, A., Smith-Cortinez, N. F., Heegsma, J., Sydor, S., & Faber, K. N. (2019). Hormone-sensitive lipase is a retinyl ester hydrolase in human and rat quiescent hepatic stellate cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1864(9), 1258-1267. https://doi.org/10.1016/j.bbalip.2019.05.012
- Parada Venegas, D., De la Fuente, M. K., Landskron, G., Julieta Gonzalez, M., Quera, R., Dijkstra, G., ... Hermoso, M. A. (2019). Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases (vol 10, 277, 2019). Frontiers in Immunology, 10, [1486]. https://doi.org/10.3389/fimmu.2019.01486
- Bourgonje, A. R., Gabriëls, R. Y., von Martels, J. Z. H., Blokzijl, T., Buist-Homan, M., Heegsma, J., ... Dijkstra, G. (2019). A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease. Gastroenterology, 156(6), S848. [Mo1814]. https://doi.org/10.1016/S0016-5085(19)39081-X
- Fagundes Rosa, R. R., Bourgonje, A. R., Sadaghian Sadabad, M., van Leeuwen, S. S., Harmsen, H. J. M., Dijkstra, G., & Faber, K. N. (2019). Reconstitution of Prebiotic-Driven Host-Microbe Syntrophy in the Colon; Inulin-Grown Faecalibacterium prausnitzii Cross-Feeds the Human Intestinal Epithelium. Gastroenterology, 156(6), S895. [Mo1946]. https://doi.org/10.1016/S0016-5085(19)39209-1
- Fagundes Rosa, R. R., Bourgonje, A. R., Cui, Y., Blokzijl, T., Harmsen, H. J. M., Dijkstra, G., ... Faber, K. N. (2019). The Intestinal Microenvironment Induces a Transcription Reprogramming of Epithelial Oxygen Sensing. Gastroenterology, 156(6), S37. [157]. https://doi.org/10.1016/S0016-5085(19)36870-2
- Bourgonje, A. R., von Martels, J. Z. H., Bulthuis, M. L. C., van Londen, M., Faber, K. N., Dijkstra, G., & van Goor, H. (2019). Crohn's Disease in Clinical Remission Is Marked by Systemic Oxidative Stress. Frontiers in Physiology, 10, [499]. https://doi.org/10.3389/fphys.2019.00499
- Parada Venegas, D., De la Fuente, M. K., Landskron, G., Julieta Gonzalez, M., Quera, R., Dijkstra, G., ... Hermoso, M. A. (2019). Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases. Frontiers in Immunology, 10, [277]. https://doi.org/10.3389/fimmu.2019.00277
- Uniken Venema, W. T., Voskuil, M. D., Vich Vila, A., van der Vries, G., Jansen, B. H., Jabri, B., ... Festen, E. A. (2019). Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets. Gastroenterology, 156(3), 812-+. https://doi.org/10.1053/j.gastro.2018.10.046
- Bourgonje, A. R., von Martels, J. Z. H., Gabriëls, R. Y., Blokzijl, T., Buist-Homan, M., Heegsma, J., ... Dijkstra, G. (2019). A combined set of four serum inflammatory biomarkers reliably predicts endoscopic disease activity in inflammatory bowel disease. Journal of Crohn's and Colitis, 13(1).
- Ríos-Ocampo, W. A., Daemen, T., Buist-Homan, M., Faber, K. N., Navas, M-C., & Moshage, H. (2019). Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes against oxidative stress and endoplasmic reticulum stress. Redox Report, 24(1), 17-26. https://doi.org/10.1080/13510002.2019.1596431
- Wessel, H., Saeed, A., Heegsma, J., Connelly, M. A., Faber, K. N., & Dullaart, R. P. F. (2019). Plasma Levels of Retinol Binding Protein 4 Relate to Large VLDL and Small LDL Particles in Subjects with and without Type 2 Diabetes. Journal of Clinical Medicine, 8(11). https://doi.org/10.3390/jcm8111792
- 2018
- Buurman, D. J., Blokzijl, T., Festen, E. A. M., Pham, B. T., Faber, K. N., Brouwer, E., & Dijkstra, G. (2018). Quantitative comparison of the neutralizing capacity, immunogenicity and cross-reactivity of anti-TNF-alpha biologicals and an Infliximab-biosimilar. PLoS ONE, 13(12), [0208922]. https://doi.org/10.1371/journal.pone.0208922
- Sydor, S., Wenning, C., Assmuth, S., Messerschmidt, I., Best, J., Moshage, H., ... Bechmann, L. P. (2018). Effects of a Single Fast Food Binge on Hepatic Steatosis, Bile Acid Metabolism, and Cytokine Profiles. Hepatology, 68, 1023A.
- Saeed, A., Bartuzi, P., Heegsma, J., Dekker, D., Kloosterhuis, N., De Bruin, A., ... Faber, K. N. (2018). Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes. Hepatology, 68, 738A-739A.
- Smith-Cortinez, N., Van Eunen, K., Sydor, S., Bechmann, L. P., Moshage, H., Thediek, K., ... Faber, K. N. (2018). Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Targets to Treat Liver Fibrosis. Hepatology, 68, 642A.
- Visschedijk, M. C., Spekhorst, L. M., Cheng, S-C., van Loo, E. S., Jansen, B. H. D., Blokzijl, T., ... Festen, E. A. M. (2018). Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease. Journal of Crohn's and Colitis, 12(5), 582-588. https://doi.org/10.1093/ecco-jcc/jjy001
- Sydor, S., Manka, P. P., Schaenzer, J., Messerschmidt, I., Kinner, S., Link, A., ... Bechmann, L. P. (2018). Gut-liver interactions in celiac disease: FGF-19 and GLP-1 link disease activity to hepatic steatosis and liver injury. S561-S561. Poster session presented at International Liver Congress (ILC), Paris, France. https://doi.org/10.1016/S0168-8278(18)31378-3
- Saeed, A., Dullaart, R. P. F., Schreuder, T. C. M. A., Blokzijl, H., & Faber, K. N. (2018). Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD). Nutrients, 10(1), [29]. https://doi.org/10.3390/nu10010029
- 2017
- Atanasovska, B., Rensen, S. S., van der Sijde, M. R., Marsman, G., Kumar, V., Jonkers, I., ... Fu, J. (2017). A Liver-Specific Long Noncoding RNA With a Role in Cell Viability Is Elevated in Human Nonalcoholic Steatohepatitis. Hepatology, 66(3), 794-808. https://doi.org/10.1002/hep.29034
- Sydor, S., Manka, P., Best, J., Jafoui, S., Sowa, J-P., Zoubek, M. E., ... Bechmann, L. P. (2017). Kruppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury. Scientific Reports, 7(1), [8119]. https://doi.org/10.1038/s41598-017-08680-w
- Nass, K. J., van den Berg, E. H., Faber, K. N., Schreuder, T. C. M. A., Blokzijl, H., & Dullaart, R. P. F. (2017). High prevalence of apolipoprotein B dyslipoproteinemias in non-alcoholic fatty liver disease: The lifelines cohort study. Metabolism, 72, 37-46. https://doi.org/10.1016/j.metabol.2017.04.004
- Saeed, A., Hoekstra, M., Hoeke, M. O., Heegsma, J., & Faber, K. N. (2017). The interrelationship between bile acid and vitamin A homeostasis. Biochimica et biophysica acta-Molecular and cell biology of lipids, 1862(5), 496-512. https://doi.org/10.1016/j.bbalip.2017.01.007
- von Martels, J. Z. H., Sadabad, M. S., Bourgonje, A. R., Blokzijl, T., Dijkstra, G., Faber, K. N., & Harmsen, H. J. M. (2017). The role of gut microbiota in health and disease: In vitro modeling of host-microbe interactions at the aerobe-anaerobe interphase of the human gut. Anaerobe, 44, 3-12. https://doi.org/10.1016/j.anaerobe.2017.01.001
- van den Berg, E. H., van Tienhoven-Wind, L. J. N., Amini, M., Schreuder, T. C. M. A., Faber, K. N., Blokzijl, H., & Dullaart, R. P. F. (2017). Higher free triiodothyronine is associated with non-alcoholic fatty liver disease in euthyroid subjects: The Lifelines Cohort Study. Metabolism, 67, 62-71. https://doi.org/10.1016/j.metabol.2016.11.002
- Haanstra, J. R., Gerding, A., Dolga, A. M., Sorgdrager, F. J. H., Buist-Homan, M., du Toit, F., ... Bakker, B. M. (2017). Targeting pathogen metabolism without collateral damage to the host. Scientific Reports, 7, [40406]. https://doi.org/10.1038/srep40406
- Bai, X., Yang, P., Zhou, Q., Cai, B., Buist-Homan, M., Cheng, H., ... Shi, G. (2017). The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro. British Journal of Pharmacology, 174(1), 41-56. https://doi.org/10.1111/bph.13645
- 2016
- Van Den Berg, E., van Tienhoven-Wind, L., Amini, M., Schreuder, T. C. M. A., Faber, K. N., Blokzijl, H., & Dullaart, R. P. F. (2016). Free triiodothyronine as determinant of non-alcoholic fatty liver disease in euthyroid subjects: The lifelines cohort study. Metabolism Clinical and Experimental.
ID: 71635