prof. dr. H.H. (Harm H) Kampinga

Hoogleraar

Research

  1. 2018
  2. Ast, A., Buntru, A., Schindler, F., Hasenkopf, R., Schulz, A., Brusendorf, L., ... Wanker, E. E. (2018). mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease. Molecular Cell, 71(5), 675-688.e6. DOI: 10.1016/j.molcel.2018.07.032
  3. 2017
  4. Carra, S., Alberti, S., Arrigo, P. A., Benesch, J. L., Benjamin, I. J., Boelens, W., ... Tanguay, R. M. (2017). The growing world of small heat shock proteins: From structure to functions. Cell stress & chaperones, 22(4), 601-611. DOI: 10.1007/s12192-017-0787-8
  5. 2016
  6. 2015
  7. Smeets, C. J. L. M., Jezierska, J., Watanabe, H., Duarri Pique, A., Fokkens, M. R., Meijer, M., ... Verbeek, D. S. (2015). Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23. Brain, 138, 2537-2552. DOI: 10.1093/brain/awv195
  8. Meijering, R. A. M., Wiersma, M., van Marion, D. M. S., Zhang, D., Hoogstra-Berends, F., Dijkhuis, A-J., ... Brundel, B. J. J. M. (2015). RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response. PLoS ONE, 10(7), [e0133553]. DOI: 10.1371/journal.pone.0133553
  9. 2014
  10. Minoia, M., Boncoraglio, A., Vinet, J., Morelli, F. F., Brunsting, J. F., Poletti, A., ... Carra, S. (2014). BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: Implications for a proteasome-to-autophagy switch. Autophagy, 10(9), 1603-1621. DOI: 10.4161/auto.29409
  11. 2013
  12. Gillis, J., Schipper-Krom, S., Juenemann, K., Gruber, A., Coolen, S., van den Nieuwendijk, R., ... Reits, E. A. (2013). The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides. The Journal of Biological Chemistry, 288(24), 17225-17237. DOI: 10.1074/jbc.M112.421685
  13. Crul, T., Toth, N., Piotto, S., Literati-Nagy, P., Tory, K., Haldimann, P., ... Vigh, L. (2013). Hydroximic Acid Derivatives: Pleiotropic Hsp Co-Inducers Restoring Homeostasis and Robustness. Current Pharmaceutical Design, 19(3), 309-346.
  14. 2012
  15. Heldens, L., van Genesen, S. T., Hanssen, L. L. P., Hageman, J., Kampinga, H. H., & Lubsen, N. H. (2012). Protein refolding in peroxisomes is dependent upon an HSF1-regulated function. Cell stress & chaperones, 17(5), 603-613. DOI: 10.1007/s12192-012-0335-5
  16. Nishizawa, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Tamura, Y., Mori, T., ... Sato, N. (2012). HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem-like Cells. Cancer Research, 72(11), 2844-2854. DOI: 10.1158/0008-5472.CAN-11-3062
  17. Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., ... Zuckerbraun, B. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4), 445-544.
  18. Hoogstra-Berends, F., Meijering, R. A. M., Zhang, D., Heeres, A., Loen, L., Seerden, J-P., ... Brundel, B. J. J. M. (2012). Heat Shock Protein-Inducing Compounds as Therapeutics to Restore Proteostasis in Atrial Fibrillation. TRENDS IN CARDIOVASCULAR MEDICINE, 22(3), 62-68. [PII S1050-1738(12)00206-X]. DOI: 10.1016/j.tcm.2012.06.013
  19. 2011
  20. Yang, J., Zhao, Y., Ma, K., Jiang, F-J., Liao, W., Zhang, P., ... Zhu, W-G. (2011). Deficiency of hepatocystin induces autophagy through an mTOR-dependent pathway. Autophagy, 7(7), 748-759. DOI: 10.4161/auto.7.7.15822
  21. Ke, L., Meijering, R. A. M., Hoogstra-Berends, F., Mackovicova, K., Vos, M. J., Van Gelder, I. C., ... Brundel, B. J. J. M. (2011). HSPB1, HSPB6, HSPB7 and HSPB8 Protect against RhoA GTPase-Induced Remodeling in Tachypaced Atrial Myocytes. PLoS ONE, 6(6), [20395]. DOI: 10.1371/journal.pone.0020395
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