dr. C.A. (Corry-Anke) Brandsma

Assistant Professor

dr. C.A. (Corry-Anke) Brandsma
E-mail:
c.a.brandsma umcg.nl

Research

  1. 2017
  2. Boorsma, C. E., van der Veen, T. A., Putri, K. S. S., de Almeida, A., Draijer, C., Mauad, T., Fejer, G., Brandsma, C-A., van den Berge, M., Bossé, Y., Sin, D., Hao, K., Reithmeier, A., Andersson, G., Olinga, P., Timens, W., Casini, A., & Melgert, B. N. (2017). A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages. Scientific Reports, 7(1), [12570]. https://doi.org/10.1038/s41598-017-12623-w
  3. Weidner, J., Jarenbäck, L., de Jong, K., Vonk, J. M., van den Berge, M., Brandsma, C-A., Boezen, H. M., Sin, D., Bossé, Y., Nickle, D., Ankerst, J., Bjermer, L., Postma, D. S., Faiz, A., & Tufvesson, E. (2017). Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease. Respiratory Research, 18(1), [77]. https://doi.org/10.1186/s12931-017-0562-5
  4. Li, X., Obeidat, M., Zhou, G., Leung, J. M., Tashkin, D. P., Wise, R., Connett, J., Joubert, P., Bossé, Y., van den Berge, M., Brandsma, C-A., Nickle, D. C., Hao, K., Paré, P. D., & Sin, D. (2017). Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease. EBioMedicine, 19, 139-145. https://doi.org/10.1016/j.ebiom.2017.04.020
  5. Wain, L. V., Shrine, N. R. G., Artigas, M. S., Erzurumluoglu, A. M., Noyvert, B., Bossini-Castillo, L., Obeidat, M., Henrys, A. P., Portelli, M. A., Hall, R. J., Billington, C. K., Rimington, T. L., Fenech, A. G., John, C., Blake, T., Jackson, V. E., Allen, R. J., Prins, B. P., Campbell, A., ... Geisinger-Regeneron DiscovEHR (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 49(3), 416-425. https://doi.org/10.1038/ng.3787
  6. van der Plaat, D. A., de Jong, K., Lahousse, L., Faiz, A., Vonk, J. M., van Diemen, C. C., Nedeljkovic, I., Amin, N., Brusselle, G. G., Hofman, A., Brandsma, C-A., Bossé, Y., Sin, D. D., Nickle, D. C., van Duijn, C. M., Postma, D. S., & Boezen, H. M. (2017). Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A. Journal of Allergy and Clinical Immunology, 139(2), 533-540. https://doi.org/10.1016/j.jaci.2016.06.062
  7. 2016
  8. Morissette, M. C., Gao, Y., Shen, P., Thayaparan, D., Bérubé, J-C., Paré, P. D., Brandsma, C-A., Hao, K., Bossé, Y., Ettinger, R., Herbst, R., Humbles, A. A., Kolbeck, R., Zhong, N., Chen, R., & Stämpfli, M. R. (2016). Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice. Physiological Reports, 4(24), [e13057]. https://doi.org/10.14814/phy2.13057
  9. Dvorkin-Gheva, A., Vanderstocken, G., Yildirim, A. Ö., Brandsma, C-A., Obeidat, M., Bossé, Y., Hassell, J. A., & Stampfli, M. R. (2016). Total particulate matter concentration skews cigarette smoke's gene expression profile. BMJ Open, 2(4). https://doi.org/10.1183/23120541.00029-2016
  10. 2015
  11. Kurakula, K., Vos, M., Logiantara, A., Roelofs, J. J. T. H., Nieuwenhuis, M. A., Koppelman, G. H., Postma, D. S., Brandsma, C. A., Sin, D. D., Bosse, Y., Nickle, D. C., van Rijt, L. S., & de Vries, C. J. M. (2015). Deficiency of FHL2 attenuates airway inflammation in mice and genetic variation associates with human bronchial hyper-responsiveness. Allergy, 70(12), 1531-1544. https://doi.org/10.1111/all.12709
  12. Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., ... UK BiLEVE (2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6, [8658]. https://doi.org/10.1038/ncomms9658
  13. Cheng, Z., Zhou, J., To, K. K-W., Chu, H., Li, C., Wang, D., Yang, D., Zheng, S., Hao, K., Bosse, Y., Obeidat, M., Brandsma, C-A., Song, Y-Q., Chen, Y., Zheng, B-J., Li, L., & Yuen, K-Y. (2015). Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza. Journal of infectious diseases, 212(8), 1214-1221. https://doi.org/10.1093/infdis/jiv246
  14. Dijkstra, A. E., Postma, D. S., van Ginneken, B., Wielpuetz, M. O., Schmidt, M., Becker, N., Owsijewitsch, M., Kauczor, H-U., de Koning, H. J., Lammers, J. W., Oudkerk, M., Brandsma, C-A., Bosse, Y., Nickle, D. C., Sin, D. D., Hiemstra, P. S., Wijmenga, C., Smolonska, J., Zanen, P., ... Groen, H. (2015). Novel Genes for Airway Wall Thickness Identified with Combined Genome-Wide Association and Expression Analyses. American Journal of Respiratory and Critical Care Medicine, 191(5), 547-556. https://doi.org/10.1164/rccm.201405-0840OC
  15. Chen, W., Brehm, J. M., Manichaikul, A., Cho, M. H., Boutaoui, N., Yan, Q., Burkart, K. M., Enright, P. L., Rotter, J. I., Petersen, H., Leng, S., Obeidat, M., Bosse, Y., Brandsma, C-A., Hao, K., Rich, S. S., Powell, R., Avila, L., Soto-Quiros, M., ... Celedon, J. C. (2015). A Genome-Wide Association Study of Chronic Obstructive Pulmonary Disease in Hispanics. Proceedings of the American Thoracic Society, 12(3), 340-348. https://doi.org/10.1513/AnnalsATS.201408-380OC
  16. Chen, Y., Zhou, J., Cheng, Z., Yang, S., Chu, H., Fan, Y., Li, C., Wong, B. H-Y., Zheng, S., Zhu, Y., Yu, F., Wang, Y., Liu, X., Gao, H., Yu, L., Tang, L., Cui, D., Hao, K., Bosse, Y., ... Li, L. (2015). Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9). Scientific Reports, 5, [8517]. https://doi.org/10.1038/srep08517
  17. Brandsma, C-A., van den Berge, M., Postma, D. S., Jonker, M. R., Brouwer, S., Pare, P. D., Sin, D. D., Bosse, Y., Laviolette, M., Karjalainen, J., Fehrmann, R. S. N., Nickle, D. C., Hao, K., Spanjer, A. I. R., Timens, W., & Franke, L. (2015). A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD. Thorax, 70(1), 21-32. https://doi.org/10.1136/thoraxjnl-2014-205091
  18. Dijkstra, A. E., Boezen, H., van den Berge, M., Vonk, J. M., Hiemstra, P. S., Barr, R. G., Burkart, K. M., Manichaikul, A., Pottinger, T. D., Silverman, E. K., Cho, M. H., Crapo, J. D., Beaty, T. H., Bakke, P., Gulsvik, A., Lomas, D. A., Bossé, Y., Nickle, D. C., Paré, P. D., ... the LifeLines Cohort Study group (2015). Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD. European Respiratory Journal, 45(1), 60-75. https://doi.org/10.1183/09031936.00093314
  19. 2014
  20. Lamontagne, M., Timens, W., Hao, K., Bosse, Y., Laviolette, M., Steiling, K., Campbell, J. D., Couture, C., Conti, M., Sherwood, K., Hogg, J. C., Brandsma, C-A., van den Berge, M., Sandford, A., Lam, S., Lenburg, M. E., Spira, A., Pare, P. D., Nickle, D., ... Postma, D. S. (2014). Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. Thorax, 69(11), 997-1004. https://doi.org/10.1136/thoraxjnl-2014-205630
  21. Chen, L., Ge, Q., Tjin, G., Alkhouri, H., Deng, L., Brandsma, C-A., Adcock, I., Timens, W., Postma, D., Burgess, J., Black, J. L., & Oliver, B. G. G. (2014). Effects of cigarette smoke extract on human airway smooth muscle cells in COPD. European Respiratory Journal, 44(3), 634-646. https://doi.org/10.1183/09031936.00171313
  22. Wain, L. V., Sayers, I., Artigas, M. S., Portelli, M. A., Zeggini, E., Obeidat, M., Sin, D. D., Bosse, Y., Nickle, D., Brandsma, C-A., Malarstig, A., Vangjeli, C., Jelinsky, S. A., John, S., Kilty, I., McKeever, T., Shrine, N. R. G., Cook, J. P., Patel, S., ... Tobin, M. D. (2014). Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction. PLoS genetics, 10(5), [e1004314]. https://doi.org/10.1371/journal.pgen.1004314
  23. 2013
  24. Christenson, S. A., Brandsma, C-A., Campbell, J. D., Knight, D. A., Pechkovsky, D. V., Hogg, J. C., Timens, W., Postma, D. S., Lenburg, M., & Spira, A. (2013). miR-638 regulates gene expression networks associated with emphysematous lung destruction. Genome medicine, 5(12), [114]. https://doi.org/10.1186/gm519
  25. 2012
  26. Hao, K., Bosse, Y., Nickle, D. C., Pare, P. D., Postma, D. S., Laviolette, M., Sandford, A., Hackett, T. L., Daley, D., Hogg, J. C., Elliott, W. M., Couture, C., Lamontagne, M., Brandsma, C-A., van den Berge, M., Koppelman, G., Reicin, A. S., Nicholson, D. W., Malkov, V., ... Sin, D. D. (2012). Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma. PLoS genetics, 8(11), [e1003029]. https://doi.org/10.1371/journal.pgen.1003029
  27. Campbell, J. D., McDonough, J. E., Zeskind, J. E., Hackett, T. L., Pechkovsky, D. V., Brandsma, C-A., Suzuki, M., Gosselink, J. V., Liu, G., Alekseyev, Y. O., Xiao, J., Zhang, X., Hayashi, S., Cooper, J. D., Timens, W., Postma, D. S., Knight, D. A., Marc, L. E., James, H. C., & Avrum, S. (2012). A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK. Genome medicine, 4, [67]. https://doi.org/10.1186/gm367

ID: 233733