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prof. dr. J.L. (Hans) Hillege

Cardiology

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  1. 2019
  2. ASIAN-HF Investigators (2019). Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study. The Lancet. https://doi.org/10.1016/S0140-6736(19)31792-1
  3. Roldan, S., Postmus, D., De Vries, S., Mol, P., & Hillege, H. (2019). Patient-, disease- and treatment related factors that impact values attached to drug effects: A preferences study among patients with type 2 diabetes. Pharmacoepidemiology and Drug Safety, 28, 220.
  4. Abbasi, A., Corpeleijn, E., Meijer, E., Postmus, D., Gansevoort, R. T., Gans, R. O. B., ... Bakker, S. J. L. (2019). Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study (vol 59, pg 1963, 2012). Diabetologia, 62(8), 1518-1519. https://doi.org/10.1007/s00125-019-4917-y
  5. Markousis-Mavrogenis, G., Tromp, J., Ouwerkerk, W., Devalaraja, M., Anker, S. D., Cleland, J. G., ... van der Meer, P. (2019). The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study. European Journal of Heart Failure, 21(8), 965-973. https://doi.org/10.1002/ejhf.1482
  6. Suzuki, T., Yazaki, Y., Voors, A. A., Jones, D. J. L., Chan, D. C. S., Anker, S. D., ... Ng, L. L. (2019). Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure: results from BIOSTAT-CHF. European Journal of Heart Failure, 21(7), 877-886. https://doi.org/10.1002/ejhf.1338
  7. Mordi, I. R., Santema, B. T., Kloosterman, M., Choy, A-M., Rienstra, M., van Gelder, I., ... Lang, C. C. (2019). Prognostic significance of changes in heart rate following uptitration of beta-blockers in patients with sub-optimally treated heart failure with reduced ejection fraction in sinus rhythm versus atrial fibrillation. Clinical Research in Cardiology, 108(7), 797-805. https://doi.org/10.1007/s00392-018-1409-x
  8. Tromp, J. J., Voors, A. A., Sharma, A., Ferreira, J. P., Ouwerkerk, W., Hillege, H. L., ... Sama, I. (2019). Diabetes is associated with unique pathological mechanisms in heart failure. European Journal of Heart Failure, 21, 432.
  9. Markousis-Mavrogenis, G., Tromp, J., Ouwerkerk, W., Devalaraja, M., Filippatos, G., Van Der Harst, P., ... Van Der Meer, P. (2019). The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study. European Journal of Heart Failure, 21, 111.
  10. Makady, A., van Acker, S., Nijmeijer, H., de Boer, A., Hillege, H., Klungel, O., & Goettsch, W. (2019). Conditional Financing of Drugs in the Netherlands: Past, Present, and Future-Results From Stakeholder Interviews. Value in Health, 22(4), 399-407. https://doi.org/10.1016/j.jval.2018.11.016
  11. Gruppen, E., Kunutsor, S., Kieneker, L., van der Vegt, B., Connelly, M., Hillege, H., ... Dullaart, R. (2019). GlycA, a novel pro-inflammatory glycoprotein biomarker predicts mortality: Results from The PREVEND study and meta-analysis. European Journal of Clinical Investigation, 49, 74-75.
  12. Cao, Q., Buskens, E., Hillege, H. L., Jaarsma, T., Postma, M., & Postmus, D. (2019). Stratified treatment recommendation or one-size-fits-all? A health economic insight based on graphical exploration. European Journal of Health Economics, 20(3), 475-482. https://doi.org/10.1007/s10198-018-1013-z
  13. RACE 3 Investigators (2019). Targeted therapy of underlying conditions improves quality of life in patients with persistent atrial fibrillation: results of the RACE 3 study. Europace, 21(4), 563-571. https://doi.org/10.1093/europace/euy311
  14. Makady, A., van Veelen, A., de Boer, A., Hillege, H., Klungel, O. H., & Goettsch, W. (2019). Implementing managed entry agreements in practice: The Dutch reality check. Health Policy, 123(3), 267-274. https://doi.org/10.1016/j.healthpol.2018.09.016
  15. Emerging Risk Factors Collaboratio (2019). Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies. European Heart Journal, 40(7), 621-631. https://doi.org/10.1093/eurheartj/ehy653
  16. Ferreira, J. P., Metra, M., Mordi, I., Gregson, J., ter Maaten, J. M., Tromp, J., ... Zannad, F. (2019). Heart failure in the outpatient versus inpatient setting: Findings from the BIOSTAT-CHF study. European Journal of Heart Failure, 21(1), 112-120. https://doi.org/10.1002/ejhf.1323
  17. 2018
  18. Tromp, J., Ouwerkerk, W., Demissei, B. G., Anker, S. D., Cleland, J. G., Dickstein, K., ... van der Meer, P. (2018). Novel endotypes in heart failure: effects on guideline-directed medical therapy. European Heart Journal, 39(48), 4269-4276. https://doi.org/10.1093/eurheartj/ehy712
  19. Kraai, I. H., Vermeulen, K. M., Hillege, H. L., Jaarsma, T., & Hoekstra, T. (2018). Optimism and quality of life in patients with heart failure. Palliative & supportive care, 16(6), 725-731. https://doi.org/10.1017/S1478951517001055
  20. GetReal Workpackage 1 (2018). Social media as a tool for assessing patient perspectives on quality of life in metastatic melanoma: A feasibility study. HEALTH AND QUALITY OF LIFE OUTCOMES, 16, [222]. https://doi.org/10.1186/s12955-018-1047-z
  21. Streng, K. W., Nauta, J. F., Hillege, H. L., Anker, S. D., Cleland, J. G., Dickstein, K., ... Voors, A. A. (2018). Non-cardiac comorbidities in heart failure with reduced, mid-range and preserved ejection fraction. International Journal of Cardiology, 271, 132-139. https://doi.org/10.1016/j.ijcard.2018.04.001
  22. Santema, B. T., Kloosterman, M., Van Gelder, I. C., Mordi, I., Lang, C. C., Lam, C. S. P., ... Voors, A. A. (2018). Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction. European Heart Journal, 39(43), 3867-3875. https://doi.org/10.1093/eurheartj/ehy421
  23. Thong Huy Cao, Jones, D. J. L., Quinn, P. A., Chan, D. C. S., Hafid, N., Parry, H. M., ... Ng, L. L. (2018). Using matrix assisted laser desorption ionisation mass spectrometry (MALDI-MS) profiling in order to predict clinical outcomes of patients with heart failure. Clinical proteomics, 15, [35]. https://doi.org/10.1186/s12014-018-9213-1
  24. Linssen, G. C. M., Jaarsma, T., Hillege, H. L., Voors, A. A., & van Veldhuisen, D. J. (2018). A comparison of the prognostic value of BNP versus NT-proBNP after hospitalisation for heart failure. Netherlands Heart Hournal, 26(10), 486-492. https://doi.org/10.1007/s12471-018-1145-x
  25. Tromp, J., Westenbrink, B. D., Ouwerkerk, W., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., ... Voors, A. A. (2018). Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction. Journal of the American College of Cardiology, 72(10), 1081-1090. https://doi.org/10.1016/j.jacc.2018.06.050
  26. Streng, K. W., Voors, A. A., Hillege, H. L., Anker, S. D., Cleland, J. G., Dickstein, K., ... Lang, C. C. (2018). Waist-to-hip ratio and mortality in heart failure. European Journal of Heart Failure, 20(9), 1269-1277. https://doi.org/10.1002/ejhf.1244
  27. Rienstra, M., Hobbelt, A. H., Alings, M., Tijssen, J. G. P., Smit, M. D., Brügemann, J., ... RACE 3 Investigators (2018). Targeted therapy of underlying conditions improves sinus rhythm maintenance in patients with persistent atrial fibrillation: Results of the RACE 3 trial. European Heart Journal, 39(32), 2987-2996. https://doi.org/10.1093/eurheartj/ehx739
  28. Ataher, Q. S., Postmus, D., Hillege, H. L., & Tervonen, T. (2018). Quantitative benefit-risk assessment: Hands-on workshop. Pharmacoepidemiology and Drug Safety, 27, 360.
  29. Savji, N., Meijers, W. C., Bartz, T. M., Bhambhani, V., Cushman, M., Nayor, M., ... Ho, J. E. (2018). The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF. JACC. Heart failure, 6(8), 701-709. https://doi.org/10.1016/j.jchf.2018.05.018
  30. Lycholip, E., Aamodt, I. T., Lie, I., Simbelyte, T., Puronaite, R., Hillege, H., ... Celutkiene, J. (2018). The dynamics of self-care in the course of heart failure management: Data from the IN TOUCH study. Patient Preference and Adherence, 12, 1113-1122. https://doi.org/10.2147/PPA.S162219
  31. Juárez-Orozco, L. E., Alexanderson, E., Dierckx, R. A., Boersma, H. H., Hillege, J. L., Zeebregts, C. J., ... Slart, R. H. (2018). Stress myocardial blood flow correlates with ventricular function and synchrony better than myocardial perfusion reserve: A Nitrogen-13 ammonia PET study. Journal of Nuclear Cardiology, 25(3), 797-806. https://doi.org/10.1007/s12350-016-0669-y
  32. Beusekamp, J. C., Tromp, J., van der Wal, H. H., Anker, S. D., Cleland, J. G., Dickstein, K., ... van der Meer, P. (2018). Potassium and the use of renin-angiotensin-aldosterone system inhibitors in heart failure with reduced ejection fraction: data from BIOSTAT-CHF. European Journal of Heart Failure, 20(5), 923-930. https://doi.org/10.1002/ejhf.1079
  33. van den Berg, M. E., Rijnbeek, P. R., Niemeijer, M. N., Hofman, A., van Herpen, G., Bots, M. L., ... Kors, J. A. (2018). Normal Values of Corrected Heart-Rate Variability in 10-Second Electrocardiograms for All Ages. Frontiers in Physiology, 9, [424]. https://doi.org/10.3389/fphys.2018.00424
  34. Ferreira, J. P., Rossignol, P., Demissei, B., Sharma, A., Girerd, N., Anker, S. D., ... Zannad, F. (2018). Coronary angiography in worsening heart failure: Determinants, findings and prognostic implications. Heart, 104(7), 606-613. https://doi.org/10.1136/heartjnl-2017-311750
  35. Brankovic, M., Akkerhuis, K. M., van Boven, N., Anroedh, S., Constantinescu, A., Caliskan, K., ... Kardys, I. (2018). Patient-specific evolution of renal function in chronic heart failure patients dynamically predicts clinical outcome in the Bio-SHiFT study. Kidney International, 93(4), 952-960. https://doi.org/10.1016/j.kint.2017.09.013
  36. Bhambhani, V., Kizer, J. R., Lima, J. A. C., van der Harst, P., Bahrami, H., Nayor, M., ... Ho, J. E. (2018). Predictors and outcomes of heart failure with mid-range ejection fraction. European Journal of Heart Failure, 20(4), 651-659. https://doi.org/10.1002/ejhf.1091
  37. de Boer, R. A., Nayor, M., deFilippi, C. R., Enserro, D., Bhambhani, V., Kizer, J. R., ... Ho, J. E. (2018). Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. Jama cardiology, 3(3), 215-224. https://doi.org/10.1001/jamacardio.2017.4987
  38. Makady, A., van Veelen, A., Jonsson, P., Moseley, O., D'Andon, A., de Boer, A., ... Goettsch, W. (2018). Using Real-World Data in Health Technology Assessment (HTA) Practice: A Comparative Study of Five HTA Agencies. Pharmacoeconomics, 36(3), 359-368. https://doi.org/10.1007/s40273-017-0596-z
  39. ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G., ... de Borst, M. H. (2018). Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. International Journal of Cardiology, 253, 84-90. https://doi.org/10.1016/j.ijcard.2017.10.010
  40. Ploegstra, M-J., Brokelman, J. G. M., Roos-Hesselink, J. W., Douwes, J. M., van Osch-Gevers, L. M., Hoendermis, E. S., ... Berger, R. M. F. (2018). Pulmonary arterial stiffness indices assessed by intravascular ultrasound in children with early pulmonary vascular disease: Prediction of advanced disease and mortality during 20-year follow-up. European heart journal-Cardiovascular imaging, 19(2), 216-224. https://doi.org/10.1093/ehjci/jex015
  41. Kraai, I. H., Vermeulen, K. M., Hillege, H. L., & Jaarsma, T. (2018). "Not getting worse" a qualitative study of patients perceptions of treatment goals in patients with heart failure. Applied nursing research : ANR, 39, 41-45. https://doi.org/10.1016/j.apnr.2017.10.010
  42. Emmens, J. E., Jones, D. J. L., Cao, T. H., Chan, D. C. S., Romaine, S. P. R., Quinn, P. A., ... Ng, L. L. (2018). Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20(2), 260-267. https://doi.org/10.1002/ejhf.1101
  43. Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., ... Voors, A. A. (2018). Biomarker-Guided Versus Guideline-Based Treatment of Patients With Heart Failure Results From BIOSTAT-CHF. Journal of the American College of Cardiology, 71(4), 386-398. https://doi.org/10.1016/j.jacc.2017.11.041
  44. Arjaans, S., Zwart, E. A. H., Ploegstra, M-J., Bos, A. F., Kooi, E. M. W., Hillege, H. L., & Berger, R. M. F. (2018). Identification of gaps in the current knowledge on pulmonary hypertension in extremely preterm infants: A systematic review and meta-analysis. Paediatric and Perinatal Epidemiology. https://doi.org/10.1111/ppe.12444
  45. Postmus, D., Richard, S., Bere, N., van Valkenhoef, G., Galinsky, J., Low, E., ... Pignatti, F. (2018). Individual Trade-Offs Between Possible Benefits and Risks of Cancer Treatments: Results from a Stated Preference Study with Patients with Multiple Myeloma. The Oncologist, 23(1), 44-51. https://doi.org/10.1634/theoncologist.2017-0257
  46. van Boven, N., Kardys, I., van Vark, L. C., Akkerhuis, K. M., de Ronde, M. W. J., Khan, M. A. F., ... Postmus, D. (2018). Serially measured circulating microRNAs and adverse clinical outcomes in patients with acute heart failure. European Journal of Heart Failure, 20(1), 89-96. https://doi.org/10.1002/ejhf.950
  47. 2017
  48. Marcos, E. G., Geelhoed, B., Van der Harst, P., Bakker, S. J. L., Gansevoort, R. T., Hillege, H. L., ... Rienstra, M. (2017). Relation of renal dysfunction with incident atrial fibrillation and cardiovascular morbidity and mortality: The PREVEND study. Europace, 19(12), 1930-1936. https://doi.org/10.1093/europace/euw373
  49. van Vark, L. C., Lesman-Leegte, I., Baart, S. J., Postmus, D., Pinto, Y. M., de Boer, R. A., ... TRIUMPH (Translational Initiative on Unique and Novel Strategies for Management of Patients with Heart Failure) Investigators (2017). Prognostic Value of Serial Galectin-3 Measurements in Patients With Acute Heart Failure. Journal of the American Heart Association, 6(12), [003700]. https://doi.org/10.1161/JAHA.116.003700
  50. Pang, C., Kelpin, F., van Enckevort, D., Eklund, N., Silander, K., Hendriksen, D., ... Swertz, M. A. (2017). BiobankUniverse: Automatic matchmaking between datasets for biobank data discovery and integration. Bioinformatics, 33(22), 3627-3634. https://doi.org/10.1093/bioinformatics/btx478
  51. van Vark, L. C., Lesman-Leegte, I., Baart, S. J., Postmus, D., Pinto, Y. M., Orsel, J. G., ... TRIUMPH Investigators (2017). Prognostic Value of Serial ST2 Measurements in Patients With Acute Heart Failure. Journal of the American College of Cardiology, 70(19), 2378-2388. https://doi.org/10.1016/j.jacc.2017.09.026
  52. Sharma, A., Demissei, B. G., Tromp, J., Hillege, H. L., Cleland, J. G., O'Connor, C. M., ... Voors, A. A. (2017). A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure. European Journal of Heart Failure, 19(10), 1310-1320. https://doi.org/10.1002/ejhf.912
  53. Ferreira, J. P., Rossignol, P., Machu, J-L., Sharma, A., Girerd, N., Anker, S. D., ... Zannad, F. (2017). Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: Findings from BIOSTAT-CHF. European Journal of Heart Failure, 19(10), 1284-1293. https://doi.org/10.1002/ejhf.900
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