prof. dr. J.L. (Hans) Hillege

Cardiology

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E-mail:
h.hillege umcg.nl

Research

  1. 2020
  2. Brankovic, M., Akkerhuis, K. M., Hoorn, E. J., van Boven, N., van den Berge, J. C., Constantinescu, A., Brugts, J., van Ramshorst, J., Germans, T., Hillege, H., Boersma, E., Umans, V., & Kardys, I. (2020). Renal tubular damage and worsening renal function in chronic heart failure: Clinical determinants and relation to prognosis (Bio-SHiFT study). Clinical Cardiology, 43(6), 630-638. https://doi.org/10.1002/clc.23359
  3. ter Maaten, J. M., Martens, P., Damman, K., Dickstein, K., Ponikowski, P., Lang, C. C., Ng, L. L., Anker, S. D., Samani, N. J., Filippatos, G., Cleland, J. G., Zannad, F., Hillege, H. L., van Veldhuisen, D. J., Metra, M., Voors, A. A., & Mullens, W. (2020). Higher doses of loop diuretics limit uptitration of angiotensin-converting enzyme inhibitors in patients with heart failure and reduced ejection fraction. Clinical Research in Cardiology, (8), 1048-1059. https://doi.org/10.1007/s00392-020-01598-w
  4. 2019
  5. Whitty, J. A., de Bekker-Grob, E. W., Cook, N. S., Terris-Prestholt, F., Drummond, M., Falchetto, R., & Hillege, H. L. (2019). Patient Preferences in the Medical Product Lifecycle. Patient-Patient: centered outcomes research. https://doi.org/10.1007/s40271-019-00400-y
  6. van den Berg, M. E., Rijnbeek, P. R., Niemeijer, M. N., Hofman, A., van Herpen, G., Bots, M. L., Hillege, H., Swenne, C. A., Eijgelsheim, M., Stricker, B. H., & Kors, J. A. (2019). Corrigendum: Normal Values of Corrected Heart-Rate Variability in 10-Second Electrocardiograms for All Ages. Frontiers in Physiology, 10, [1373]. https://doi.org/10.3389/fphys.2019.01373
  7. ASIAN-HF Investigators, Santema, B. T., Ouwerkerk, W., Tromp, J., Sama, I. E., Ravera, A., Regitz-Zagrosek, V., Hillege, H., Samani, N. J., Zannad, F., Dickstein, K., Lang, C. C., Cleland, J. G., Ter Maaten, J. M., Metra, M., Anker, S. D., van der Harst, P., Ng, L. L., van der Meer, P., ... Voors, A. A. (2019). Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study. The Lancet, 394(10205), 1254-1263. https://doi.org/10.1016/S0140-6736(19)31792-1
  8. van den Berg, M. E., Kors, J. A., van Herpen, G., Bots, M. L., Hillege, H., Swenne, C. A., Stricker, B. H., & Rijnbeek, P. R. (2019). Normal Values of QT Variability in 10-s Electrocardiograms for all Ages. Frontiers in Physiology, 10, [1272]. https://doi.org/10.3389/fphys.2019.01272
  9. Markousis-Mavrogenis, G., Tromp, J., Ouwerkerk, W., Devalaraja, M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., van der Harst, P., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., Zannad, F., Zwinderman, A. H., Hillege, H. L., van Veldhuisen, D. J., Kakkar, R., ... van der Meer, P. (2019). The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study. European Journal of Heart Failure, 21(8), 965-973. https://doi.org/10.1002/ejhf.1482
  10. Suzuki, T., Yazaki, Y., Voors, A. A., Jones, D. J. L., Chan, D. C. S., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., & Ng, L. L. (2019). Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure: results from BIOSTAT-CHF. European Journal of Heart Failure, 21(7), 877-886. https://doi.org/10.1002/ejhf.1338
  11. Makady, A., van Veelen, A., de Boer, A., Hillege, H., Klungel, O. H., & Goettsch, W. (2019). Implementing managed entry agreements in practice: The Dutch reality check. Health Policy, 123(3), 267-274. https://doi.org/10.1016/j.healthpol.2018.09.016
  12. Ferreira, J. P., Metra, M., Mordi, I., Gregson, J., ter Maaten, J. M., Tromp, J., Anker, S. D., Dickstein, K., Hillege, H. L., Ng, L. L., van Veldhuisen, D. J., Lang, C. C., Voors, A. A., & Zannad, F. (2019). Heart failure in the outpatient versus inpatient setting: Findings from the BIOSTAT-CHF study. European Journal of Heart Failure, 21(1), 112-120. https://doi.org/10.1002/ejhf.1323
  13. 2018
  14. Tromp, J., Ouwerkerk, W., Demissei, B. G., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Voors, A. A., & van der Meer, P. (2018). Novel endotypes in heart failure: effects on guideline-directed medical therapy. European Heart Journal, 39(48), 4269-4276. https://doi.org/10.1093/eurheartj/ehy712
  15. Streng, K. W., Nauta, J. F., Hillege, H. L., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Zannad, F., Damman, K., van der Meer, P., & Voors, A. A. (2018). Non-cardiac comorbidities in heart failure with reduced, mid-range and preserved ejection fraction. International Journal of Cardiology, 271, 132-139. https://doi.org/10.1016/j.ijcard.2018.04.001
  16. Santema, B. T., Kloosterman, M., Van Gelder, I. C., Mordi, I., Lang, C. C., Lam, C. S. P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Van der Harst, P., Hillege, H. L., Ter Maaten, J. M., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zwinderman, A. H., ... Voors, A. A. (2018). Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction. European Heart Journal, 39(43), 3867-3875. https://doi.org/10.1093/eurheartj/ehy421
  17. Thong Huy Cao, Jones, D. J. L., Quinn, P. A., Chan, D. C. S., Hafid, N., Parry, H. M., Mohan, M., Sandhu, J. K., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., ... Ng, L. L. (2018). Using matrix assisted laser desorption ionisation mass spectrometry (MALDI-MS) profiling in order to predict clinical outcomes of patients with heart failure. Clinical proteomics, 15, [35]. https://doi.org/10.1186/s12014-018-9213-1
  18. Streng, K. W., Voors, A. A., Hillege, H. L., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Zannad, F., Damman, K., van der Meer, P., & Lang, C. C. (2018). Waist-to-hip ratio and mortality in heart failure. European Journal of Heart Failure, 20(9), 1269-1277. https://doi.org/10.1002/ejhf.1244
  19. Savji, N., Meijers, W. C., Bartz, T. M., Bhambhani, V., Cushman, M., Nayor, M., Kizer, J. R., Sarma, A., Blaha, M. J., Gansevoort, R. T., Gardin, J. M., Hillege, H. L., Ji, F., Kop, W. J., Lau, E. S., Lee, D. S., Sadreyev, R., van Gilst, W. H., Wang, T. J., ... Ho, J. E. (2018). The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF. JACC. Heart failure, 6(8), 701-709. https://doi.org/10.1016/j.jchf.2018.05.018
  20. Lycholip, E., Aamodt, I. T., Lie, I., Simbelyte, T., Puronaite, R., Hillege, H., de Vries, A., Kraai, I., Stromberg, A., Jaarsma, T., & Celutkiene, J. (2018). The dynamics of self-care in the course of heart failure management: Data from the IN TOUCH study. Patient Preference and Adherence, 12, 1113-1122. https://doi.org/10.2147/PPA.S162219
  21. Beusekamp, J. C., Tromp, J., van der Wal, H. H., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Rossignol, P., Zannad, F., Voors, A. A., & van der Meer, P. (2018). Potassium and the use of renin-angiotensin-aldosterone system inhibitors in heart failure with reduced ejection fraction: data from BIOSTAT-CHF. European Journal of Heart Failure, 20(5), 923-930. https://doi.org/10.1002/ejhf.1079
  22. van den Berg, M. E., Rijnbeek, P. R., Niemeijer, M. N., Hofman, A., van Herpen, G., Bots, M. L., Hillege, H., Swenne, C. A., Eijgelsheim, M., Stricker, B. H., & Kors, J. A. (2018). Normal Values of Corrected Heart-Rate Variability in 10-Second Electrocardiograms for All Ages. Frontiers in Physiology, 9, [424]. https://doi.org/10.3389/fphys.2018.00424
  23. Ferreira, J. P., Rossignol, P., Demissei, B., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., & Zannad, F. (2018). Coronary angiography in worsening heart failure: Determinants, findings and prognostic implications. Heart, 104(7), 606-613. https://doi.org/10.1136/heartjnl-2017-311750
  24. Brankovic, M., Akkerhuis, K. M., van Boven, N., Anroedh, S., Constantinescu, A., Caliskan, K., Manintveld, O., Cornel, J. H., Baart, S., Rizopoulos, D., Hillege, H., Boersma, E., Umans, V., & Kardys, I. (2018). Patient-specific evolution of renal function in chronic heart failure patients dynamically predicts clinical outcome in the Bio-SHiFT study. Kidney International, 93(4), 952-960. https://doi.org/10.1016/j.kint.2017.09.013
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