prof. dr. G.M.M. (Geny) Groothuis

Professor

prof. dr. G.M.M. (Geny) Groothuis
Telephone:
+31 50 36 33273 (0503633272 (secretary))
E-mail:
g.m.m.groothuis rug.nl

Research

Postal address:
A Deusinglaan
1
Groningen
Netherlands
Phone: +31 50 363 3272Fax: +31 50 363 3247
  1. 2019
  2. 2018
  3. Luangmonkong, T., Suriguga, S., Mutsaers, H. A. M., Groothuis, G. M. M., Olinga, P., & Boersema, M. (2018). Targeting Oxidative Stress for the Treatment of Liver Fibrosis. In B. Nilius, P. DeTombe, T. Gudermann, R. Jahn, & R. Lill (Eds.), Reviews of Physiology, Biochemistry and Pharmacology (pp. 71-102). (Reviews of Physiology Biochemistry and Pharmacology; Vol. 175). Cham: Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/112_2018_10
  4. 2017
  5. Spreckelmeyer, S., Estrada Ortiz, N., Prins, G., van der Zee, M., Gammelgaard, B., Sturup, S., ... Casini, A. (2017). On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent. Metallomics, 9, 1786-1795. https://doi.org/10.1039/c7mt00271h
  6. 2016
  7. Johnson, M., Kozielska, M., Pilla Reddy, V., Vermeulen, A., Barton, H. A., Grimwood, S., ... Proost, J. H. (2016). Erratum to: Translational Modeling in Schizophrenia: Predicting Human Dopamine D₂ Receptor Occupancy. Pharmaceutical Research, 33(5), 1305-1306. https://doi.org/10.1007/s11095-016-1888-2
  8. 2015
  9. Oomen, P., Skolimowski, M., Groothuis, G., & Verpoorte, E. (2015). Design of a microfluidic system for measurement of oxygen consumption by tissue slices. In 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS) (pp. 1722-1724)
  10. Verpoorte, E., Oomen, P., Skolimowski, M., Mulder, P., van Midwoud, P., Starokozhko, V., ... Groothuis, G. (2015). How microtechnologies enable organs-on-a-chip. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems: Proceedings of a meeting held 21-25 June 2015, Anchorage, Alaska, USA Institute of Electrical and Electronics Engineers (IEEE).
  11. Daum, S., Chekhun, V. F., Todor, I. N., Lukianova, N. Y., Shvets, Y. V., Sellner, L., ... Mokhir, A. (2015). Improved Synthesis of N-Benzylaminoferrocene-Based Prodrugs and Evaluation of Their Toxicity and Antileukemic Activity. Journal of Medicinal Chemistry, 58(4), 2015-2024. https://doi.org/10.1021/jm5019548
  12. Groothuis, G. (2015). Application of human tissue for toxicity testing of metallodrugs. 1st International Symposium on "Clinical and Experimental Metallodrugs in Medicine (CEMM): Cancer Chemotherapy", Honolulu, United States.
  13. Evers, B., Li, M., de Jager, M., de Graaf, I., & Groothuis, G. (2015). Communicating the ex vivo study on the activity of the apical sodium-dependent bile acid transporter in precision-cut intestinal slices. Poster session presented at The 2015 annual meeting of the Netherlands Society of Toxicology - Nederlandse Vereniging voor Toxicologie (NVT) and NVT PhD days, Soesterberg, Netherlands.
  14. Soliman, N., Starokozhko, V., de Graaf, I., & Groothuis, G. (2015). PCLS as a model to study drug-induced cholestasis. 39-39. Poster session presented at The 2015 annual meeting of the Netherlands Society of Toxicology - Nederlandse Vereniging voor Toxicologie (NVT) and NVT PhD days, Soesterberg, Netherlands.
  15. Li, M., Vokral, I., de Graaf, I., de Jager, M., Evers, B., & Groothuis, G. (2015). Precision-cut intestinal slices as ex vivo model to study the uptake of bile acids by ASBT in the intestine. 37. Abstract from 13th European ISSX (International Society for the Study of Xenobiotics) Meeting, Glasgow, United Kingdom.
  16. Starokozhko, V., & Groothuis, G. (2015). Species-specific effects of incubation media on precision-cut liver slices cultured in vitro. Poster session presented at The 2015 annual meeting of the Netherlands Society of Toxicology - Nederlandse Vereniging voor Toxicologie (NVT) and NVT PhD days, Soesterberg, Netherlands.
  17. Groothuis, G., Casini, A., Meurs, H., & Olinga, P. (2015). Translational research in pharmacology and toxicology using precision-cut tissue slices. In R. Coleman (Ed.), Human-based Systems for Translational Research (pp. 38-65). Cambridge: RSC publishing. https://doi.org/10.1039/9781782620136-00038
  18. Quach, H. P., Hoi, S. Y., Bruinsma, A., Durk, M. R., Chow, E. C., Groothuis, G., & Pang, K. S. (2015). Vitamin D deficiency is a risk factor for hypercholesterolemia: Role of the vitamin D receptor in CYP7A1 activation and cholesterol lowering. Abstract from AAPS Annual Meeting and Exposition, Orlando, United States.
  19. 2014
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