prof. dr. H.J. (Henkjan) Verkade
Professor of Pediatrics - Gastroenterology/Hepatology

Research
1 - 50 out of 308Page size: 50
- 2021
- Li, Y., Nieuwenhuis, L. M., Voskuil, M. D., Gacesa, R., Hu, S., Jansen, B. H., Uniken Venema, W. T., Hepkema, B. G., Blokzijl, H., Verkade, H. J., Lisman, T., Weersma, R. K., Porte, R. J., Festen, E. A. M., & de Meijer, V. E. (2021). Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study. American Journal of Transplantation. https://doi.org/10.1111/ajt.16490
- 2020
- Nomden, M., Beljaars, L., Verkade, H. J., Hulscher, J. B. F., & Olinga, P. (2020). Current Concepts of Biliary Atresia and Matrix Metalloproteinase-7: A Review of Literature. Frontiers in Medicine, 7, [617261]. https://doi.org/10.3389/fmed.2020.617261
- Rodijk, L. H., Bos, A. F., Verkade, H. J., de Kleine, R. H., Hulscher, J. B. F., & Bruggink, J. L. M. (2020). Early Motor Repertoire in Infants with Biliary Atresia: A Nationwide Prospective Cohort Study. Journal of Pediatric Gastroenterology and Nutrition, Publish Ahead of Print. https://doi.org/10.1097/MPG.0000000000003021
- Weghorst, A., Holtman, G., Wolters, P. I., Russchen, H., Fickweiler, F., Verkade, H., Post, J., Vermeulen, K., Kollen, B., Bonvanie, I., & Berger, M. (2020). Recommendations for clinical research in children presenting to primary care out-of-hours services. BJGP open. https://doi.org/10.3399/bjgpopen20X101154
- Kunst, R. F., Verkade, H. J., Oude Elferink, R. P. J., & van de Graaf, S. F. J. (2020). Targeting the four pillars of enterohepatic bile salt cycling; lessons from genetics and pharmacology. Hepatology. https://doi.org/10.1002/hep.31651
- van de Peppel, I. P., Rao, A., Dommerholt, M. B., Bongiovanni, L., Thomas, R., de Bruin, A., Karpen, S. J., Dawson, P. A., Verkade, H. J., & Jonker, J. W. (2020). The Beneficial Effects of Apical Sodium-Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition. Molecular Nutrition & Food Research, (24), [e2000750]. https://doi.org/10.1002/mnfr.202000750
- van der Schoor, L. W. E., van Faassen, M. H. J. R., Kema, I., Baptist, D. H., Olthuis, A. J., Jonker, J. W., Verkade, H. J., Groen, H., & Hulzebos, C. V. (2020). Blue LED phototherapy in preterm infants: effects on an oxidative marker of DNA damage. ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 105(6), 628-633. https://doi.org/10.1136/archdischild-2019-317024
- Rodijk, L. H., Schins, E. M. W., Witvliet, M. J., Alizadeh, B. Z., Verkade, H. J., de Kleine, R. H., Hulscher, J. B. F., & Bruggink, J. L. M. (2020). Quality of Life in Parents of Children With Biliary Atresia. Journal of Pediatric Gastroenterology and Nutrition, 71(5), 641-646. https://doi.org/10.1097/MPG.0000000000002858
- Bertolini, A., van de Peppel, I. P., Bodewes, F. A. J. A., Moshage, H., Fantin, A., Farinati, F., Fiorotto, R., Jonker, J. W., Strazzabosco, M., Verkade, H. J., & Peserico, G. (2020). Abnormal Liver Function Tests in Patients WithCOVID-19: Relevance and Potential Pathogenesis. Hepatology. https://doi.org/10.1002/hep.31480
- Roscam Abbing, R. L. P., Kuipers, F., Paulusma, C. C., Verkade, H. J., Groen, A. K., Oude Elferink, R. P. J., van, S. F. J., & de Graaf, I. M. (2020). Reply to Letter to the Editor HEP-20-0593. Hepatology. https://doi.org/10.1002/hep.31291
- Grutters, L. A., Pennings, J. P., Bruggink, J. L. M., Viddeleer, A. R., Verkade, H. J., de Kleine, R. H. J., & de Haas, R. J. (2020). Body Composition of Infants With Biliary Atresia: Anthropometric Measurements and Computed Tomography-based Body Metrics. Journal of Pediatric Gastroenterology and Nutrition, 71(4), 440-445. https://doi.org/10.1097/MPG.0000000000002859
- Ronda, O. A. H. O., van de Heijning, B. J. M., Martini, I., Gerding, A., Wolters, J. C., van der Veen, Y. T., Koehorst, M., Jurdzinski, A., Havinga, R., van der Beek, E. M., Kuipers, F., & Verkade, H. J. (2020). Effects of an early life diet containing large phospholipid-coated lipid globules on hepatic lipid metabolism in mice. Scientific Reports, 10(1), [16128]. https://doi.org/10.1038/s41598-020-72777-y
- Ronda, O. A. H. O., van de Heijning, B. J. M., de Bruin, A., Thomas, R. E., Martini, I., Koehorst, M., Gerding, A., Koster, M. H., Bloks, V. W., Jurdzinski, A., Mulder, N. L., Havinga, R., van der Beek, E. M., Reijngoud, D-J., Kuipers, F., & Verkade, H. J. (2020). Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet. PLoS ONE, 15(9), e0232069. [0232069]. https://doi.org/10.1371/journal.pone.0232069
- Nomden, M., van Wessel, D. B. E., Ioannou, S., Verkade, H. J., de Kleine, R. H., Alizadeh, B. Z., Bruggink, J. L. M., & Hulscher, J. B. F. (2020). A Higher Incidence of Isolated Biliary Atresia in Rural Areas: Results from an Epidemiological Study in The Netherlands. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/MPG.0000000000002916
- Kamath, B. M., Stein, P., Houwen, R. H. J., & Verkade, H. J. (2020). Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis. Liver International, 40(8), 1812-1822. https://doi.org/10.1111/liv.14553
- Verkade, H. J., Thompson, R. J., Arnell, H., Fischler, B., Gillberg, P-G., Mattsson, J. P., Torfgård, K., & Lindström, E. (2020). Systematic Review and Meta-Analysis: Partial External Biliary Diversion in Progressive Familial Intrahepatic Cholestasis. Journal of Pediatric Gastroenterology and Nutrition, 71(2), 176-183. https://doi.org/10.1097/MPG.0000000000002789
- CACATU consortium, Van de Vijver, E., Heida, A., Ioannou, S., Van Biervliet, S., Hummel, T., Yuksel, Z., Gonera-de Jong, G., Schulenberg, R., Muller Kobold, A., Verkade, H. J., & van Rheenen, P. F. (2020). Test Strategies to Predict Inflammatory Bowel Disease Among Children With Nonbloody Diarrhea. Pediatrics, 146(2), [e20192235]. https://doi.org/10.1542/peds.2019-2235
- Rodijk, L. H., Schins, E. M. W., Witvliet, M. J., Verkade, H. J., de Kleine, R. H., Hulscher, J. B. F., & Bruggink, J. L. M. (2020). Health-Related Quality of Life in Biliary Atresia Patients with Native Liver or Transplantation. European Journal of Pediatric Surgery, 30(3), 261-272. https://doi.org/10.1055/s-0040-1712932
- Ronda, O. A. H. O., van de Heijning, B. J. M., Martini, I. A., Koehorst, M., Havinga, R., Jurdzinski, A., Bloks, V. W., van Dijk, T. H., van der Beek, E. M., Kuipers, F., & Verkade, H. J. (2020). An early-life diet containing large phospholipid-coated lipid globules programs later-life postabsorptive lipid trafficking in high-fat diet but not in low-fat dietfed mice. British Journal of Nutrition, 1-25. https://doi.org/10.1017/S0007114520002421
- van Wessel, D. B. E., Thompson, R. J., Gonzales, E., Jankowska, I., Sokal, E., Grammatikopoulos, T., Kadaristiana, A., Jacquemin, E., Spraul, A., Lipiński, P., Czubkowski, P., Rock, N., Shagrani, M., Broering, D., Algoufi, T., Mazhar, N., Nicastro, E., Kelly, D., Nebbia, G., ... Verkade, H. J. (2020). Genotype correlates with the natural history of severe bile salt export pump deficiency. Journal of Hepatology, 73(1), 84-93. https://doi.org/10.1016/j.jhep.2020.02.007
- Mistry, R. H., Liu, F., Borewicz, K., Lohuis, M. A. M., Smidt, H., Verkade, H. J., & Tietge, U. J. F. (2020). Long-Term beta-galacto-oligosaccharides Supplementation Decreases the Development of Obesity and Insulin Resistance in Mice Fed a Western-Type Diet. Molecular Nutrition & Food Research, 64(12), [1900922]. https://doi.org/10.1002/mnfr.201900922
- Mistry, R. H., Borewicz, K., Gu, F., Verkade, H. J., Schols, H. A., Smidt, H., & Tietge, U. J. F. (2020). Dietary Isomalto/Malto-Polysaccharides Increase Fecal Bulk and Microbial Fermentation in Mice. Molecular Nutrition & Food Research, 64(12), e2000251. [2000251]. https://doi.org/10.1002/mnfr.202000251
- Blankestijn, M., van de Peppel, I. P., Dvorak, A., Capkova, N., Vitek, L., Jonker, J. W., & Verkade, H. J. (2020). Induction of fecal cholesterol excretion is not effective for the treatment of hyperbilirubinemia in Gunn rats. Pediatric Research. https://doi.org/10.1038/s41390-020-0926-2
- Indolfi, G., Abdel-Hady, M., Bansal, S., Debray, D., Smets, F., Czubkowski, P., van der Woerd, W., Samyn, M., Jahnel, J., Gupte, G., Zellos, A., Mozer-Glassberg, Y., Verkade, H. J., Sokal, E., & Fischler, B. (2020). Management of Hepatitis B Virus Infection and Prevention of Hepatitis B Virus Reactivation in Children With Acquired Immunodeficiencies or Undergoing Immune Suppressive, Cytotoxic, or Biological Modifier Therapies. Journal of Pediatric Gastroenterology and Nutrition, 70(4), 527-538. https://doi.org/10.1097/MPG.0000000000002628
- Werner, M. J. M., de Kleine, R. H. J., de Boer, M. T., de Meijer, V. E., Scheenstra, R., Verkade, H. J., Bodewes, F. A. J. A., Bontemps, S. T. H., Reyntjens, K. M. E. M., Dikkers, R., Lisman, T., & Porte, R. J. (2020). Routine Postoperative Antithrombotic Therapy in Pediatric Liver Transplantation: Impact on Bleeding and Thrombotic Complications. Thrombosis and Haemostasis, 120(4), 627-637. https://doi.org/10.1055/s-0039-1701010
- Warmink-Perdijk, W. D. B., Peters, L. L., Tigchelaar, E. F., Dekens, J. A. M., Jankipersadsing, S. A., Zhernakova, A., Bossers, W. J. R., Sikkema, J., de Jonge, A., Reijneveld, S. A., Verkade, H. J., Koppelman, G. H., Wijmenga, C., Kuipers, F., & Scherjon, S. A. (2020). Lifelines NEXT: a prospective birth cohort adding the next generation to the three-generation Lifelines cohort study. European Journal of Epidemiology, 35(2), 157-168. https://doi.org/10.1007/s10654-020-00614-7
- Rodijk, L. H., den Heijer, A. E., Hulscher, J. B. F., Alizadeh, B. Z., de Kleine, R. H. J., Verkade, H. J., & Bruggink, J. L. M. (2020). Long-Term Neurodevelopmental Outcomes in Children with Biliary Atresia. Journal of Pediatrics, 217, 118-+. https://doi.org/10.1016/j.jpeds.2019.10.054
- Rodijk, L., Heijer, den, A., Hulscher, J. B. F., Ziad Alizadeh, B., Kleine, de, R., Verkade, H., & Bruggink, J. (2020). Long-Term Neurodevelopmental Outcomes in Children with Biliary Atresia. The Journal of Pediatrics, 217, 118-124.e3. https://doi.org/10.1016/j.jpeds.2019.10.054
- Ikpa, P. T., Doktorova, M., Meijsen, K. F., Nieuwenhuijze, N. D. A., Verkade, H. J., Jonker, J. W., de Jonge, H. R., & Bijvelds, M. J. C. (2020). Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice. Cellular and molecular gastroenterology and hepatology, 9(1), 47-60. https://doi.org/10.1016/j.jcmgh.2019.08.006
- Dimova, L. G., Battista, S., Plosch, T., Kampen, R. A., Liu, F., Verkaik-Schakel, R. N., Pratico, D., Verkade, H. J., & Tietge, U. J. F. (2020). Gestational oxidative stress protects against adult obesity and insulin resistance. Redox Biology, 28, [101329]. https://doi.org/10.1016/j.redox.2019.101329
- Nomden, M., Beljaars, L., Verkade, H. J., Hulscher, J. B. F., & Olinga, P. (2020). Current Concepts of Biliary Atresia and Matrix Metalloproteinase-7: A Review of Literature. Frontiers in Medicine, 7, 617261. https://doi.org/10.3389/fmed.2020.617261
- 2019
- Ronda, O. A. H. O., van de Heijning, B. J. M., de Bruin, A., Jurdzinski, A., Kuipers, F., & Verkade, H. J. (2019). Programming effects of an early-life diet containing large phospholipid-coated lipid globules are transient under continuous exposure to a high-fat diet. British Journal of Nutrition, 122(12), 1321-1328. https://doi.org/10.1017/S0007114519002083
- Hoogerland, J. A., Lei, Y., Wolters, J. C., de Boer, J. F., Bos, T., Bleeker, A., Mulder, N. L., van Dijk, T. H., Kuivenhoven, J. A., Rajas, F., Mithieux, G., Haeusler, R. A., Verkade, H. J., Bloks, V. W., Kuipers, F., & Oosterveer, M. H. (2019). Glucose-6-phosphate regulates hepatic bile acid synthesis in mice. Hepatology, 70(6), 2171-2184. https://doi.org/10.1002/hep.30778
- Nieuwenhuis, L., Werner, M., Van Son, J., De Kleine, R., Scheenstra, R., Verkade, H., Porte, R., & deMeijer, V. (2019). DONOR AGE DOES NOT NECESSARILY IMPACT LONG-TERM SURVIVAL AFTER PEDIATRIC SPLIT LIVER TRANSPLANTATION. Transplant International, 32, 9.
- NAPPED Natural Course Prognosis (2019). Genotype-phenotype relationships in patients with relatively mild mutations in abcb11: Results from the napped consortium. Hepatology, 70, 48A-49A.
- Verstegen, M., Roos, F., Burka, K., Gehart, H., Jager, M., de Wolf, M., Fuchs, S., Verkade, H., Roest, H., IJzermans, J., Cuppen, E., & van der Laan, L. (2019). HUMAN EXTRA HEPATIC BILE DUCT-DERIVED ORGANOIDS FOR STEM CELL CHARACTERIZATION AND DISEASE MODELING. Transplant International, 32, 5.
- Verkade, H. J., Van der Vlist, C. J., Van den Berg, A. P., Porte, R. J., Metselaar, H. J., Van Hoek, B., Verbeek, J. P. H. M., Beuers, U., Van Rheenen, P. F., & Besouw, M. T. P. (2019). RENAL FUNCTION AFTER LIVER TRANSPLANTATION AT PAEDIATRIC AGE: EFFECTS OF LONG-TERM CALCINEURIN INHIBITOR TREATMENT AND OF ITS EARLY WITHDRAWAL. Hepatology, 70, 477A-477A.
- Haisma, S-M., Verkade, H., Scheenstra, R., van der Doef, H. P. J., Bodewes, F. A. J. A., & van Rheenen, P. F. (2019). Time-to-reach Target Calprotectin Level in Newly Diagnosed Patients With Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition, 69(4), 466-473. https://doi.org/10.1097/MPG.0000000000002458
- van de Peppel, I. P., Bertolini, A., van Dijk, T. H., Groen, A. K., Jonker, J. W., & Verkade, H. J. (2019). Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice[S]. Journal of Lipid Research, 60(9), 1562-1572. https://doi.org/10.1194/jlr.M094607
- Matton, A. P. M., de Vries, Y., van Leeuwen, O. B., Burlage, L. C., van Rijn, R., Fujiyoshi, M., de Meijer, V. E., Ubbink, R., Pelgrim, G. J., Werner, M. J. M., Reyntjens, K., van den Berg, A. P., de Boer, M. T., de Kleine, R. H. J., Verkade, H. J., Gouw, A. S. H., Lisman, T., & Porte, R. J. (2019). Biliary bicarbonate, pH and glucose are suitable biomarkers of biliary viability during ex situ normothermic machine perfusion of human donor livers. Transplantation, 103(8), 234.
- Rodijk, L. H., den Heijer, A. E., Hulscher, J. B. F., Verkade, H. J., de Kleine, R. H. J., & Bruggink, J. L. M. (2019). Long-term neurodevelopmental outcomes in children with biliary atresia. Transplantation, 103(8), 82.
- Werner, M. J. M., de Kleine, R. H. J., de Boer, M. T., de Meijer, V. E., Scheenstra, R., Verkade, H. J., Bodewes, F. A. J. A., Bontemps, S. T. H., Reyntjens, K. M. E. M., Dikkers, R., Lisman, T., & Porte, R. J. (2019). Risk factors for thrombosis and bleeding in ppediatric liver transplantation in an era of routine postoperative antithrombotic therapy. Transplantation, 103(8), 371-372.
- Matton, A. P. M., de Vries, Y., Burlage, L. C., van Rijn, R., Fujiyoshi, M., de Meijer, V. E., de Boer, M. T., de Kleine, R. H. J., Verkade, H. J., Gouw, A. S. H., Lisman, T., & Porte, R. J. (2019). Biliary Bicarbonate, pH, and Glucose Are Suitable Biomarkers of Biliary Viability During Ex Situ Normothermic Machine Perfusion of Human Donor Livers. Transplantation, 103(7), 1405-1413. https://doi.org/10.1097/TP.0000000000002500
- Zwarts, I., van Zutphen, T., Kruit, J. K., Liu, W., Oosterveer, M. H., Verkade, H. J., Uhlenhaut, N. H., & Jonker, J. W. (2019). Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR. Scientific Reports, 9(1), [9299]. https://doi.org/10.1038/s41598-019-45803-x
- van der Schoor, L. W. E., Hulzebos, C. V., van Faassen, M. H., Kema, I. P., de Bruin, A., Havinga, R., Koster, M., Youssef, S. A., Bongiovanni, L., Jonker, J. W., & Verkade, H. J. (2019). LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats. Pediatric Research, 85(7), 1041-1047. https://doi.org/10.1038/s41390-019-0367-y
- Van der Vlist, C., Van den Berg, A. P., Porte, R. J., Metselaar, H. J., Van Hoek, B., Beuers, U. H., Van Rheenen, P. F., Verkade, H. J., & Besouw, M. T. P. (2019). Renal function after liver transplantation at paediatric age: Effects of long-term calcineurin inhibitor treatment. Nephrology Dialysis Transplantation, 34, 462.
- Ronda, O., Havinga, H., van de Heijning, B. J. M., Kuipers, F., & Verkade, H. (2019). Relationship between liver size and liver function in mice. Journal of Pediatric Gastroenterology and Nutrition, 68, 750.
ID: 158171