D. Incarnato, PhD

D. Incarnato, PhD
E-mail:
d.incarnato rug.nl

Research

Research units:

Postal address:
Nijenborgh7
Gebouw
9747 AG
Groningen
Netherlands
Phone: +31 50 363 2103, +31 50 363 2103Fax: +31 50 363 2368
  1. 2020
  2. Zorzan, I., Pellegrini, M., Arboit, M., Incarnato, D., Maldotti, M., Forcato, M., Tagliazucchi, G. M., Carbognin, E., Montagner, M., Oliviero, S., & Martello, G. (2020). The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs. Nature Communications, 11(1), [2364]. https://doi.org/10.1038/s41467-020-16205-9
  3. Manfredonia, I., Nithin, C., Ponce-Salvatierra, A., Ghosh, P., Wirecki, T. K., Marinus, T., Ogando, N. S., Snijder, E. J., van Hemert, M. J., Bujnicki, J. M., & Incarnato, D. (2020). Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements. Nucleic Acids Research. https://doi.org/10.1093/nar/gkaa1053
  4. Di Timoteo, G., Dattilo, D., Centron-Broco, A., Colantoni, A., Guarnacci, M., Rossi, F., Incarnato, D., Oliviero, S., Fatica, A., Morlando, M., & Bozzoni, I. (2020). Modulation of circRNA Metabolism by m6A Modification. Cell reports, 31(6), [107641]. https://doi.org/10.1016/j.celrep.2020.107641
  5. 2019
  6. Managò, A., Audrito, V., Mazzola, F., Sorci, L., Gaudino, F., Gizzi, K., Vitale, N., Incarnato, D., Minazzato, G., Ianniello, A., Varriale, A., D'Auria, S., Mengozzi, G., Politano, G., Oliviero, S., Raffaelli, N., & Deaglio, S. (2019). Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation. Nature Communications, 10(1), [4116]. https://doi.org/10.1038/s41467-019-12055-2
  7. Simon, L. M., Morandi, E., Luganini, A., Gribaudo, G., Martinez-Sobrido, L., Turner, D. H., Oliviero, S., & Incarnato, D. (2019). In vivo analysis of influenza A mRNA secondary structures identifies critical regulatory motifs. Nucleic Acids Research, 47(13), 7003-7017. https://doi.org/10.1093/nar/gkz318
  8. Morandi, E., Cereda, M., Incarnato, D., Parlato, C., Basile, G., Anselmi, F., Lauria, A., Simon, L. M., Laurence Polignano, I., Arruga, F., Deaglio, S., Tirtei, E., Fagioli, F., & Oliviero, S. (2019). HaTSPiL: A modular pipeline for high-throughput sequencing data analysis. PLoS ONE, 14(10), [e0222512]. https://doi.org/10.1371/journal.pone.0222512
  9. 2018
  10. El Soury, M., Fornadari, B. E., Morano, M., Grazio, E., Ronchi, G., Incarnato, D., Giacobini, M., Geuna, S., Provero, P., & Gambarotta, G. (2018). Soluble Neuregulin1 Down-Regulates Myelination Genes in Schwann Cells. Frontiers in Molecular Neuroscience, 11, [157]. https://doi.org/10.3389/fnmol.2018.00157
  11. Brossa, A., Papadimitriou, E., Collino, F., Incarnato, D., Oliviero, S., Camussi, G., & Bussolati, B. (2018). Role of CD133 Molecule in Wnt Response and Renal Repair. Stem Cells Translational Medicine, 7(3), 283-294. https://doi.org/10.1002/sctm.17-0158
  12. Distasi, C., Ruffinatti, F. A., Dionisi, M., Antoniotti, S., Gilardino, A., Croci, G., Riva, B., Bassino, E., Alberto, G., Castrofiorio, E., Incarnato, D., Morandi, E., Martra, G., Oliviero, S., Munaron, L., & Lovisolo, D. (2018). SiO2 nanoparticles modulate the electrical activity of neuroendocrine cells without exerting genomic effects. Scientific Reports, 8, [2760]. https://doi.org/10.1038/s41598-018-21157-8
  13. 2017
  14. Incarnato, D., Morandi, E., Anselmi, F., Simon, L. M., Basile, G., & Oliviero, S. (2017). In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding. Nucleic Acids Research, 45(16), 9716-9725. [nar/gkx617]. https://doi.org/10.1093/nar/gkx617
  15. Avalle, L., Incarnato, D., Savino, A., Gai, M., Marino, F., Pensa, S., Barbieri, I., Stadler, M. B., Provero, P., Oliviero, S., & Poli, V. (2017). MicroRNAs-143 and -145 induce epithelial to mesenchymal transition and modulate the expression of junction proteins. Cell death and differentiation, 24, 1750-1760. https://doi.org/10.1177/1010428317691682
  16. Neri, F., Rapelli, S., Krepelova, A., Incarnato, D., Parlato, C., Basile, G., Maldotti, M., Anselmi, F., & Oliviero, S. (2017). Intragenic DNA methylation prevents spurious transcription initiation. Nature, 543(7643), 72-77. [nature21373]. https://doi.org/10.1038/nature21373
  17. Incarnato, D., Anselmi, F., Morandi, E., Neri, F., Maldotti, M., Rapelli, S., Parlato, C., Basile, G., & Oliviero, S. (2017). High-throughput single-base resolution mapping of RNA 2΄-O-methylated residues. Nucleic Acids Research, 45(3), 1433-1441. https://doi.org/10.1093/nar/gkw810
  18. Arruga, F., Gizdic, B., Bologna, C., Cisnetto, S., Buonincontri, R., Serra, S., Vaisitti, T., Gizzi, K., Vitale, N., Garaffo, G., Mereu, E., Diop, F., Neri, F., Incarnato, D., Coscia, M., Allan, J., Piva, R., Oliviero, S., Furman, R. R., ... Deaglio, S. (2017). Mutations in NOTCH1 PEST domain orchestrate CCL19-driven homing of chronic lymphocytic leukemia cells by modulating the tumor suppressor gene DUSP22. Leukemia, 31(9), 1882-1893. https://doi.org/10.1038/leu.2016.383
  19. 2016
  20. Maldotti, M., Incarnato, D., Neri, F., Krepelova, A., Rapelli, S., Anselmi, F., Parlato, C., Basile, G., Dettori, D., Calogero, R., & Oliviero, S. (2016). The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to regulate c-Myc expression. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1859(10), 1322-1332. https://doi.org/10.1016/j.bbagrm.2016.06.010
  21. 2015
  22. Neri, F., Incarnato, D., & Oliviero, S. (2015). DNA methylation and demethylation dynamics. Oncotarget, 6(33), 34049-34050. [oncotarget.6039]. https://doi.org/10.18632/oncotarget.6039
  23. Collino, F., Bruno, S., Incarnato, D., Dettori, D., Neri, F., Provero, P., Pornatto, M., Oliviero, S., Tetta, C., Quesenberry, P. J., & Camussi, G. (2015). AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs. Journal of the American Society of Nephrology, 26(10), 2349-2390. [ASN.2014070710]. https://doi.org/10.1681/ASN.2014070710
  24. Neri, F., Incarnato, D., Krepelova, A., Dettori, D., Rapelli, S., Maldotti, M., Parlato, C., Anselmi, F., Galvagni, F., & Oliviero, S. (2015). TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues. Nucleic Acids Research, 43(14), 6814-6826. [nar/gkv392]. https://doi.org/10.1093/nar/gkv392
  25. Neri, F., Incarnato, D., Krepelova, A., Rapelli, S., Anselmi, F., Parlato, C., Medana, C., Dal Bello, F., & Oliviero, S. (2015). Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics. Cell reports, 10(5), 674-683. https://doi.org/10.1016/j.celrep.2015.01.008
  26. Oudejans, C. B., Michel, O. J., Janssen, R., Habets, R., Poutsma, A., Sistermans, E. A., Weiss, M. M., Incarnato, D., Oliviero, S., Kleiverda, G., van Dijk, M., & Arngrimsson, R. (2015). Susceptibility allele-specific loss of miR-1324-mediated silencing of the INO80B chromatin-assembly complex gene in pre-eclampsia. Human Molecular Genetics, 24(1), 118-127. https://doi.org/10.1093/hmg/ddu423
  27. 2014
  28. 2013
  29. Neri, F., Krepelova, A., Incarnato, D., Maldotti, M., Parlato, C., Galvagni, F., Matarese, F., Stunnenberg, H. G., & Oliviero, S. (2013). Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs. Cell, 155(1), 121-134. https://doi.org/10.1016/j.cell.2013.08.056
  30. Evellin, S., Galvagni, F., Zippo, A., Neri, F., Orlandini, M., Incarnato, D., Dettori, D., Neubauer, S., Kessler, H., Wagner, E. F., & Oliviero, S. (2013). FOSL1 Controls the Assembly of Endothelial Cells into Capillary Tubes by Direct Repression of ﰀv and ﰁ3 Integrin Transcription. Molecular and Cellular Biology, 33(6), 1198-1209. https://doi.org/10.1128/MCB.01054-12

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